Spots Global Cancer Trial Database for Phase II Trial of Allovectin-7® for Metastatic Melanoma
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Trial Identification
Brief Title: Phase II Trial of Allovectin-7® for Metastatic Melanoma
Official Title: A Phase II Study of High-Dose Allovectin-7® in Patients With Advanced Metastatic Melanoma
Study ID: NCT00044356
Interventions
Study Description
Brief Summary: The purpose of this clinical trial is to determine if Allovectin-7®, an experimental gene-based immunotherapy, can shrink melanoma tumors. The trial will also examine if this treatment can improve the time to disease progression.
Detailed Description: Treatment - If you take part in this trial you will be treated for about 10 weeks. You will receive an injection of Allovectin-7® by needle, directly into one or more selected tumors once a week for the first six weeks. The injections may be given in a doctor's office. During a four-week observation period, your disease will be measured to see if the treatment is working. This will be done by general physical exams and scans (such as X-ray scans). Patients who show no sign of disease progression may be offered an option to repeat this treatment course.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Arizona Cancer Center, Tucson, Arizona, United States
University of Arkansas Cancer Research Center, Little Rock, Arkansas, United States
Comprehensive Blood and Cancer Center, Bakersfield, California, United States
University of California, San Francisco, San Francisco, California, United States
University of Colorado Cancer Center, Denver, Colorado, United States
Oncology Specialists, S.C., Park Ridge, Illinois, United States
Louisiana State University Medical Center, New Orleans, Louisiana, United States
Hematology Oncology Associates of Baltimore, Baltimore, Maryland, United States
North Memorial Health Care, Robbinsdale, Minnesota, United States
Mayo Clinic, Rochester, Minnesota, United States
The Melanoma Center of Saint Louis, Saint Louis, Missouri, United States
Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States
Beth Israel Medical Center, New York, New York, United States
Duke University Medical Center, Durham, North Carolina, United States
MD Anderson Cancer Center, Houston, Texas, United States
Cancer Care Alliance, Seattle, Washington, United States
Contact Details
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