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Spots Global Cancer Trial Database for crc

Every month we try and update this database with for crc cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Colorectal Cancer (CRC) Surveillance Tool: Cognitive and Pilot TestingNCT03180411
Colorectal Canc...
Interview
Questionnaire
18 Years - M.D. Anderson Cancer Center
A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid TumorsNCT05668585
Solid Tumors
Melanoma
NSCLC
CRC
ATC
CFT1946
Trametinib
Cetuximab
18 Years - C4 Therapeutics, Inc.
A Study of SGN-BB228 in Advanced Melanoma and Other Solid TumorsNCT05571839
Cutaneous Melan...
Non-small Cell ...
Colorectal Neop...
Pancreatic Neop...
Mesothelioma
SGN-BB228
18 Years - Seagen Inc.
A Phase III Clinical Study of Napabucasin (GB201) Plus FOLFIRI in Adult Patients With Metastatic Colorectal CancerNCT03522649
Previously Trea...
Napabucasin
Fluorouracil
Leucovorin
Irinotecan
18 Years - 1Globe Biomedical Co., Ltd.
Study of HL-085 and Vemurafinib in Metastatic Colorectal Cancer (mCRC)NCT05233332
CRC
HL-085
Vemurafenib
18 Years - 80 YearsShanghai Kechow Pharma, Inc.
A Study of SGN-CEACAM5C in Adults With Advanced Solid TumorsNCT06131840
Colorectal Neop...
Carcinoma, Non-...
Stomach Neoplas...
Pancreatic Duct...
Gastroesophagea...
Small Cell Lung...
SGN-CEACAM5C
18 Years - Seagen Inc.
A Study of [225Ac]-FPI-2059 in Adult Participants With Solid TumoursNCT05605522
Pancreatic Duct...
Squamous Cell C...
Colorectal Canc...
Gastric Cancer
Ewing Sarcoma
NTSR1 Expressin...
Neuroendocrine ...
[225]-FPI-2059
[111In]-FPI-205...
18 Years - Fusion Pharmaceuticals Inc.
Colorectal Cancer Umbrella Protocol - Assessment of Targeted Therapies Against Colorectal Cancer (ATTACC Program) Screening ProtocolNCT01196130
Colorectal Canc...
Cancer Symptom ...
Biomarker Testi...
18 Years - M.D. Anderson Cancer Center
Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationNCT05358249
KRAS G12C Mutan...
Carcinoma, Non-...
Carcinoma, Non-...
Non-Small Cell ...
Non-Small Cell ...
Nonsmall Cell L...
Colorectal Canc...
Colorectal Carc...
Colorectal Neop...
Colorectal Tumo...
Neoplasms, Colo...
JDQ443
trametinib
Ribociclib
cetuximab
18 Years - Novartis
A Study of PRO95780 Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced, Recurrent, and Metastatic Colorectal Cancer (APM4566g)NCT00851136
Metastatic Colo...
bevacizumab
FOLFOX
PRO95780
18 Years - Genentech, Inc.
Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D MutationNCT05737706
Solid Tumor
Advanced Solid ...
Non-small Cell ...
Colo-rectal Can...
Pancreatic Aden...
MRTX1133
18 Years - Mirati Therapeutics Inc.
FIH Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation in ChinaNCT05009329
NSCLC
CRC
Solid Tumor
JAB-21822
JAB-21822
18 Years - Jacobio Pharmaceuticals Co., Ltd.
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid TumorsNCT04557449
Liposarcoma
CRC
Prostate Cancer
Breast Neoplasm...
Adenocarcinoma ...
Solid Tumors
PF-07220060
Letrozole
Fulvestrant
Midazolam
Enzalutamide
18 Years - Pfizer
Screening for Familial Colorectal Cancer (CRC) PatientsNCT00632515
Colorectal Canc...
Questionnaire
- 60 YearsM.D. Anderson Cancer Center
Neoadjuvant Tisleizumab(BGB-A317) for dMMR/MSI-H Non-late Stage CRC Patients Before SurgeryNCT06262581
DMMR Colorectal...
Anti PD-1
Immunotherapy
Tisleizumab(BGB...
18 Years - Sun Yat-sen University
JAB-21822 Activity in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C MutationNCT05002270
Advanced Solid ...
NSCLC
CRC
JAB-21822 (KRAS...
JAB-21822 (KRAS...
JAB-21822 (KRAS...
Cetuximab (EGFR...
18 Years - Jacobio Pharmaceuticals Co., Ltd.
Prevention of Colorectal Cancer Through Multiomics Blood TestingNCT04369053
Colon Cancer
Rectal Cancer
Colon Neoplasm
Colon Diseases
Colon Lesion
Colon Polyp
Colorectal Canc...
Polyp
Adenoma
Rectal Diseases
Gastrointestina...
Freenome test
45 Years - 85 YearsFreenome Holdings Inc.
FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)NCT05432193
Pancreatic Duct...
Colorectal Canc...
Esophageal Canc...
Melanoma (Skin)
Soft Tissue Sar...
Head and Neck S...
Cholangiocarcin...
[Ga-68]-PNT6555
[Lu-177]-PNT655...
18 Years - POINT Biopharma, a wholly owned subsidiary of Eli Lilly and Company
Colon Cancer Screening in First-Degree Relatives of Hispanic Colorectal Cancer (CRC) PatientsNCT00838318
Colorectal Canc...
Interview
18 Years - 70 YearsM.D. Anderson Cancer Center
A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced CancersNCT05544929
Carcinoma, Non-...
Cutaneous Melan...
Carcinoma, Rena...
Carcinoma, Ovar...
Nasopharyngeal ...
Carcinoma, Thym...
Anal Cancer
Mesothelioma
Esophagogastric...
High Microsatel...
Squamous Cell C...
Triple Negative...
KFA115
pembrolizumab
18 Years - Novartis
Neoadjuvant Tisleizumab(BGB-A317) for dMMR/MSI-H Non-late Stage CRC Patients Before SurgeryNCT06262581
DMMR Colorectal...
Anti PD-1
Immunotherapy
Tisleizumab(BGB...
18 Years - Sun Yat-sen University
A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid TumorsNCT05538130
Melanoma
Glioma
Thyroid Cancer
Non-Small Cell ...
Malignant Neopl...
Brain Neoplasms
Colorectal Canc...
PF-07799544
PF-07799933
encorafenib
16 Years - Pfizer
A Study of PDR001 in Combination With LCL161, Everolimus or PanobinostatNCT02890069
Colorectal Canc...
PDR001
LCL161
Everolimus
Panobinostat
QBM076
HDM201
18 Years - Novartis
AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening TestNCT03688906
Colo-rectal Can...
Cancer Colon
Cancer, Rectum
Neoplasms,Color...
Polyps
Polyp of Colon
Adenoma
Adenoma Colon
18 Years - Freenome Holdings Inc.
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid TumorsNCT04913285
Solid Tumor, Ad...
Non-small Cell ...
Melanoma
KIN-2787
KIN-2787 and bi...
18 Years - Pierre Fabre Medicament
A Study of PRO95780 Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced, Recurrent, and Metastatic Colorectal Cancer (APM4566g)NCT00851136
Metastatic Colo...
bevacizumab
FOLFOX
PRO95780
18 Years - Genentech, Inc.
Study of DC-CIK to Treat Colorectal CancerNCT01839539
Colorectal Canc...
dendritic and c...
18 Years - Guangxi Medical University
A Study of PDR001 in Combination With LCL161, Everolimus or PanobinostatNCT02890069
Colorectal Canc...
PDR001
LCL161
Everolimus
Panobinostat
QBM076
HDM201
18 Years - Novartis
PDR001 in Combination With Bevacizumab and mFOLFOX6 as First Line Therapy in Patients With Metastatic MSS Colorectal CancerNCT03176264
Metastatic Colo...
PDR001
bevacizumab
mFOLFOX6
18 Years - Novartis
Engaging Black Men in Colorectal Cancer ScreeningNCT05980182
Colorectal Canc...
CRC
Behavior
mHealth Applica...
45 Years - 74 YearsVirginia Commonwealth University
Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal CarcinomaNCT01394939
Colorectal Carc...
