Spots Global Cancer Trial Database for Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents
Official Title: A Randomized, 2-cohort, Double-blind, Placebo-controlled, Phase III Study of Saruparib (AZD5305) in Combination With Physician's Choice New Hormonal Agents in Patients With HRRm and Non-HRRm Metastatic Castration-Sensitive Prostate Cancer (EvoPAR-Prostate01)
Study ID: NCT06120491
Study Description
Brief Summary: The intention of the study is to demonstrate superiority of Saruparib (AZD5305) + physician's choice NHA relative to placebo + physician's choice NHA by assessment of radiographic progression-free survival (rPFS) in participants with mCSPC.
Detailed Description: Approximately 1800 adult participants with mCSPC will be assigned to one of two cohorts (550 HRRm and 1250 non-HRRm) and randomized in a 1:1 ratio to receive either Saruparib (AZD5305) with NHA or placebo with NHA. They will receive their assigned treatment and regular tumor evaluation scans until disease progression, or until treatment is stopped for another reason. All patients will be followed for survival until the end of the study. Independent data monitoring committee (DMC) composed of independent experts will be convened to confirm the safety and tolerability of Saruparib + physicians choice NHA.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
Research Site, Chandler, Arizona, United States
Research Site, Gilbert, Arizona, United States
Research Site, Phoenix, Arizona, United States
Research Site, Tucson, Arizona, United States
Research Site, Little Rock, Arkansas, United States
Research Site, Springdale, Arkansas, United States
Research Site, Bakersfield, California, United States
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Research Site, Montebello, California, United States
Research Site, Pasadena, California, United States
Research Site, Pomona, California, United States
Research Site, Sacramento, California, United States
Research Site, San Diego, California, United States
Research Site, San Francisco, California, United States
Research Site, Santa Barbara, California, United States
Research Site, Santa Monica, California, United States
Research Site, Santa Rosa, California, United States
Research Site, Golden, Colorado, United States
Research Site, Lakewood, Colorado, United States
Research Site, New Haven, Connecticut, United States
Research Site, Norwich, Connecticut, United States
Research Site, Newark, Delaware, United States
Research Site, Jacksonville, Florida, United States
Research Site, Jacksonville, Florida, United States
Research Site, Palm Bay, Florida, United States
Research Site, Saint Petersburg, Florida, United States
Research Site, Tampa, Florida, United States
Research Site, Atlanta, Georgia, United States
Research Site, Glenview, Illinois, United States
Research Site, Lake Barrington, Illinois, United States
Research Site, Fort Wayne, Indiana, United States
Research Site, Indianapolis, Indiana, United States
Research Site, Des Moines, Iowa, United States
Research Site, Kansas City, Kansas, United States
Research Site, Wichita, Kansas, United States
Research Site, Lexington, Kentucky, United States
Research Site, Louisville, Kentucky, United States
Research Site, Shreveport, Louisiana, United States
Research Site, Scarborough, Maine, United States
Research Site, Annapolis, Maryland, United States
Research Site, Baltimore, Maryland, United States
Research Site, Baltimore, Maryland, United States
Research Site, Bethesda, Maryland, United States
Research Site, Towson, Maryland, United States
Research Site, Grand Rapids, Michigan, United States
Research Site, Troy, Michigan, United States
Research Site, Rochester, Minnesota, United States
Research Site, Columbia, Missouri, United States
Research Site, Billings, Montana, United States
Research Site, Bozeman, Montana, United States
Research Site, Las Vegas, Nevada, United States
Research Site, Las Vegas, Nevada, United States
Research Site, Belleville, New Jersey, United States
Research Site, Brick, New Jersey, United States
Research Site, Camden, New Jersey, United States
Research Site, East Brunswick, New Jersey, United States
Research Site, Voorhees, New Jersey, United States
Research Site, Albuquerque, New Mexico, United States
Research Site, Albuquerque, New Mexico, United States
Research Site, Rio Rancho, New Mexico, United States
Research Site, Albany, New York, United States
Research Site, Bronx, New York, United States
Research Site, New Hyde Park, New York, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Shirley, New York, United States
Research Site, Syracuse, New York, United States
Research Site, Durham, North Carolina, United States
Research Site, Fayetteville, North Carolina, United States
Research Site, Cincinnati, Ohio, United States
Research Site, Cincinnati, Ohio, United States
Research Site, Cleveland, Ohio, United States
Research Site, Cleveland, Ohio, United States
Research Site, Cleveland, Ohio, United States
Research Site, Columbus, Ohio, United States
Research Site, Florence, Oregon, United States
Research Site, Portland, Oregon, United States
Research Site, Portland, Oregon, United States
Research Site, Bala-Cynwyd, Pennsylvania, United States
Research Site, Philadelphia, Pennsylvania, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, York, Pennsylvania, United States
Research Site, Providence, Rhode Island, United States
Research Site, Myrtle Beach, South Carolina, United States
Research Site, North Charleston, South Carolina, United States
Research Site, Sioux Falls, South Dakota, United States
Research Site, Germantown, Tennessee, United States
Research Site, Nashville, Tennessee, United States
Research Site, Dallas, Texas, United States
Research Site, Denton, Texas, United States
Research Site, Flower Mound, Texas, United States
Research Site, Grapevine, Texas, United States
Research Site, Houston, Texas, United States
Research Site, Houston, Texas, United States
Research Site, Houston, Texas, United States
Research Site, Plano, Texas, United States
Research Site, San Antonio, Texas, United States
Research Site, San Antonio, Texas, United States
Research Site, Sugar Land, Texas, United States
Research Site, Tyler, Texas, United States
Research Site, Wichita Falls, Texas, United States
Research Site, Saint George, Utah, United States
Research Site, Salt Lake City, Utah, United States
Research Site, Salt Lake City, Utah, United States
Research Site, Fairfax, Virginia, United States
Research Site, Winchester, Virginia, United States
Research Site, Spokane Valley, Washington, United States
Research Site, Spokane, Washington, United States
Research Site, Tacoma, Washington, United States
Research Site, Chermside, , Australia
Research Site, Darlinghurst, , Australia
Research Site, Hyde Park, , Australia
Research Site, Kurralta Park, , Australia
Research Site, Melbourne, , Australia
Research Site, Randwick, , Australia
Research Site, South Brisbane, , Australia
Research Site, Graz, , Austria
Research Site, Innsbruck, , Austria
Research Site, Krems an der Donau, , Austria
Research Site, Linz, , Austria
Research Site, Wien, , Austria
Research Site, Wien, , Austria
Research Site, Charleroi, , Belgium
Research Site, Gent, , Belgium
Research Site, Kortrijk, , Belgium
Research Site, Leuven, , Belgium
Research Site, Curitiba, , Brazil
Research Site, Pelotas, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Rio de Janeiro, , Brazil
Research Site, Salvador, , Brazil
Research Site, Sao Luis, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, São Paulo, , Brazil
Research Site, Calgary, Alberta, Canada
Research Site, Calgary, Alberta, Canada
Research Site, Edmonton, Alberta, Canada
Research Site, Abbotsford, British Columbia, Canada
Research Site, Kelowna, British Columbia, Canada
Research Site, Vancouver, British Columbia, Canada
Research Site, Winnipeg, Manitoba, Canada
Research Site, Halifax, Nova Scotia, Canada
Research Site, Kingston, Ontario, Canada
Research Site, London, Ontario, Canada
Research Site, Mississauga, Ontario, Canada
Research Site, Newmarket, Ontario, Canada
Research Site, Ottawa, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Chicoutimi, Quebec, Canada
Research Site, Greenfield Park, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Saskatoon, Saskatchewan, Canada
Research Site, Quebec, , Canada
Research Site, Concepcion, , Chile
Research Site, La Serena, , Chile
Research Site, Santiago, , Chile
Research Site, Santiago, , Chile
Research Site, Santiago, , Chile
Research Site, Santiago, , Chile
Research Site, Santiago, , Chile
Research Site, Temuco, , Chile
Research Site, Viña del Mar, , Chile
Research Site, Beijing, , China
Research Site, Beijing, , China
Research Site, Beijing, , China
Research Site, Beijing, , China
Research Site, Beijing, , China
Research Site, Changchun, , China
Research Site, Changsha, , China
Research Site, Chengdu, , China
Research Site, Chongqing, , China
Research Site, Chongqing, , China
Research Site, Dongguan, , China
Research Site, Guangzhou, , China
Research Site, Guangzhou, , China
Research Site, Guilin, , China
Research Site, Hangzhou, , China
Research Site, Hangzhou, , China
Research Site, Harbin, , China
Research Site, Jiaxing, , China
Research Site, Jinan, , China
Research Site, Lanzhou, , China
Research Site, Nanchang, , China
Research Site, Nanchang, , China
Research Site, Nanjing, , China
Research Site, Nantong, , China
Research Site, Ningbo, , China
Research Site, Shandong, , China
Research Site, Shanghai, , China
Research Site, Shanghai, , China
Research Site, Shenyang, , China
Research Site, Shenyang, , China
Research Site, Suining, , China
Research Site, Taiyuan, , China
Research Site, Tianjin, , China
Research Site, WeiFang, , China
Research Site, Wenzhou, , China
Research Site, Wuhan, , China
Research Site, Xi'an, , China
Research Site, Yantai, , China
Research Site, Zhengzhou, , China
Research Site, Helsinki, , Finland
Research Site, Tampere, , Finland
Research Site, Turku, , Finland
Research Site, Angers, , France
Research Site, Aurillac Cedex, , France
Research Site, Bayonne, , France
Research Site, Bordeaux Cedex, , France
Research Site, Caen Cedex 5, , France
Research Site, Clermont Ferrand, , France
Research Site, Lyon, , France
Research Site, Montpellier, , France
Research Site, Nice, , France
Research Site, Nimes, , France
Research Site, Pierre Bénite, , France
Research Site, Poitiers Cedex, , France
Research Site, Quimper Cedex, , France
Research Site, Rennes Cedex 9, , France
Research Site, Strasbourg, , France
Research Site, Tours, , France
Research Site, Vandoeuvre les Nancy, , France
Research Site, Bergisch Gladbach, , Germany
Research Site, Berlin, , Germany
Research Site, Bonn, , Germany
Research Site, Braunschweig, , Germany
Research Site, Dresden, , Germany
Research Site, Duisburg, , Germany
Research Site, Erlangen, , Germany
Research Site, Frankfurt am Main, , Germany
Research Site, Frankfurt, , Germany
Research Site, Freiburg, , Germany
Research Site, Göttingen, , Germany
Research Site, Hamburg, , Germany
Research Site, Heidelberg, , Germany
Research Site, Herne, , Germany
Research Site, Homburg, , Germany
Research Site, Köln, , Germany
Research Site, Magdeburg, , Germany
Research Site, Mannheim, , Germany
Research Site, Marburg, , Germany
Research Site, Mettmann, , Germany
Research Site, München, , Germany
Research Site, Münster, , Germany
Research Site, Nürtingen, , Germany
Research Site, Oldenburg, , Germany
Research Site, Regensburg, , Germany
Research Site, Stuttgart, , Germany
Research Site, Trier, , Germany
Research Site, Tübingen, , Germany
Research Site, Ulm, , Germany
Research Site, Budapest, , Hungary
Research Site, Budapest, , Hungary
Research Site, Budapest, , Hungary
Research Site, Budapest, , Hungary
Research Site, Debrecen, , Hungary
Research Site, Győr, , Hungary
Research Site, Miskolc, , Hungary
Research Site, Nyíregyháza, , Hungary
Research Site, Szekszárd, , Hungary
Research Site, Bangalore, , India
Research Site, Calicut, , India
Research Site, Delhi, , India
Research Site, Hyderabad, , India
Research Site, JAipur, , India
Research Site, Kolkata, , India
Research Site, Kolkata, , India
Research Site, Lucknow, , India
Research Site, Mohali, , India
Research Site, Nagpur, , India
Research Site, New Delhi, , India
Research Site, Pune, , India
Research Site, Surat, , India
Research Site, Vadodara, , India
Research Site, Varanasi, , India
Research Site, Bari, , Italy
Research Site, Genoa, , Italy
Research Site, Meldola, , Italy
Research Site, Milano, , Italy
Research Site, Milano, , Italy
Research Site, Napoli, , Italy
Research Site, Padova, , Italy
Research Site, Rome, , Italy
Research Site, Rozzano, , Italy
Research Site, Terni, , Italy
Research Site, Trento, , Italy
Research Site, Chiba-shi, , Japan
Research Site, Fukuoka-shi, , Japan
Research Site, Fukuoka, , Japan
Research Site, Hirakata-shi, , Japan
Research Site, Hirosaki-shi, , Japan
Research Site, Kanazawa-shi, , Japan
Research Site, Kashihara-shi, , Japan
Research Site, Kawagoe-shi, , Japan
Research Site, Kisarazu-shi, , Japan
Research Site, Kita-gun, , Japan
Research Site, Kobe-shi, , Japan
Research Site, Kumamoto-shi, , Japan
Research Site, Maebashi-shi, , Japan
Research Site, Nagano-shi, , Japan
Research Site, Nagasaki-shi, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Nagoya, , Japan
Research Site, Osaka-shi, , Japan
Research Site, Osakasayama-shi, , Japan
Research Site, Sagamihara-shi, , Japan
Research Site, Sakura-shi, , Japan
Research Site, Sapporo-shi, , Japan
Research Site, Shiwa-gun, , Japan
Research Site, Suita-shi, , Japan
Research Site, Tsu-shi, , Japan
Research Site, Yokohama-shi, , Japan
Research Site, Yufu-shi, , Japan
Research Site, Daejeon, , Korea, Republic of
Research Site, Seongnam-si, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Suwon, , Korea, Republic of
Research Site, George Town, , Malaysia
Research Site, Johor Bahru, , Malaysia
Research Site, Kota Kinabalu, , Malaysia
Research Site, Kuala Lumpur, , Malaysia
Research Site, Kuala Lumpur, , Malaysia
Research Site, Kuching, , Malaysia
Research Site, Amsterdam, , Netherlands
Research Site, Hilversum, , Netherlands
Research Site, Nijmegen, , Netherlands
Research Site, Arequipa, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Bydgoszcz, , Poland
Research Site, Koszalin, , Poland
Research Site, Poznań, , Poland
Research Site, Rzeszów, , Poland
Research Site, Szczecin, , Poland
Research Site, Warszawa, , Poland
Research Site, Wrocław, , Poland
Research Site, Żory, , Poland
Research Site, Barcelona, , Spain
Research Site, Córdoba, , Spain
Research Site, L'Hospitalet de Llobregat, , Spain
Research Site, Lugo, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Sabadell, , Spain
Research Site, Valencia, , Spain
Research Site, Göteborg, , Sweden
Research Site, Malmo, , Sweden
Research Site, Solna, , Sweden
Research Site, Stockholm, , Sweden
Research Site, Kaohsiung city, , Taiwan
Research Site, Kaohsiung, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Taoyuan, , Taiwan
Research Site, Yung Kang City, , Taiwan
Research Site, Bangkok, , Thailand
Research Site, Bangkok, , Thailand
Research Site, Bangkok, , Thailand
Research Site, Chiang Mai, , Thailand
Research Site, Khlong Luang, , Thailand
Research Site, Songkla, , Thailand
Research Site, Ankara, , Turkey
Research Site, Ankara, , Turkey
Research Site, Bornova-Izmir, , Turkey
Research Site, Fatih-Istanbul, , Turkey
Research Site, Istanbul, , Turkey
Research Site, Karsiyaka, , Turkey
Research Site, Aberdeen, , United Kingdom
Research Site, Birmingham, , United Kingdom
Research Site, Cambridge, , United Kingdom
Research Site, Glasgow, , United Kingdom
Research Site, Guildford, , United Kingdom
Research Site, London, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Newcastle upon Tyne, , United Kingdom
Research Site, Oxford, , United Kingdom
Research Site, Plymouth, , United Kingdom
Research Site, Preston, , United Kingdom
Research Site, Swansea, , United Kingdom
Research Site, Truro, , United Kingdom
Contact Details
Name: Kim Nguyen Chi, MD
Affiliation: BC Cancer, Canada
Role: PRINCIPAL_INVESTIGATOR
Name: Arun Azad, MD
Affiliation: Peter MacCallum Cancer Centre, Australia
Role: PRINCIPAL_INVESTIGATOR
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
