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Brief Title: Molecular Genetics Studies of Cancer Patients and Their Relatives
Official Title: Molecular Genetics Studies of Cancer Patients and Their Relatives
Study ID: NCT04185935
Brief Summary: This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.
Detailed Description: PRIMARY OBJECTIVES: I. To identify rare cancer patients and families in whom the pattern of disease suggests a genetic susceptibility to cancer or other etiology suggestive of a carcinogenic exposure and to characterize the underlying predisposition. II. To determine the contribution of heredity (genotype) and biomarkers to clinical outcome (phenotype, occurrence of new cancers, prognosis and quality of life) in subgroups of cancer patients with and without clinical high-risk features. OUTLINE: Patients may provide a sample of blood, a saliva sample, a sample of eyebrow plucks, a sample of urine, and/or stored tumor or healthy tissue.
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Valleywise Comprehensive Health Center - Phoenix, Phoenix, Arizona, United States
John Muir Medical Center-Concord Campus, Concord, California, United States
City of Hope Medical Center, Duarte, California, United States
Saint Jude Medical Center, Fullerton, California, United States
Saddleback Memorial Medical Center, Laguna Hills, California, United States
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
Saint Joseph Hospital - Orange, Orange, California, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California, United States
Cancer Center of Santa Barbara, Santa Barbara, California, United States
Lynn Regional Cancer Center - West, Boca Raton, Florida, United States
Holy Cross Hospital, Fort Lauderdale, Florida, United States
Kootenai Cancer Center, Post Falls, Idaho, United States
John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
Mercy Hospital, Cedar Rapids, Iowa, United States
Suburban Hospital, Bethesda, Maryland, United States
Frederick Oncology Hematology Associates, Frederick, Maryland, United States
Steward Saint Elizabeth's Medical Center, Brighton, Massachusetts, United States
Hunterdon Medical Center, Flemington, New Jersey, United States
Lovelace Medical Center-Downtown, Albuquerque, New Mexico, United States
New Mexico Oncology Hematology Consultants, Albuquerque, New Mexico, United States
Presbyterian Kaseman Hospital, Albuquerque, New Mexico, United States
Mount Kisco Medical Group at Northern Westchester Hospital, Mount Kisco, New York, United States
Health Quest Medical Practice PC-Cardio Thoracic, Poughkeepsie, New York, United States
Aultman Health Foundation, Canton, Ohio, United States
Saint Charles Health System, Bend, Oregon, United States
Paoli Memorial Hospital, Paoli, Pennsylvania, United States
Reading Hospital, West Reading, Pennsylvania, United States
The Don and Sybil Harrington Cancer Center, Amarillo, Texas, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas, United States
Doctor's Hospital of Laredo, Laredo, Texas, United States
Covenant Medical Center, Lubbock, Texas, United States
Saint Agnes Hospital/Agnesian Cancer Center, Fond Du Lac, Wisconsin, United States
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States
Cheyenne Regional Medical Center-West, Cheyenne, Wyoming, United States
Clinica del Country, Bogotá, Cundinamarca, Colombia
Instituto de Cancerologia Las Americas, Medellín, , Colombia
University of Guadalajara, Guadalajara, Jalisco, Mexico
Salvador Zubiran National Institute of Health Sciences and Nutrition, Mexico City, Tlalpan, Mexico
Monterrey Institute of Technology-TecSalud, Nuevo Leon, , Mexico
Instituto Nacional de Enfermedades Neoplasicas, Lima, , Peru
University of Puerto Rico, San Juan, , Puerto Rico
Name: Jeffrey N Weitzel
Affiliation: City of Hope Medical Center
Role: PRINCIPAL_INVESTIGATOR