CRC
JX-594
Irinotecan
18 Years - SillaJen, Inc.
Dendritic Cell Vaccination in Patients With Lynch Syndrome or Colorectal Cancer With MSINCT01885702
Colorectal Canc...
DC vaccination
18 Years - 75 YearsRadboud University Medical Center
A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal CancerNCT04322539
Metastatic Colo...
Metastatic Colo...
Fruquintinib
Placebo
18 Years - Hutchmed
Phase Ib Study of PDR001 in Combination With Regorafenib in Adult Patients With Previously Treated Metastatic Colorectal CancerNCT03081494
Metastatic Colo...
spartalizumab (...
regorafenib
18 Years - Novartis
Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal CancerNCT04046445
Colorectal Canc...
MSS
Stage IV Colon ...
Stage IV Rectal...
Metastatic Colo...
Liver Metastasi...
ATP128
BI 754091
VSV-GP128
18 Years - Amal Therapeutics
A Beta-only IL-2 ImmunoTherapY StudyNCT05086692
Advanced Solid ...
Unresectable So...
Clear Cell Rena...
Triple Negative...
Non-Small Cell ...
Non-Small Cell ...
Colorectal Canc...
Gastric Cancer
Cervical Cancer
Basal Cell Carc...
Bladder Cancer
Merkel Cell Car...
Squamous Cell C...
Cutaneous Squam...
Pleural Mesothe...
Esophageal Canc...
Endometrial Car...
Solid Tumor
Solid Tumor, Ad...
MSI-H Solid Mal...
Cancer With A H...
Epithelial Ovar...
Primary Periton...
Gastroesophagea...
Acral Melanoma
Mucosal Melanom...
Cutaneous Melan...
DMMR Solid Mali...
Fallopian Tube ...
Ovarian Cancer
MSI-H Cancer
DMMR Cancer
Pancreas Adenoc...
Skin Cancer
MDNA11
Pembrolizumab
18 Years - Medicenna Therapeutics, Inc.
A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal CancerNCT03597581
Gastrointestina...
Gastrointestina...
Colorectal Canc...
Colorectal Neop...
Colorectal Carc...
Gastric Cancer
Gastric Neoplas...
KRAS Mutation-R...
CRC
Colorectal Canc...
ompenaclid
FOLFIRI
Bevacizumab
FOLFOX regimen
18 Years - Inspirna, Inc.
Addressing Colorectal Cancer in South Florida FirefightersNCT05976282
Colorectal Canc...
CRC
Fecal Immunoche...
Septin9 Test
40 Years - 65 YearsUniversity of Miami
The Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line TreatmentNCT04984369
CRC
HLX208
Cetuximab Injec...
18 Years - Shanghai Henlius Biotech
Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)NCT00628238
Chronic Lymphoc...
CLL
Untreated
Front-line
First-Line
Initial Therapy
Lenalidomide an...
Lenalidomide an...
- Chronic Lymphocytic Leukemia Research Consortium
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal CancerNCT05253651
Colorectal Neop...
tucatinib
trastuzumab
bevacizumab
cetuximab
oxaliplatin
leucovorin
levoleucovorin
fluorouracil
18 Years - Seagen Inc.
A Study in Second Line Metastatic Colorectal CancerNCT01183780
Colorectal Canc...
Ramucirumab
Placebo
Irinotecan
Folinic Acid
5-Fluorouracil
18 Years - Eli Lilly and Company
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RASNCT05379985
Non-small Cell ...
Colorectal Canc...
Pancreatic Duct...
Advanced Solid ...
RMC-6236
18 Years - Revolution Medicines, Inc.
A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced MalignanciesNCT05957367
Colorectal Canc...
GIST
DCC-3116
Ripretinib
Cetuximab
Encorafenib
18 Years - Deciphera Pharmaceuticals LLC
Adagrasib in Combination With BI 1701963 in Patients With Cancer (KRYSTAL 14)NCT04975256
Advanced Cancer
Metastatic Canc...
Malignant Neopl...
Malignant Neopl...
Malignant Neopl...
MRTX849
BI 1701963
18 Years - Mirati Therapeutics Inc.
Neoadjuvant Tisleizumab(BGB-A317) for dMMR/MSI-H Non-late Stage CRC Patients Before SurgeryNCT06262581
DMMR Colorectal...
