Spots Global Cancer Trial Database for proton beam radiation therapy

Every month we try and update this database with for proton beam radiation therapy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer	NCT01629498	Recurrent Lung ... Stage II Non-Sm... Stage IIA Non-S... Stage IIB Non-S... Stage IIIA Non-... Stage IIIB Lung...	Image Guided Ra... Image Guided Ra... Intensity-Modul... Intensity-Modul... Laboratory Biom... Photon Beam Rad... Proton Beam Rad... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
Proton Radiation Therapy in Treating Patients With Prostate Cancer	NCT01045226	Prostate Cancer	Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	Abramson Cancer Center at Penn Medicine
Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer	NCT06008730	Resectable Lung...	Biospecimen Col... Proton Beam Rad... Radiology, Trea...	18 Years -	Emory University
Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer	NCT04725903	Stage III Prost... Stage IIIA Pros... Stage IIIB Pros... Stage IIIC Pros...	High-Dose Rate ... Proton Beam Rad... Quality-of-Life... Survey Administ...	18 Years -	Emory University
PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer	NCT02073968	Metastatic Mali... Recurrent Non-S... Stage IIA Non-S... Stage IIB Non-S... Stage IIIA Non-... Stage IIIB Non-... Stage IV Non-Sm...	Carboplatin Computed Tomogr... Intensity-Modul... Paclitaxel Positron Emissi... Proton Beam Rad...	18 Years -	Albert Einstein College of Medicine
Partial Breast Radiation Therapy in Treating Women Undergoing Breast Conservation Therapy for Early-Stage Breast Cancer	NCT00599989	Breast Cancer Long-term Effec... Skin Reactions ...	adjuvant therap... conventional su... 3-dimensional c... brachytherapy intracavitary b... proton beam rad...	18 Years - 120 Years	Abramson Cancer Center at Penn Medicine
Ultrahypofractionation and Normal Tissue Toxicity	NCT05912231	Breast Cancer Breast Cancer F... Breast Cancer S... Breast Cancer S... Myocardial Fibr...	Accelerated Pro... Accelerated Pho...	18 Years -	Massachusetts General Hospital
Hypofractionated Proton Beam Therapy for Localized Prostate Cancer	NCT01950351	Stage I Prostat... Stage II Prosta...	Laboratory Biom... Proton Beam Rad... Quality-of-Life...	18 Years -	M.D. Anderson Cancer Center
Proton Radiation Therapy in Treating Patients With Prostate Cancer	NCT01045226	Prostate Cancer	Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	Abramson Cancer Center at Penn Medicine
Proton Beam Radiation Therapy for Intraocular and Periocular Retinoblastoma	NCT00432445	Retinoblastoma	Proton Beam Rad... Ophthalmic EUA	-	M.D. Anderson Cancer Center
Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer	NCT04870840	Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Malignant Poste... Stage II Cutane... Stage II Hypoph... Stage II Laryng... Stage II Nasoph... Stage II Oropha... Stage III Cutan... Stage III Hypop... Stage III Laryn... Stage III Nasop... Stage III Oroph... Unresectable He... Unresectable Or...	Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer	NCT01629498	Recurrent Lung ... Stage II Non-Sm... Stage IIA Non-S... Stage IIB Non-S... Stage IIIA Non-... Stage IIIB Lung...	Image Guided Ra... Image Guided Ra... Intensity-Modul... Intensity-Modul... Laboratory Biom... Photon Beam Rad... Proton Beam Rad... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy	NCT03778294	Glioblastoma Malignant Gliom...	Computed Tomogr... Fluorodopa F 18 Magnetic Resona... Positron Emissi... Proton Beam Rad... Quality-of-Life... Questionnaire A... Temozolomide	65 Years -	Mayo Clinic
Proton Beam Re-Irradiation in Thoracic Cancers	NCT02204761	Metastatic Mali... Recurrent Disea... Thoracic Neopla...	Proton Beam Rad...	19 Years -	University of Washington
Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas	NCT01024907	Adult Brain Tum... Adult Brain Ste... Adult Diffuse A... Adult Ependymom... Adult Grade II ... Adult Melanocyt... Adult Meningeal... Adult Mixed Gli... Adult Oligodend... Adult Pineal Gl... Adult Pineocyto... Recurrent Adult...	proton beam rad... quality-of-life... questionnaire a...	18 Years -	Abramson Cancer Center at Penn Medicine
Partial Breast Radiation Therapy in Treating Women Undergoing Breast Conservation Therapy for Early-Stage Breast Cancer	NCT00599989	Breast Cancer Long-term Effec... Skin Reactions ...	adjuvant therap... conventional su... 3-dimensional c... brachytherapy intracavitary b... proton beam rad...	18 Years - 120 Years	Abramson Cancer Center at Penn Medicine
Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery	NCT03132532	Recurrent Lung ... Stage II Lung C... Stage III Lung ... Unresectable Lu...	Carboplatin Cisplatin Etoposide Paclitaxel Pemetrexed Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	Mayo Clinic
Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer	NCT04870840	Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Malignant Poste... Stage II Cutane... Stage II Hypoph... Stage II Laryng... Stage II Nasoph... Stage II Oropha... Stage III Cutan... Stage III Hypop... Stage III Laryn... Stage III Nasop... Stage III Oroph... Unresectable He... Unresectable Or...	Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer	NCT04870840	Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Malignant Poste... Stage II Cutane... Stage II Hypoph... Stage II Laryng... Stage II Nasoph... Stage II Oropha... Stage III Cutan... Stage III Hypop... Stage III Laryn... Stage III Nasop... Stage III Oroph... Unresectable He... Unresectable Or...	Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)	NCT06239272	Non-rhabdomyosa... Adipocytic Neop... Liposarcoma	Surgical resect... Proton beam rad... Pazopanib Ifosfamide Doxorubicin Selinexor	- 30 Years	St. Jude Children's Research Hospital
Proton Radiation Therapy in Treating Patients With Prostate Cancer	NCT01045226	Prostate Cancer	Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	Abramson Cancer Center at Penn Medicine
Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients	NCT04443413	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ...	Proton Beam Rad... Questionnaire A... X-ray Therapy	18 Years -	Mayo Clinic
O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas	NCT00669669	Glioblastoma Gliosarcoma	3-Dimensional C... Autologous Hema... Carmustine Filgrastim In Vitro-Treate... Intensity-Modul... Laboratory Biom... O6-Benzylguanin... Plerixafor Proton Beam Rad... Temozolomide	18 Years -	Fred Hutchinson Cancer Center
Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer	NCT04725903	Stage III Prost... Stage IIIA Pros... Stage IIIB Pros... Stage IIIC Pros...	High-Dose Rate ... Proton Beam Rad... Quality-of-Life... Survey Administ...	18 Years -	Emory University
Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients	NCT04443413	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ...	Proton Beam Rad... Questionnaire A... X-ray Therapy	18 Years -	Mayo Clinic
Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer	NCT01893307	Stage III Oroph... Stage IVA Oroph... Stage IVB Oroph...	Intensity-Modul... Intensity-Modul... Laboratory Biom... Photon Beam Rad... Proton Beam Rad... Quality-of-Life...	18 Years -	M.D. Anderson Cancer Center
O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas	NCT00669669	Glioblastoma Gliosarcoma	3-Dimensional C... Autologous Hema... Carmustine Filgrastim In Vitro-Treate... Intensity-Modul... Laboratory Biom... O6-Benzylguanin... Plerixafor Proton Beam Rad... Temozolomide	18 Years -	Fred Hutchinson Cancer Center
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma	NCT04671667	Recurrent Head ... Recurrent Hypop... Recurrent Laryn... Recurrent Oral ... Recurrent Oroph...	Carboplatin Cisplatin Computed Tomogr... Intensity-Modul... Magnetic Resona... Pembrolizumab Proton Beam Rad...	18 Years - 79 Years	National Cancer Institute (NCI)
Proton Beam Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Can Be Removed By Surgery	NCT01076231	Stage IIIA Non-...	proton beam rad... cisplatin etoposide therapeutic con...	18 Years -	Abramson Cancer Center at Penn Medicine
