Spots Global Cancer Trial Database for biospecimen collection

Every month we try and update this database with for biospecimen collection cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)	NCT05564403	Recurrent Bilia... Recurrent Dista... Recurrent Gallb... Recurrent Intra... Stage III Dista... Stage III Hilar... Stage III Intra... Stage IV Distal... Stage IV Hilar ... Stage IV Intrah... Unresectable Bi... Unresectable Di... Unresectable Ga... Unresectable In...	Binimetinib Biopsy Biospecimen Col... Bone Scan Computed Tomogr... Echocardiograph... Fluorouracil Leucovorin Calc... Magnetic Resona... Multigated Acqu... Oxaliplatin	18 Years -	National Cancer Institute (NCI)
Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program	NCT01772771	Glioma Hematopoietic a... Malignant Solid... Melanoma Sarcoma	Biospecimen Col... Genetic Testing Medical Chart R...	-	M.D. Anderson Cancer Center
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma	NCT05235165	Metastatic Mali... Metastatic Oste... Osteosarcoma	Biospecimen Col... Computed Tomogr... Questionnaire A... Thoracoscopy Thoracotomy	- 50 Years	Children's Oncology Group
Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer	NCT03816358	Pancreatic Aden... Stage II Pancre... Stage III Pancr... Stage IV Pancre...	Anetumab Ravtan... Biopsy Biospecimen Col... Gemcitabine Hyd... Ipilimumab Nivolumab	18 Years -	National Cancer Institute (NCI)
Decitabine and Cedazuridine in Combination With Venetoclax for the Treatment of Patients Who Have Relapsed Acute Myeloid Leukemia After Donor Stem Cell Transplant	NCT05799079	Recurrent Acute...	Venetoclax Decitabine Cedazuridine Bone Marrow Asp... Biospecimen Col...	18 Years -	Vanderbilt-Ingram Cancer Center
Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes	NCT04183218	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Localized Esoph... Localized Lung ... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Stage 0 Lung Ca... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung...	Biospecimen Col... Cardiac Event M... Chemoradiothera... Radiation Thera...	18 Years -	Mayo Clinic
Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Mutations or Fusions (MATCH - Subprotocol K2)	NCT06351371	Malignant Solid...	Biopsy Biospecimen Col... Computed Tomogr... Erdafitinib Magnetic Resona...	18 Years -	National Cancer Institute (NCI)
Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery	NCT04955808	Breast Carcinom... Colon Carcinoma Invasive Carcin... Kidney Carcinom... Liver Carcinoma Malignant Solid... Multiple Myelom... Prostate Carcin...	Biospecimen Col... Laboratory Biom...	18 Years -	National Cancer Institute (NCI)
Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer	NCT05911243	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Stage II Pancre... Stage III Pancr... Stage IV Pancre...	Acupressure The... Best Practice Biospecimen Col... Questionnaire A...	18 Years - 65 Years	University of Washington
Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer	NCT01116648	Fallopian Tube ... Ovarian Endomet... Ovarian High Gr... Ovarian Serous ... Ovarian Serous ... Primary Periton... Triple-Negative...	Biopsy Biospecimen Col... Cediranib Malea... Computed Tomogr... Echocardiograph... Magnetic Resona... Multigated Acqu... Olaparib	18 Years -	National Cancer Institute (NCI)
Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies	NCT04068194	Cholangiocarcin... Gallbladder Car... Stage III Gallb... Stage III Hilar... Stage III Intra... Stage IV Gallbl... Stage IV Hilar ... Stage IV Intrah...	Avelumab Biopsy Biospecimen Col... Computed Tomogr... Hypofractionate... Peposertib	18 Years -	National Cancer Institute (NCI)
Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer	NCT03939897	Anatomic Stage ... Metastatic Brea... Metastatic HER2... Metastatic Horm... Recurrent Breas...	Abemaciclib Biopsy Biospecimen Col... Copanlisib Hydr... Diagnostic Imag... Echocardiograph... Fulvestrant Multigated Acqu...	18 Years -	National Cancer Institute (NCI)
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma	NCT04166409	Low Grade Astro... Low Grade Gliom... Metastatic Low ... Metastatic Low ...	Biospecimen Col... Carboplatin Magnetic Resona... Quality-of-Life... Questionnaire A... Selumetinib Sul... Vincristine Sul...	2 Years - 21 Years	National Cancer Institute (NCI)
Pilot Study of Pancreatic Cancer Screening	NCT05058846	Pancreatic Carc...	Biospecimen Col... Magnetic Resona... Magnetic Resona... Endoscopic ultr... Questionnaires	18 Years -	University of California, San Francisco
Genetic Mutational Analysis of Saliva or Buccal Mucosa Samples From Patients With Embryonal or Alveolar Rhabdomyosarcoma	NCT03296371	Alveolar Rhabdo... Embryonal Rhabd...	Biospecimen Col... Laboratory Biom... Questionnaire A...	- 50 Years	Children's Oncology Group
Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)	NCT06210750	T Acute Lymphob... T Lymphoblastic...	Biospecimen Col... Bone Marrow Asp... Bone Marrow Bio... Calaspargase Pe... Computed Tomogr... Cyclophosphamid... Cytarabine Daunorubicin Dexamethasone Doxorubicin Echocardiograph... Lumbar Puncture Mercaptopurine Methotrexate Multigated Acqu... Navitoclax Nelarabine Pegaspargase Positron Emissi... Thioguanine Venetoclax Vincristine X-Ray Imaging	18 Years - 60 Years	National Cancer Institute (NCI)
Pharmacogenomics of Asparaginase Induced Hepatotoxicity	NCT03568266	Acute Lymphobla...	Biospecimen Col...	18 Years -	University of Southern California
Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone Metastasis	NCT03317392	Castration-Resi... Metastatic Pros... Stage IVB Prost...	Biopsy Biospecimen Col... Computed Tomogr... Laboratory Biom... Magnetic Resona... Olaparib Quality-of-Life... Radium Ra 223 D...	18 Years -	National Cancer Institute (NCI)
NCI COVID-19 in Cancer Patients, NCCAPS Study	NCT04387656	COVID-19 Infect... Hematopoietic a... Malignant Solid... Metastatic Mali...	Biospecimen Col... Data Collection Quality-of-Life... Questionnaire A...	-	National Cancer Institute (NCI)
Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation	NCT05806515	Prostate Adenoc... Stage IIIB Pros... Stage IIIC Pros...	Biospecimen Col... Carboplatin Chest Radiograp... Computed Tomogr... Magnetic Resona... PSMA PET Scan Surgical Proced...	18 Years -	SWOG Cancer Research Network
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer	NCT03811015	Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag...	Biospecimen Col... Cisplatin Computed Tomogr... Echocardiograph... Fludeoxyglucose... Intensity-Modul... Nivolumab Patient Observa... Positron Emissi...	18 Years -	National Cancer Institute (NCI)
Somatic Mosaicism in Twins Discordant for Childhood Cancer	NCT06054295	Pediatric Centr... Central Nervous... Discordant Twin Somatic Mutatio...	Biospecimen col... Questionnaire A...	- 18 Years	Children's Oncology Group
CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant	NCT06059391	Acute Lymphobla... Acute Myeloid L... Chronic Lymphoc... Chronic Myeloid... Hematopoietic a... Hodgkin Lymphom... Myelodysplastic... Myelofibrosis Myeloproliferat... Non-Hodgkin Lym...	Allogeneic Hema... Biospecimen Col... Granulocyte Col... Hematopoietic C... Multi-peptide C... Pheresis Placebo Adminis... Stem Cell Mobil...	18 Years -	City of Hope Medical Center
