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Brief Title: A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change
Official Title: Phase II Study to Examine Precision Radiation in Patients With Pathogenic Mutations in ATM
Study ID: NCT05010031
Brief Summary: This study will test whether reduced-dose radiotherapy is an effective treatment for metastatic tumors with an ATM mutation. The researchers want to find the lowest dose of radiation that would still be effective to treat these tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth (All protocol activities), Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen (All protocol activities), Montvale, New Jersey, United States
Memorial Sloan Kettering Commack (All protocol activities), Commack, New York, United States
Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison, New York, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York, United States
Memorial Sloan Kettering Nassau (All protocol activities), Uniondale, New York, United States
Name: Amy Xu, MD, PhD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR