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Brief Title: Comparison of Survival Benefit of Panitumumab With Supportive Care to Best Supportive Care Alone in Patients With Metastatic Colorectal Cancer
Official Title: A Phase 3, Multicenter, Randomized, Open-label Trial to Evaluate the Survival Benefit of Panitumumab and Best Supportive Care, Compared to Best Supportive Care Alone, in Subjects With Chemorefractory Wild-type KRAS Metastatic Colorectal Cancer
Study ID: NCT01412957
Brief Summary: The purpose of this study is to evaluate the benefit of panitumumab in addition to best supportive care compared to best supportive care alone in patients with chemorefractory wild-type KRAS (Kirsten rat sarcoma viral oncogene homolog) metastatic colorectal cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Curitiba, Paraná, Brazil
Research Site, Natal, Rio Grande do Norte, Brazil
Research Site, Ijui, Rio Grande do Sul, Brazil
Research Site, Porto Alegre, Rio Grande do Sul, Brazil
Research Site, Greenfield Park, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Québec, Quebec, Canada
Research Site, Trois-Rivières, Quebec, Canada
Research Site, Quebec, , Canada
Research Site, Temuco, Cautín, Chile
Research Site, Vina del Mar, Valparaíso, Chile
Research Site, Fuzhou, Fujian, China
Research Site, Fuzhou, Fujian, China
Research Site, Shijiazhuang, Hebei, China
Research Site, Nanjing, Jiangsu, China
Research Site, Changchun, Jilin, China
Research Site, Shenyang, Liaoning, China
Research Site, Xi An, Shaanxi, China
Research Site, Xi An, Shaanxi, China
Research Site, Beijing, , China
Research Site, Chongqing, , China
Research Site, Chongqing, , China
Research Site, Shanghai, , China
Research Site, Osijek, , Croatia
Research Site, Pula, , Croatia
Research Site, Rijeka, , Croatia
Research Site, Split, , Croatia
Research Site, Zagreb, , Croatia
Research Site, Tallinn, , Estonia
Research Site, Tartu, , Estonia
Research Site, Athens, , Greece
Research Site, Chania, , Greece
Research Site, Hyderabad, Andhra Pradesh, India
Research Site, Visakhapatnam, Andhra Pradesh, India
Research Site, Bangalore, Karnataka, India
Research Site, Kochi, Kerala, India
Research Site, Mumbai, Maharashtra, India
Research Site, Nashik, Maharashtra, India
Research Site, Nashik, Maharashtra, India
Research Site, Pune, Maharashtra, India
Research Site, Chennai, Tamil Nadu, India
Research Site, Goyang-si, Gyeonggi-do, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Daugavpils, , Latvia
Research Site, Riga, , Latvia
Research Site, Riga, , Latvia
Research Site, Kaunas, , Lithuania
Research Site, Vilnius, , Lithuania
Research Site, Nilai, Negri Sembilan, Malaysia
Research Site, Georgetown, Pinang, Malaysia
Research Site, Kuala Lumpur, Wilayah Persekutuan, Malaysia
Research Site, Kuala Lumpur, Wilayah Persekutuan, Malaysia
Research Site, Mexico City, Distrito Federal, Mexico
Research Site, Mexico, Distrito Federal, Mexico
Research Site, Cuernavaca, Morelos, Mexico
Research Site, Oaxaca, , Mexico
Research Site, Davao City, Davao, Philippines
Research Site, Cebu City, , Philippines
Research Site, Manila, , Philippines
Research Site, Manila, , Philippines
Research Site, Pasay City, , Philippines
Research Site, Bucharest, , Romania
Research Site, Bucharest, , Romania
Research Site, Cluj-Napoca, , Romania
Research Site, Cluj-Napoca, , Romania
Research Site, Cluj-Napoca, , Romania
Research Site, Craiova, , Romania
Research Site, Craiova, , Romania
Research Site, Lasi, , Romania
Research Site, Ploiesti, , Romania
Research Site, Suceava, , Romania
Research Site, Timisoara, , Romania
Research Site, Belgrade, , Serbia
Research Site, Nis, , Serbia
Research Site, Sremska Kamenica, , Serbia
Name: MD
Affiliation: Amgen
Role: STUDY_DIRECTOR