Anti PD-1
Immunotherapy
Tisleizumab(BGB...
18 Years - Sun Yat-sen University
A Study of Famitinib in Patients With Advanced Colorectal CancerNCT01762293
Colorectal Canc...
Colorectal Canc...
Colorectal Canc...
Famitinib
placebo
18 Years - 70 YearsJiangsu HengRui Medicine Co., Ltd.
A Prospective Study Into the Risk of Colorectal Neoplasms in Individuals With a Family History of Advanced Adenomas (Sibling AN Study)NCT01593098
Adenoma
CRC
40 Years - 70 YearsChinese University of Hong Kong
Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)NCT00628238
Chronic Lymphoc...
CLL
Untreated
Front-line
First-Line
Initial Therapy
Lenalidomide an...
Lenalidomide an...
- Chronic Lymphocytic Leukemia Research Consortium
A Study of PRO95780 in Combination With Cetuximab and Irinotecan Chemotherapy or the FOLFIRI Regimen With Bevacizumab in Patients With Previously Treated Metastatic Colorectal Cancer (APM4187g)NCT00497497
Colorectal Canc...
bevacizumab
cetuximab
FOLFIRI regimen
irinotecan
PRO95780
18 Years - Genentech, Inc.
Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid TumorNCT06105021
Pancreatic Duct...
Non-Small Cell ...
Colorectal Canc...
Solid Tumor
KRAS G12V
AFNT-211
18 Years - Affini-T Therapeutics, Inc.
A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid TumorsNCT03665285
Advanced or Met...
Lung Cancer
Breast Cancer
Head and Neck S...
Endometrial Can...
Melanoma
CRC
Urothelial Carc...
Cholangiocarcin...
NC318
18 Years - NextCure, Inc.
Improving Colorectal Cancer Screening for Diverse Hispanics in Urban Primary CareNCT01569620
Colorectal Canc...
Best clinical p...
Best clinical p...
Best clinical p...
50 Years - 85 YearsIcahn School of Medicine at Mount Sinai
Study of Cabozantinib Plus TAS102 in mCRC as Salvage TherapyNCT04868773
Colorectal Canc...
Colorectal Carc...
Metastatic Canc...
CRC
Cabozantinib
TAS-102
18 Years - 100 YearsUniversity of California, Irvine
Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD ColonoscopyNCT01917513
Adenoma
Polyps
Colorectal Canc...
G-EYE™ colonosc...
Standard Colono...
50 Years - Smart Medical Systems Ltd.
Study to Evaluate D-1553 in Subjects With Solid TumorsNCT04585035
Solid Tumor, Ad...
NSCLC
CRC
D-1553
D-1553 in combi...
18 Years - InventisBio Co., Ltd
A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal CancerNCT00636610
Metastatic Colo...
Vismodegib 150 ...
Placebo to vism...
Bevacizumab
Modified FOLFOX
FOLFIRI
18 Years - Genentech, Inc.
A Phase 1/2 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK PathwayNCT05578092
Solid Tumor
Advanced Solid ...
Non Small Cell ...
Colo-rectal Can...
MRTX0902
MRTX849
18 Years - Mirati Therapeutics Inc.
A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid TumoursNCT02521844
Solid Tumors
ETC-1922159
Pembrolizumab
18 Years - EDDC (Experimental Drug Development Centre), A*STAR Research Entities
Colorectal Cancer (CRC) Surveillance Tool: Cognitive and Pilot TestingNCT03180411
Colorectal Canc...
Interview
Questionnaire
18 Years - M.D. Anderson Cancer Center
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid TumorsNCT03485209
Colorectal Neop...
Carcinoma, Non-...
Exocrine Pancre...
Carcinoma, Squa...
tisotumab vedot...
pembrolizumab
carboplatin
cisplatin
18 Years - Seagen Inc.
SI-B001 as a Single Agent or in Combination With Chemotherapy in the Treatment of Digestive System MalignanciesNCT05039944
Colorectal Canc...
SI-B001
Irinotecan
FOLFIRI Protoco...
FOLFOX Protocol
18 Years - Sichuan Baili Pharmaceutical Co., Ltd.
Phase 1/2 Study to Evaluate Safety, PK and Efficacy of the MYC-Inhibitor OMO-103 in Solid TumoursNCT04808362
Advanced Solid ...
Pancreatic Canc...
CRC
OMO-103
18 Years - Peptomyc S.L.
A Study of Evorpacept (ALX148) With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal CancerNCT05167409
Microsatellite ...
Evorpacept (ALX...
Cetuximab
Pembrolizumab
18 Years - University of Colorado, Denver
Study of NGR-hTNF as Single Agent in Patients Affected by Colorectal Cancer (CRC)NCT00483080
Colorectal Canc...
NGR-hTNF
18 Years - 80 YearsAGC Biologics S.p.A.
Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid TumorsNCT03875313
Solid Tumor
Clear Cell Rena...
TNBC - Triple-N...
Colorectal Canc...
CRC
RCC
ccRCC
CB-839
Talazoparib
18 Years - Calithera Biosciences, Inc
Intratumoral Budding (ITB) in Preoperative Biopsies of Colon and Rectal CancerNCT03336658
CRC
18 Years - Insel Gruppe AG, University Hospital Bern
Study of DC-CIK to Treat Colorectal CancerNCT01839539
Colorectal Canc...
dendritic and c...
18 Years - Guangxi Medical University
Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationNCT05358249
KRAS G12C Mutan...
Carcinoma, Non-...
Carcinoma, Non-...
Non-Small Cell ...
Non-Small Cell ...
Nonsmall Cell L...
Colorectal Canc...
Colorectal Carc...
Colorectal Neop...
Colorectal Tumo...
Neoplasms, Colo...
JDQ443
trametinib
Ribociclib
cetuximab
18 Years - Novartis
Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRCNCT06195670
CRC
Metastatic Colo...
Metastatic Colo...
Experimental
Active Comparat...
18 Years - 85 YearsZhejiang Cancer Hospital
Phase II Study of Minocycline for Reducing Symptom Burden in Colorectal PatientsNCT01906008
Colorectal Canc...
Minocycline
Placebo
Questionnaires
Sensory Test
18 Years - M.D. Anderson Cancer Center
A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid TumorsNCT05538130
Melanoma
Glioma
Thyroid Cancer
Non-Small Cell ...
Malignant Neopl...
Brain Neoplasms
Colorectal Canc...
PF-07799544
PF-07799933
encorafenib
16 Years - Pfizer
Phase 1 and 2 Study of PX-866 and CetuximabNCT01252628
Incurable Metas...
Incurable Progr...
PX-866 (SCCHN)
Cetuximab (SCCH...
PX-866 (CRC)
Cetuximab (CRC)
18 Years - Seagen Inc.
A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)NCT05101382
Colorectal Canc...
Observation
18 Years - IFOM ETS - The AIRC Institute of Molecular Oncology
Donation of Post Mortem Tumor TissuesNCT03385980
NSCLC Stage IV
CRC
CUP
Proteomic analy...
- Niguarda Hospital
Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal CancersNCT04430738
Colorectal Carc...
Gastric Adenoca...
GEJ Adenocarcin...
Esophageal Aden...
Cholangiocarcin...
Gallbladder Car...
tucatinib
trastuzumab
oxaliplatin
leucovorin
fluorouracil
capecitabine
pembrolizumab
18 Years - Seagen Inc.
Azacitidine and CAPOX in Metastatic Colorectal CancerNCT01193517
Colorectal Canc...
Azacitidine
Capecitabine
Oxaliplatin
Azacitidine MTD
18 Years - M.D. Anderson Cancer Center
A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic CancerNCT04844073
Squamous Cell C...
Non-small Cell ...
Colorectal Canc...
TAK-186
18 Years - Takeda
A Study in Second Line Metastatic Colorectal CancerNCT01183780
Colorectal Canc...
Ramucirumab
Placebo
Irinotecan
Folinic Acid
5-Fluorouracil
18 Years - Eli Lilly and Company
Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal NeoplasmsNCT05623787
Peritoneal Carc...
Peritoneal Meta...
Appendix Cancer
Appendix Neopla...
Colorectal Canc...
Whole-body diff...
18 Years - Laval University
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