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Brief Title: Study of PAT in Patients With Solid Tumor Cancers
Official Title: Phase I Study of Peptide Alarm Therapy (PAT) Administered by Intratumoral Injection With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumor Cancers Who Have Failed 1 or More Prior Therapies
Study ID: NCT05338658
Brief Summary: This is a single center Phase I study with extension of peptide alarm therapy (PAT) administered by intratumoral (IT) injection during the 1st course of a standard of care intravenous PD-1/PD-L1 inhibitor for the treatment of locally advanced or metastatic solid tumor cancers that has failed to be controlled after one or more prior therapies including a previous PD-1/PD-L1 inhibitor
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States
Name: Melissa Geller, MD
Affiliation: Masonic Cancer Center, Univeristy of Minnesota
Role: PRINCIPAL_INVESTIGATOR