Spots Global Cancer Trial Database for A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma
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Trial Identification
Brief Title: A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma
Official Title: A Phase 1/2 Study of the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adult Participants With Recurrent or Refractory Classical Hodgkin Lymphoma and Non-Hodgkin Lymphoma
Study ID: NCT05255601
Study Description
Brief Summary: The purpose of this study is to assess the safety, tolerability, drug levels, and preliminary efficacy of relatlimab plus nivolumab in pediatric and young adult participants with recurrent or refractory classical Hodgkin lymphoma and non-Hodgkin lymphoma.
Detailed Description:
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Phoenix Childrens Hospital PCH - Phoenix Childrens Medical Group - Hematology Oncology, Phoenix, Arizona, United States
Lucile Packard Childrens Hospital - Stanford University, Palo Alto, California, United States
Yale University, New Haven, Connecticut, United States
Local Institution - 0061, Wilmington, Delaware, United States
Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida, United States
AdventHealth, Orlando, Florida, United States
St. Mary's Medical Center, West Palm Beach, Florida, United States
The Johns Hopkins Hospital JHH, Baltimore, Maryland, United States
University of Minnesota Medical School - Masonic Childrens Hospital, Minneapolis, Minnesota, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Siteman Cancer Center - Washington University Medical Campus Location, Saint Louis, Missouri, United States
Hackensack University Medical Center HUMC - The Joseph M. Sanzari Childrens Hospital - Children's Cancer Institute, Hackensack, New Jersey, United States
Montefiore Medical Center, Bronx, New York, United States
Columbia University Medical Center, New York, New York, United States
New York Medical College, Valhalla, New York, United States
Penn State Health Milton S. Hershey Medical Center - Penn State Children's Hospital, Hershey, Pennsylvania, United States
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
Dell Children's Medical Center of Central Texas (DCMC) - Strictly Pediatrics Subspecialty Center, Austin, Texas, United States
CHRISTUS Childrens, San Antonio, Texas, United States
UW Health - American Family Children's Hospital Pediatric Bone Marrow Transplant Clinic, Madison, Wisconsin, United States
Local Institution - 0037, Randwick, New South Wales, Australia
Local Institution - 0039, South Brisbane, Queensland, Australia
Local Institution - 0042, Nedlands, Western Australia, Australia
Local Institution - 0063, Angers, Angers Cedex 9, France
Local Institution - 0048, Bordeaux, , France
Local Institution - 0033, Caen, , France
CHU Grenoble Alpes - Hopital Couple Enfant (HCE), La Tronche, , France
Local Institution - 0021, Lyon, , France
Local Institution - 0034, Marseille, , France
Local Institution - 0018, Montpellier, , France
Local Institution - 0006, Paris, , France
Assistance Publique-Hopitaux de Paris AP-HP - Hopital Universitaire Robert-Debre, Paris, , France
Local Institution - 0022, Rennes, , France
CHRU de Strasbourg-Hopital de Hautepierre, Strasbourg, , France
Local Institution - 0056, Aachen, , Germany
Local Institution - 0015, Berlin, , Germany
Local Institution - 0028, Giessen, , Germany
Local Institution - 0036, Hamburg, , Germany
Local Institution - 0008, Muenster, , Germany
Local Institution - 0051, Munich, , Germany
Local Institution - 0041, Pavia, PV, Italy
Local Institution - 0010, Aviano, , Italy
Local Institution - 0007, Bologna, , Italy
Local Institution - 0040, Florence, , Italy
Local Institution - 0005, Genoa, , Italy
Local Institution - 0001, Milano, , Italy
Local Institution - 0070, Milan, , Italy
Local Institution - 0043, Monza, , Italy
Local Institution - 0013, Napoli, , Italy
Local Institution - 0065, Padova, , Italy
Osp. Pediatrico Bambino Gesu, IRCCS, Roma, , Italy
Local Institution - 0004, Turin, , Italy
Princess Maxima Center for pediatric oncology, Utrecht, , Netherlands
Local Institution - 0062, Pamplona, Navarra, Spain
Local Institution - 0046, Barcelona, , Spain
Local Institution - 0009, Barcelona, , Spain
Hospital Sant Juan de Deu Barcelona, Esplugues de Llobregat, , Spain
Local Institution - 0030, Madrid, , Spain
Local Institution - 0058, Madrid, , Spain
Local Institution - 0044, Madrid, , Spain
Local Institution - 0055, Madrid, , Spain
Local Institution - 0045, Madrid, , Spain
Local Institution - 0011, Santander, , Spain
Local Institution - 0038, Sevilla, , Spain
Local Institution - 0023, Sevilla, , Spain
Local Institution - 0049, Valencia, , Spain
Local Institution - 0074, Liverpool, England, United Kingdom
Local Institution - 0054, London, Londonderry, United Kingdom
Local Institution - 0003, Nottingham, Nottinghamshire, United Kingdom
Local Institution - 0050, Bristol, Somerset, United Kingdom
Local Institution - 0053, Sutton, Surrey, United Kingdom
Local Institution - 0031, Birmingham, West Midlands, United Kingdom
Local Institution - 0075, Cambridge, , United Kingdom
Local Institution - 0068, Newcastle upon Tyne, , United Kingdom
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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