Spots Global Cancer Trial Database for Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells
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Trial Identification
Brief Title: Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells
Official Title: Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells in Patients With Advanced or Metastatic Tumors.
Study ID: NCT04628806
Interventions
Study Description
Brief Summary: This study investigates the ability of heat shock protein HSP70 to isolate and quantify circulating tumor cells (CTCs) in patients with advanced or metastatic tumors. CTCs will be isolated from peripheral blood before antineoplastic treatment and again after three months. Isolation using HSP70 will be compared with standard CTC isolation by EpCAM. Additionally, imaging parameters of the primary tumor (if available) and metastases will be analysed and correlations between molecular alterations and imaging parameters will be assesed.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Klinik für Radioonkologie und Strahlentherapie, Berlin, , Germany
Contact Details
Name: Sebastian Zschaeck, MD
Affiliation: Charité
Role: PRINCIPAL_INVESTIGATOR
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