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Brief Title: Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment
Official Title: Encorafenib Plus Binimetinib in Patients With Locally Advanced, Unresectable or Metastatic BRAFV600-mutated Melanoma: a Multi-centric, Multinational, Prospective, Longitudinal, Non-interventional Study in Germany, Austria and Switzerland - BERING MELANOMA
Study ID: NCT04045691
Brief Summary: BERING-MELANOMA - designed as a prospective, longitudinal, non-interventional study - investigates real-world effectiveness, quality of life, safety and tolerability of encorafenib plus binimetinib in unresectable advanced or metastatic BRAF(Rapidly Accelerated Fibrosarcoma isoform B)-V600-mutant malignant melanoma after commercial availability of these two products in Germany, Austria and Switzerland. The study focusses on the documentation of the first and second line setting (i.e. after one line of prior checkpoint inhibition) by documenting patients treated according to the SmPC (Summary of Product Characteristics).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
11, Graz, , Austria
13, Innsbruck, , Austria
14, Klagenfurt, , Austria
10, Linz, , Austria
3, Linz, , Austria
12, Salzburg, , Austria
23, Wiener Neustadt, , Austria
22, Wien, , Austria
53, Wien, , Austria
45, Ahaus, , Germany
8, Aschaffenburg, , Germany
56, Augsburg, , Germany
51, Berlin, , Germany
27, Bremerhaven, , Germany
1, Buxtehude, , Germany
43, Chemnitz, , Germany
34, Donauwörth, , Germany
49, Dresden, , Germany
47, Duisburg, , Germany
40, Erfurt, , Germany
20, Essen, , Germany
9, Gera, , Germany
28, Gießen, , Germany
42, Goslar, , Germany
59, Göttingen, , Germany
19, Hamburg, , Germany
21, Hannover, , Germany
2, Heidelberg, , Germany
33, Karlsruhe, , Germany
39, Kiel, , Germany
29, Landshut, , Germany
44, Leipzig, , Germany
30, Ludwigshafen, , Germany
4, Lübeck, , Germany
46, Magdeburg, , Germany
15, Mainz, , Germany
5, Mannheim, , Germany
57, Marburg, , Germany
6, Minden, , Germany
31, München, , Germany
7, München, , Germany
16, Münster, , Germany
35, Münster, , Germany
18, Nürnberg, , Germany
50, Regensburg, , Germany
41, Schorndorf, , Germany
17, Schwerin, , Germany
48, Stolberg, , Germany
55, Trier, , Germany
54, Tübingen, , Germany
32, Zwickau, , Germany
52, Bellinzona, Tessin, Switzerland
38, Aarau, , Switzerland
37, Bern, , Switzerland
24, Chur, , Switzerland
36, Lausanne, , Switzerland
58, Luzern, , Switzerland
26, Winterthur, , Switzerland
25, Zürich, , Switzerland