Long Term Followup of Patients Enrolled in MC1137, BEAUTY Study	NCT05703399	Breast Carcinom...	Biospecimen Col... Questionnaire A...	-	Mayo Clinic
Siltuximab for the Prevention of CAR T Cell Related Cytokine Release Syndrome in Patients With CD19 Positive Non-Hodgkin Lymphoma	NCT05665725	Non-Hodgkin Lym...	Biospecimen Col... Computed Tomogr... Positron Emissi... Siltuximab	18 Years -	Ohio State University Comprehensive Cancer Center
Studying Health Outcomes After Treatment in Patients With Retinoblastoma	NCT03932786	Retinoblastoma Cancer Survivor Biological Sibl... Intraocular Ret... Unilateral Reti...	Biospecimen col... Vision assessme... Questionnaire a... Quality of life... Laboratory Biom...	-	Vanderbilt-Ingram Cancer Center
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction	NCT06195306	Breast Atypical... Breast Carcinom... Breast Ductal C... Breast Lobular ...	Biospecimen Col... Mammography Omega-3-Acid Et... Questionnaire A... Random Periareo... Tamoxifen	45 Years - 65 Years	National Cancer Institute (NCI)
Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally Advanced Breast Cancer	NCT05945290	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Early Stage Bre... Locally Advance...	Biospecimen Col... Electronic Heal...	18 Years -	Mayo Clinic
Pembrolizumab and Tazemetostat to Overcome Immune Tolerance Following ASCT or CAR T-cell Therapy in Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma	NCT06242834	B-Cell Non-Hodg...	Biospecimen Col... Computed Tomogr... Echocardiograph... Pembrolizumab Positron Emissi... Tazemetostat	18 Years -	Northwestern University
Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer	NCT00477100	Inflammatory Br... Invasive Breast... Second Primary ...	Biospecimen Col... Interview Medical Chart R... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
High Throughput Drug Sensitivity and Genomics Data in Developing Individualized Treatment in Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia	NCT03389347	Plasma Cell Leu... Recurrent Multi... Refractory Mult...	Biospecimen Col... High Throughput... Laboratory Biom...	18 Years -	University of Washington
NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma	NCT05359211	Recurrent Diffu... Recurrent Diffu... Recurrent Grade... Recurrent Prima... Refractory Diff... Refractory Diff... Refractory Grad... Refractory Prim... Transformed Ind...	Cyclophosphamid... Fludarabine Lisocabtagene M... Polymer-conjuga... X-Ray Imaging Echocardiograph... Multigated Acqu... Bone Marrow Bio... Bone Marrow Asp... Lumbar Puncture Computed Tomogr... Positron Emissi... Biospecimen Col... Biopsy	18 Years -	Fred Hutchinson Cancer Center
Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic Kidney Cancer	NCT06391099	Clinical Stage ... Metastatic Cuta... Metastatic Rena... Stage IV Renal ...	Best Practice Biospecimen Col... Computed Tomogr... Dietary Interve... Educational Act... Glucose Measure... Ketone Measurem... Questionnaire A...	18 Years -	Ohio State University Comprehensive Cancer Center
Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction	NCT06306638	Malignant Solid...	Biospecimen Col... Computed Tomogr... Endobronchial U... Interstitial Ph... Palliative Radi... Physical Perfor... Questionnaire A... Verteporfin	18 Years -	Roswell Park Cancer Institute
Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) With Osimertinib for the Treatment of Patients With Oligoprogressive EGFR Positive Non-small Cell Lung Carcinoma	NCT06014827	Lung Non-Small ... Stage IV Lung C...	Biospecimen Col... Computed Tomogr... Osimertinib Positron Emissi... Stereotactic Bo... Survey Administ...	18 Years -	City of Hope Medical Center
Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer	NCT02446600	Fallopian Tube ... Fallopian Tube ... Fallopian Tube ... Ovarian Clear C... Ovarian Endomet... Ovarian Seromuc... Ovarian Serous ... Ovarian Transit... Ovarian Undiffe... Recurrent Fallo... Recurrent Ovari... Recurrent Ovari... Recurrent Prima...	Biospecimen Col... Carboplatin Cediranib Malea... Computed Tomogr... Echocardiograph... Gemcitabine Gemcitabine Hyd... Laboratory Biom... Magnetic Resona... Multigated Acqu... Olaparib Paclitaxel Pegylated Lipos... Pharmacological... Quality-of-Life...	18 Years -	National Cancer Institute (NCI)
Testing RG1-VLP Vaccine to Prevent HPV-related Cancers	NCT05985681	Human Papilloma...	Biospecimen Col... HPV16 RG1 VLP V... Questionnaire A... Recombinant Hum... Saline	18 Years - 45 Years	National Cancer Institute (NCI)
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer	NCT03816345	Autoimmune Dise... Crohn Disease Dermatomyositis Hematopoietic a... Inflammatory Bo... Malignant Solid... Multiple Sclero... Psoriasis Psoriatic Arthr... Rheumatoid Arth... Sjogren Syndrom... Systemic Lupus ... Systemic Sclero... Ulcerative Coli...	Biospecimen Col... Nivolumab	18 Years -	National Cancer Institute (NCI)
Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations	NCT04548752	Metastatic Panc... Pancreatic Aden... Stage IV Pancre...	Biopsy Biospecimen Col... Computed Tomogr... Magnetic Resona... Olaparib Pembrolizumab	18 Years -	National Cancer Institute (NCI)
Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma	NCT05861050	Blastoid Varian... Mantle Cell Lym... Pleomorphic Var...	Biopsy Biospecimen Col... Bone Marrow Bio... Computed Tomogr... Glofitamab Lenalidomide Obinutuzumab Positron Emissi... Venetoclax	18 Years - 80 Years	City of Hope Medical Center
Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer	NCT04754425	Castration-Resi... Castration-Resi... Metastatic Mali... Metastatic Pros... Metastatic Pros... Stage IV Prosta... Stage IVA Prost... Stage IVB Prost...	Biopsy Biospecimen Col... Erdafitinib	18 Years -	M.D. Anderson Cancer Center
Detection of Plasma DNA Methylation in Peripheral Blood From Patients With Resectable Liver Cancer	NCT04856046	Resectable Hepa...	Biospecimen Col... Electronic Heal...	18 Years -	Mayo Clinic
Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia	NCT05549661	Recurrent Chron... Refractory Chro...	Biospecimen Col... Bone Marrow Asp... Onvansertib Ultrasound Imag...	18 Years -	Mayo Clinic
Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic Kidney Cancer	NCT06391099	Clinical Stage ... Metastatic Cuta... Metastatic Rena... Stage IV Renal ...	Best Practice Biospecimen Col... Computed Tomogr... Dietary Interve... Educational Act... Glucose Measure... Ketone Measurem... Questionnaire A...	18 Years -	Ohio State University Comprehensive Cancer Center
Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors	NCT03878095	Malignant Solid... Refractory Chol... Refractory Mali...	Biopsy Biospecimen Col... Bone Marrow Asp... Bone Marrow Bio... Ceralasertib Computed Tomogr... Magnetic Resona... Olaparib	18 Years -	National Cancer Institute (NCI)
Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma	NCT06160206	Recurrent Gliob... Recurrent WHO G...	Bevacizumab Biospecimen Col... Computed Tomogr... Electronic Heal... Hypofractionate... Magnetic Resona... Retifanlimab	18 Years -	Academic and Community Cancer Research United
Physical Activity in Transfusion Dependent Patients With Myelodysplastic Syndrome	NCT04969367	Myelodysplastic...	Medical Device ... Biospecimen Col... Questionnaire A... Quality-of-Life...	18 Years -	Thomas Jefferson University
A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer	NCT05242965	Lung Non-Small ... Stage IV Lung C...	CD105/Yb-1/SOX2... Sargramostim Computed Tomogr... Biopsy Biospecimen Col...	18 Years -	University of Washington
The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer	NCT05502523	Lung Non-Small ... Stage I Lung Ca... Stage II Lung C... Stage III Lung ...	Pulmonary Arter... Biospecimen Col...	18 Years -	Thomas Jefferson University
Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer	NCT06307548	Locally Advance... Recurrent Color... Stage III Color...	Aminolevulinic ... Biospecimen Col... Computed Tomogr... Fluorescence-Gu... Magnetic Resona... Photodynamic Th... Surgical Proced...	18 Years -	Roswell Park Cancer Institute
A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ	NCT04144023	Breast Ductal C...	Granulocyte-Mac... Multi-epitope H... Therapeutic Con... Echocardiograph... Biospecimen Col... Biopsy	18 Years -	Mayo Clinic
Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer	NCT06287775	Extensive Stage... Stage IV Lung C...	Atezolizumab Biopsy Biospecimen Col... Computed Tomogr... Durvalumab Echocardiograph... Iadademstat Magnetic Resona... Multigated Acqu...	18 Years -	National Cancer Institute (NCI)
Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia	NCT02981628	Recurrent B Acu... Recurrent B Lym... Refractory B Ac... Refractory B Ly...	Asparaginase Er... Biospecimen Col... Bone Marrow Asp... Calaspargase Pe... Cyclophosphamid... Cytarabine Diagnostic Imag... Inotuzumab Ozog... Leucovorin Calc... Lumbar Puncture Methotrexate Pegaspargase Vincristine	1 Year - 21 Years	Children's Oncology Group
Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer	NCT03914300	Differentiated ... Follicular Vari... Poorly Differen... Refractory Diff... Refractory Thyr... Tall Cell Varia... Thyroid Gland F... Thyroid Gland O... Thyroid Gland P...	Biospecimen Col... Cabozantinib S-... Computed Tomogr... Ipilimumab Magnetic Resona... Nivolumab	18 Years -	National Cancer Institute (NCI)
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer	NCT04628767	Renal Pelvis an...	Biopsy Biospecimen Col... Cisplatin Computed Tomogr... Doxorubicin Hyd... Durvalumab Gemcitabine Hyd... Magnetic Resona... Methotrexate Pegfilgrastim Therapeutic Con... Vinblastine Sul...	18 Years -	National Cancer Institute (NCI)
Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma	NCT06232044	Recurrent Multi... Refractory Mult...	Iberdomide Belantamab Mafo... Dexamethasone Echocardiograph... Computed Tomogr... Magnetic Resona... Positron Emissi... Bone Marrow Bio... Bone Marrow Asp... Biospecimen Col...	18 Years -	Alliance for Clinical Trials in Oncology
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma	NCT05045027	Glioma Malignant Gliom... Recurrent Gliom... Recurrent Malig...	Biospecimen Col... Diagnostic Imag... Magnetic Resona...	18 Years -	Jonsson Comprehensive Cancer Center
Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer	NCT06129851	Stage IIC Prost... Stage III Prost... Stage IV Prosta...	Biospecimen Col... Bone Scan Brachytherapy Computed Tomogr... Dual X-ray Abso... External Beam R... Magnetic Resona... PSMA PET Scan Questionnaire A... Relugolix	18 Years -	University of Kansas Medical Center
Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma	NCT05836571	Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Metastatic Undi...	Biopsy Biospecimen Col... Cabozantinib Computed Tomogr... Ipilimumab Magnetic Resona... Nivolumab	18 Years -	National Cancer Institute (NCI)
Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma	NCT05801913	High Grade B-Ce... Intermediate Gr... Recurrent B-Cel... Refractory B-Ce...	Anti-CD19-CAR C... Biospecimen Col... Bone Marrow Bio... Computed Tomogr... Leukapheresis Lymphodepletion... Magnetic Resona... Multi-peptide C... Positron Emissi... X-Ray Imaging	18 Years -	City of Hope Medical Center
Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma	NCT05711615	Metastatic Leio... Metastatic Sarc... Metastatic Soft... Unresectable Le... Unresectable Sa... Unresectable So...	Biopsy Biospecimen Col... Computed Tomogr... Magnetic Resona... Pegylated Lipos... Peposertib	18 Years -	National Cancer Institute (NCI)
Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors	NCT02496208	Bladder Small C... Bladder Squamou... Bladder Urothel... Clear Cell Rena... Invasive Bladde... Invasive Bladde... Invasive Sarcom... Kidney Medullar... Malignant Genit... Malignant Solid... Penile Carcinom... Penile Squamous... Renal Cell Carc... Renal Pelvis Ur... Sarcomatoid Ren... Stage III Bladd... Stage III Penil... Stage III Renal... Stage III Renal... Stage III Renal... Stage III Urete... Stage III Ureth... Stage IV Bladde... Stage IV Penile... Stage IV Renal ... Stage IV Renal ... Stage IV Ureter... Stage IV Urethr... Ureter Urotheli... Urethral Urothe...	Biopsy Biospecimen Col... Cabozantinib S-... Computed Tomogr... Echocardiograph... Ipilimumab Magnetic Resona... Nivolumab	18 Years -	National Cancer Institute (NCI)
Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines	NCT04535401	Advanced Colore... Advanced Digest... Advanced Gastri... Advanced Gastro... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Metastatic Colo... Metastatic Dige... Metastatic Gast... Metastatic Gast... Stage III Color... Stage IV Colore...	Biopsy Biospecimen Col... Diagnostic Imag... Elimusertib Fluorouracil Irinotecan Hydr... Leucovorin Calc...	18 Years -	National Cancer Institute (NCI)
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer	NCT03107780	Glioblastoma Gliosarcoma MGMT-Unmethylat... Recurrent Gliob...	Biospecimen Col... Magnetic Resona... Navtemadlin Radiation Thera...	18 Years -	National Cancer Institute (NCI)
Testing Nivolumab to Prevent Disease From Coming Back After Treatment in Patients With Acute Myeloid Leukemia, REMAIN Trial	NCT02275533	Acute Myeloid L...	Biospecimen Col... Bone Marrow Bio... Clinical Observ... Echocardiograph... Nivolumab	18 Years -	National Cancer Institute (NCI)
Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia	NCT05237960	Erythroplakia Oral Leukoplaki...	Biopsy Biospecimen Col... Extended Releas... Placebo Adminis...	21 Years -	University of Arizona
Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma	NCT03604978	Grade 2 Meningi... Grade 3 Meningi... Recurrent Menin...	Biospecimen Col... Echocardiograph... Ipilimumab Magnetic Resona... Nivolumab Stereotactic Ra...	18 Years -	National Cancer Institute (NCI)
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer	NCT04181060	Advanced Lung N... Metastatic Lung... Recurrent Lung ... Stage IIIB Lung... Stage IV Lung C...	Bevacizumab Biospecimen Col... Computed Tomogr... Echocardiograph... Magnetic Resona... Multigated Acqu... Osimertinib	18 Years -	National Cancer Institute (NCI)
Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment	NCT05432804	MGMT-Methylated... Recurrent Gliob... Recurrent MGMT-...	Biospecimen Col... Magnetic Resona... Selinexor Temozolomide	18 Years -	National Cancer Institute (NCI)
Targeting Inflammation for Endometrial Cancer Prevention	NCT05407025	Endometrial Car...	Biospecimen Col... Questionnaire A...	18 Years -	Mayo Clinic
Metabolite Levels in Ovarian Cancer Patients Receiving Maintenance PARP Inhibitors	NCT04917744	Ovarian Carcino...	Biospecimen Col... Laboratory Biom... Medical Chart R...	-	Mayo Clinic
Cancer Genetic Testing in Ethnic Populations	NCT04475640	Breast Carcinom... Carcinoma of Un... Central Nervous... Digestive Syste... Genitourinary S... Head and Neck C... Malignant Brain... Malignant Femal... Malignant Muscu... Malignant Solid... Skin Carcinoma	Biospecimen Col... Genetic Testing	18 Years -	Mayo Clinic
Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer	NCT06008730	Resectable Lung...	Biospecimen Col... Proton Beam Rad... Radiology, Trea...	18 Years -	Emory University
Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer	NCT06084845	Head and Neck S... Hypopharyngeal ... Laryngeal Squam... Oral Cavity Squ... Oropharyngeal S... Stage III Cutan... Stage III Hypop... Stage III Laryn... Stage III Lip a... Stage III Oroph... Stage IV Cutane... Stage IV Hypoph... Stage IV Laryng... Stage IV Lip an... Stage IV Oropha...	Biospecimen Col... Carboplatin Chest Radiograp... Cisplatin Computed Tomogr... Image Guided Ra... Intensity-Modul... Magnetic Resona... Positron Emissi... Xevinapant	18 Years -	Eastern Cooperative Oncology Group
Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck	NCT05172258	Head and Neck S... Metastatic Head... Metastatic Hypo... Metastatic Lary... Metastatic Oral... Metastatic Orop... Recurrent Head ... Recurrent Hypop... Recurrent Laryn... Recurrent Oral ... Recurrent Oroph... Stage IV Hypoph... Stage IV Laryng... Stage IV Lip an... Stage IV Oropha...	Biopsy Biospecimen Col... Computed Tomogr... Ipatasertib Pembrolizumab	18 Years -	National Cancer Institute (NCI)
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer	NCT01810913	Oropharyngeal p... Stage III Hypop... Stage III Laryn... Stage III Oral ... Stage III Oroph... Stage IV Hypoph... Stage IV Laryng... Stage IV Oral C... Stage IV Oropha...	Atezolizumab Biospecimen Col... Cetuximab Cisplatin Computed Tomogr... Docetaxel Intensity-Modul... Laboratory Biom... Magnetic Resona... Quality-of-Life...	18 Years -	National Cancer Institute (NCI)
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study	NCT03793166	Clear Cell Rena... Metastatic Mali... Metastatic Mali... Metastatic Mali... Metastatic Mali... Sarcomatoid Ren... Stage III Renal... Stage IV Renal ...	Biospecimen Col... Cabozantinib Computed Tomogr... Ipilimumab Magnetic Resona... Nivolumab Quality-of-Life... Questionnaire A...	18 Years -	National Cancer Institute (NCI)
Gluten Free Diet in Diminishing Side Effects Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy	NCT03108911	Acute Myeloid L...	Best Practice Biospecimen Col... Dietary Interve... Laboratory Biom...	18 Years -	Rutgers, The State University of New Jersey
Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer	NCT03233711	Anal Basaloid S... Anal Canal Cloa... Anal Margin Squ... Stage IIB Anal ... Stage III Anal ...	Biopsy Biospecimen Col... Colonoscopy Computed Tomogr... Digital Rectal ... High Resolution... Magnetic Resona... Nivolumab Patient Observa... Proctoscopy Sigmoidoscopy X-Ray Imaging	18 Years -	National Cancer Institute (NCI)
Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer	NCT01902173	Hematopoietic a... Locally Advance... Locally Advance... Metastatic Mali... Metastatic Mela... Stage IIIC Cuta... Stage IV Cutane... Unresectable Ma... Unresectable Me...	Biopsy Biospecimen Col... Computed Tomogr... Dabrafenib Mesy... Magnetic Resona... Trametinib Dime... Uprosertib	18 Years -	National Cancer Institute (NCI)

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