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Brief Title: A Phase 1,Open-label Study of BPI-421286 in Subjects With Advanced Solid Tumors
Official Title: A Phase 1,Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of BPI-421286 in Subjects With Advanced Solid Tumors
Study ID: NCT05315180
Brief Summary: Evaluate the safety and tolerability of BPI-421286 in adult subjects with advanced solid tumors. Estimate the maximum tolerated dose (MTD) and/or a recommended phase 2 dose (RP2D) in adult subjects with advanced solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Shun Lu, Ph.D, Shanghai, Shanghai, China
Dingzhi Huang, Ph.D, Tianjin, Tianjin, China
Wen Li, Ph.D, Hangzhou, Zhejiang, China
Yun Fan,Ph.D, Hangzhou, Zhejiang, China
Shun Lu, Ph.D, Shanghai, , China