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Spots Global Cancer Trial Database for Phase I Study of MLN8237 and Pazopanib in Patients With Solid Tumors

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Phase I Study of MLN8237 and Pazopanib in Patients With Solid Tumors

Official Title: STM-01: Phase I EffTox Study of Aurora A Kinase Inhibitor Alisertib (MLN8237) Given in Combination With Selective VEGFR Inhibitor Pazopanib (Votrient) for Therapy of Solid Tumors

Study ID: NCT01639911

Interventions

Alisertib
Pazopanib

Study Description

Brief Summary: This phase I trial using the EffTox design will evaluate activity and safety of alisertib, an Aurora A kinase inhibitor, when given in combination with the selective VEGFR inhibitor pazopanib in patients with advanced, previously treated non-hematologic solid tumors.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Illinois Cancer Center, Chicago, Illinois, United States

Contact Details

Name: Arkadiusz Z. Dudek, M.D.

Affiliation: University of Illinois at Chicago

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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