Hypofractionated Proton Beam Therapy for Localized Prostate Cancer	NCT01950351	Stage I Prostat... Stage II Prosta...	Laboratory Biom... Proton Beam Rad... Quality-of-Life...	18 Years -	M.D. Anderson Cancer Center
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)	NCT06239272	Non-rhabdomyosa... Adipocytic Neop... Liposarcoma	Surgical resect... Proton beam rad... Pazopanib Ifosfamide Doxorubicin Selinexor	- 30 Years	St. Jude Children's Research Hospital
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma	NCT04671667	Recurrent Head ... Recurrent Hypop... Recurrent Laryn... Recurrent Oral ... Recurrent Oroph...	Carboplatin Cisplatin Computed Tomogr... Intensity-Modul... Magnetic Resona... Pembrolizumab Proton Beam Rad...	18 Years - 79 Years	National Cancer Institute (NCI)
Radiation Therapy (Hypofractionated Proton Beam Therapy or IMRT) for the Treatment of Recurrent, Oligometastatic Prostate Cancer Following Primary Localized Treatment	NCT04190446	Metastatic Pros... Oligometastatic... Prostate Adenoc... Recurrent Prost... Stage IV Prosta...	Intensity-Modul... Proton Beam Rad... Quality-of-Life... Questionnaire A... Computed Tomogr... Magnetic Resona... Biospecimen Col...	18 Years -	Mayo Clinic
Radiation Therapy (Hypofractionated Proton Beam Therapy or IMRT) for the Treatment of Recurrent, Oligometastatic Prostate Cancer Following Primary Localized Treatment	NCT04190446	Metastatic Pros... Oligometastatic... Prostate Adenoc... Recurrent Prost... Stage IV Prosta...	Intensity-Modul... Proton Beam Rad... Quality-of-Life... Questionnaire A... Computed Tomogr... Magnetic Resona... Biospecimen Col...	18 Years -	Mayo Clinic
Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer	NCT03801876	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Thoracic Esopha...	Carboplatin Esophagectomy Intensity-Modul... Paclitaxel Proton Beam Rad... Quality-of-Life... Questionnaire A... FOLFOX regimen CAPOX regimen Docetaxel 5FU	18 Years -	NRG Oncology
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)	NCT06239272	Non-rhabdomyosa... Adipocytic Neop... Liposarcoma	Surgical resect... Proton beam rad... Pazopanib Ifosfamide Doxorubicin Selinexor	- 30 Years	St. Jude Children's Research Hospital
Radiation Therapy (Hypofractionated Proton Beam Therapy or IMRT) for the Treatment of Recurrent, Oligometastatic Prostate Cancer Following Primary Localized Treatment	NCT04190446	Metastatic Pros... Oligometastatic... Prostate Adenoc... Recurrent Prost... Stage IV Prosta...	Intensity-Modul... Proton Beam Rad... Quality-of-Life... Questionnaire A... Computed Tomogr... Magnetic Resona... Biospecimen Col...	18 Years -	Mayo Clinic
Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer	NCT01993810	Stage II Non-Sm... Stage IIA Non-S... Stage IIB Non-S... Stage III Non-S... Stage IIIA Non-... Stage IIIB Non-...	Carboplatin Cisplatin Durvalumab Etoposide Paclitaxel Pemetrexed Diso... Photon Beam Rad... Proton Beam Rad... Quality-of-Life... Questionnaire A...	18 Years -	Radiation Therapy Oncology Group
Proton Beam Radiation Therapy in Treating Patients With Retroperitoneal Sarcoma	NCT01034566	Adult Soft Tiss...	Proton Beam Rad...	18 Years -	Abramson Cancer Center at Penn Medicine
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma	NCT04671667	Recurrent Head ... Recurrent Hypop... Recurrent Laryn... Recurrent Oral ... Recurrent Oroph...	Carboplatin Cisplatin Computed Tomogr... Intensity-Modul... Magnetic Resona... Pembrolizumab Proton Beam Rad...	18 Years - 79 Years	National Cancer Institute (NCI)
Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer	NCT01245712	Breast Adenocar... Ductal Breast C... Invasive Breast... Stage 0 Breast ... Stage I Breast ... Stage IA Breast... Stage IB Breast... Stage II Breast... Stage IIA Breas... Stage IIB Breas...	Accelerated Par... Proton Beam Rad... Quality-of-Life...	18 Years -	M.D. Anderson Cancer Center

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

Join others from around the world: