Spots Global Cancer Trial Database for Proton Beam Re-Irradiation in Thoracic Cancers

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Trial Identification

Brief Title: Proton Beam Re-Irradiation in Thoracic Cancers

Official Title: Definitive Re-irradiation With Proton Beam Radiotherapy for Patients With Recurrent Thoracic Cancers

Study ID: NCT02204761

Conditions

Metastatic Malignant Neoplasm in the Lung

Recurrent Disease

Thoracic Neoplasm

Interventions

Proton Beam Radiation Therapy

Study Description

Brief Summary: This pilot clinical trial studies proton beam radiation therapy in treating patients with thoracic cancer that has come back and have received prior radiation therapy. Proton beam radiation therapy uses high energy protons to kill tumor cells and may cause less damage to normal tissue.

Detailed Description: PRIMARY OBJECTIVES: I. To assess the grade 3 toxicity associated with thoracic re-irradiation with proton therapy, with prospectively applied normal organ radiation dose limits. SECONDARY OBJECTIVES: I. To assess the efficacy of thoracic re-irradiation with proton therapy. OUTLINE: Patients undergo proton beam radiation therapy per standard of care. After completion of study treatment, patients are followed up at 3 months.