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Spots Global Cancer Trial Database for Circulating Tumor Cells and Melanoma: Comparing the EPISPOT and CellSearch Techniques

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Trial Identification

Brief Title: Circulating Tumor Cells and Melanoma: Comparing the EPISPOT and CellSearch Techniques

Official Title: Circulating Tumor Cells and Melanoma: Comparing the EPISPOT (EPithelial ImmunoSPOT) and CellSearch Techniques

Study ID: NCT01558349

Interventions

Study Description

Brief Summary: The main objective of this study is to compare results for the detection of circulating melanoma cells (CMC) using CellSearch versus EPISPOT (EPithelial ImmunoSPOT) techniques between a group of patients with metastatic melanoma and a group of hospitalized control patients.

Detailed Description: The secondary objectives of this study include: A. To compare the following elements between the two patient groups: * the number of CMCs per ml of blood as determined by EPISPOT * the number of CMCs per ml of blood as determined by CellSearch * the percentage of patients with at least 2 CMCs per ml of blood according to the two techniques * the % of CMCs expressing KI67 * the % of CMCs expressions S100 (only the EPISPOT technique) B. To compare the EPISPOT and CellSearch techniques is terms of the following: * the number of CMCs detected per ml blood * the number of CMCs expressing antigen KI67 C. To re-evaluate the 2-CMC per ml blood threshold

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

CHU de Montpellier - Hôpital Saint-Eloi, Montpellier, , France

CHU de Nîmes - Hôpital Universitaire Carémeau, Nîmes Cedex 09, , France

Contact Details

Name: Laurent Meunier, MD

Affiliation: Centre Hospitalier Universitaire de Nîmes

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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