⭐️⭐️⭐️⭐️⭐️ "A total no brainer"

⭐️⭐️⭐️⭐️⭐️ "Love this, so easy."

Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer

Official Title: MOUNTAINEER: A Phase II, Open Label Study of Tucatinib Combined With Trastuzumab in Patients With HER2+ Metastatic Colorectal Cancer

Study ID: NCT03043313

Study Description

Brief Summary: This trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself. The participants in this trial have HER2-positive (HER2+) metastatic colorectal cancer (mCRC). 'Metastatic' means that the cancer has spread to other parts of the body. In the first part of this study, participants enrolled into Cohort A and received both tucatinib and trastuzumab. In the second part of this study, participants are randomly assigned to either Cohort B or Cohort C. Participants in Cohort B will receive tucatinib and trastuzumab. Participants in Cohort C will receive tucatinib. Participants in Cohort C who do not respond to therapy may have an option to receive tucatinib plus trastuzumab.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham, Birmingham, Alabama, United States

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States

Mayo Clinic Arizona, Phoenix, Arizona, United States

Pacific Shores Medical Group, Long Beach, California, United States

Keck Medical Center / University of Southern California, Los Angeles, California, United States

Cedars Sinai Medical Center / Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California, United States

Stanford University School of Medicine, Palo Alto, California, United States

Saint Joseph Heritage Medical Group, Santa Rosa, California, United States

Rocky Mountain Cancer Centers - Aurora, Aurora, Colorado, United States

Lombardi Cancer Center / Georgetown University Medical Center, Washington, District of Columbia, United States

Florida Cancer Specialists - South Region, Fort Myers, Florida, United States

Florida Cancer Specialists - North Region, Saint Petersburg, Florida, United States

Winship Cancer Institute / Emory University School of Medicine, Atlanta, Georgia, United States

University of Chicago Medical Center, Chicago, Illinois, United States

Indiana University Simon Cancer Center, Indianapolis, Indiana, United States

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

University of Kansas Cancer Center, Westwood, Kansas, United States

Massachusetts General Hospital, Boston, Massachusetts, United States

Dana Farber Cancer Institute, Boston, Massachusetts, United States

Karmanos Cancer Institute / Wayne State University, Detroit, Michigan, United States

Mayo Clinic Rochester, Rochester, Minnesota, United States

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Duke University Medical Center, Durham, North Carolina, United States

Case Western Reserve University / University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

Northwest Cancer Specialists, P.C., Portland, Oregon, United States

Oregon Health and Science University, Portland, Oregon, United States

Allegheny General Hospital, Pittsburgh, Pennsylvania, United States

Tennessee Oncology-Nashville/Sarah Cannon Research Institute, Nashville, Tennessee, United States

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Texas Oncology - Beaumont, Beaumont, Texas, United States

Texas Oncology - Baylor Sammons Cancer Center, Dallas, Texas, United States

Joe Arrington Cancer Research and Treatment Center, Lubbock, Texas, United States

Texas Oncology - McAllen, McAllen, Texas, United States

Texas Oncology - San Antonio Medical Center, San Antonio, Texas, United States

Texas Oncology - Tyler, Tyler, Texas, United States

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States

Providence Regional Medical Center Everett, Everett, Washington, United States

Seattle Cancer Care Alliance / University of Washington, Seattle, Washington, United States

Aurora Research Institute Cancer Center, Milwaukee, Wisconsin, United States

Cliniques Universitaires Saint Luc, Brussels, Other, Belgium

Universitair Ziekenhuis Antwerpen, Edegem, Other, Belgium

UZ Leuven campus Gasthuisberg, Leuven, Other, Belgium

Hospitalier Jean Minjoz, Besancon, Other, France

Center Georges Francois Leclerc, Dijon, Other, France

Hôpital Franco-Britannique - Fondation Cognacq-Jay, Levallois-Perret, Other, France

Centre Leon Berard - Centre regional de lutte contre le cancer Rhone-Alpes, Lyon, Other, France

Hopital Saint-Antoine, Paris, Other, France

Instituto Europeo di Oncologia, Milan, Other, Italy

Niguarda Ca' Granda Hospital, Milan, Other, Italy

Azienda Ospedaliero-Universitaria Pisana - Ospedale S. Chiara, Pisa, Other, Italy

Hospital Universitario Vall d'Hebron, Barcelona, Other, Spain

Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet), L'Hospitalet de Llobregat, Other, Spain

Hospital General Universitario Gregorio Maranon, Madrid, Other, Spain

Hospital Clinico Universitario de Valencia, Valencia, Other, Spain

Contact Details

Name: John H Strickler

Affiliation: Academic and Community Cancer Research United

Role: STUDY_CHAIR

Name: Jorge Ramos, DO

Affiliation: Seagen Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

Logo

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

spots app storespots app store

Join others from around the world: