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Spots Global Cancer Trial Database for ZN-c3 in Adult Participants With Metastatic Colorectal Cancer

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Trial Identification

Brief Title: ZN-c3 in Adult Participants With Metastatic Colorectal Cancer

Official Title: A Phase 1/2, Open-Label, Multi-Center Study of ZN-c3 Administered in Combination With Encorafenib and Cetuximab in Adults With Metastatic Colorectal Cancer

Study ID: NCT05743036

Study Description

Brief Summary: The purpose of this study is to evaluate the safety, tolerability, and potential clinical benefits of ZN-c3 administered in combination with encorafenib and cetuximab in adult participants with metastatic BRAF V600E mutant colorectal cancer previously treated with one or two treatment regimens.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

USC Norris Comprehensive Cancer Center, Los Angeles, California, United States

Alliance for Multispecialty Research, LLC, Merriam, Kansas, United States

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

The Queen Elizabeth Hospital, Woodville South, South Australia, Australia

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

Hämatologie- Onkologie im Zentrum MVZ GmbH, Augsburg, Bayern, Germany

Klinikum der Universität München Großhadern, Muenchen, Bayern, Germany

Muenchen Klinik Neuperlach, Klinik fuer Haematologie und Onkologie, Muenchen, Bayern, Germany

Institut für Klinisch Onkologische Forschung, Frankfurt, Hessen, Germany

DRK Kliniken Berlin - Köpenick, Berlin, , Germany

Semmelweis University-Department of Internal Medicine and Oncology, Budapest, , Hungary

Clinexpert Kft. Bugat Pal Korhaz, Gyöngyös, , Hungary

Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy

IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy

AOUI Verona, Verona, Veneto, Italy

Istituto Europeo di Oncologia, Milano, , Italy

ASST Grande Ospedale Metropolitano Niguarda, Milano, , Italy

Szpital Uniwersytecki w Krakowie, Kraków, Malopolskie, Poland

Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie, Kraków, Malopolskie, Poland

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie, Warsaw, Mazowieckie, Poland

Opolskie Centrum Onkologii w Opolu im. prof. Tadeusza Koszarowskiego, Opole, Opolskie, Poland

Parc de Salut Mar - Hospital del Mar, Barcelona, Cataluna, Spain

Hospital Universitario Reina Sofia, Córdoba, Cordoba, Spain

Fundación Instituto Valenciano de Oncología, Valencia, Valenciana, Comunitat, Spain

Hospital Universitari Vall d'Hebron, Barcelona, , Spain

Hospital Universitario La Paz, Madrid, , Spain

Hospital Universitario Puerta de Hierro Majadahonda, Madrid, , Spain

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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