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Brief Title: Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma
Official Title: The Efficacy of New Adjuvant Chemotherapy of Osteosarcoma Combined With Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma
Study ID: NCT03932071
Brief Summary: Zoledronic acid is an adjuvant treatment for primary osteosarcoma. Zoledronic acid has been widely used in the treatment of metastatic bone tumors. In addition to its inhibition of tumor osteoclasis, it also produces certain killing of tumor cells. effect. Foreign studies have shown that zoledronic acid also has a killing effect on osteosarcoma and has a certain inhibitory effect on distant metastasis. We hope that it can reduce tumor recurrence and lung metastasis through this study.
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
2nd Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, China
Name: zhaoming Ye, Prof.
Affiliation: 2nd Affiliated Hospital Of Zhejiang University
Role: PRINCIPAL_INVESTIGATOR