Spots Global Cancer Trial Database for Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM.
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Trial Identification
Brief Title: Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM.
Official Title: Large Scale Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From Monoclonal Gammopathy of Undetermined Significance (MGUS) and Indolent Myeloma (SMM).
Study ID: NCT01079429
Interventions
Study Description
Brief Summary: The purpose of this study is to describe DNA copy number variations and gene expression profiles of bone marrow plasma cells of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). The final objective is to search for correlations with the risk of progression in order to establish a predictive model of early malignant transformation.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Rennes University Hospital, Rennes, Bretagne, France
Nantes University Hospital, Nantes, Pays De Loire, France
CHU Amiens - médecine interne, Amiens, , France
CHU Angers, Angers, , France
Centre Hospitalier H.Duffaut - Avignon, Avignon, , France
Hôpital Jean Minjoz - Besancon, Besancon, , France
Service de Médecine interne - Centre Hospitalier, Blois, , France
Bordeaux Bergonié, Bordeaux, , France
Bordeaux Haut Leveque, Bordeaux, , France
Polyclinique Bordeaux Nord Aquitaine, Bordeaux, , France
Hôpital A.Morvan Brest, Brest, , France
Centre F.Baclesse, Caen, , France
CHU Caen, Caen, , France
Hôpital d'instruction des armées Percy, Clamart, , France
CHU Clermont Ferrand, Clermont Ferrand, , France
CH Colmar, Colmar, , France
CH Dijon, Dijon, , France
CHG Dunkerque, Dunkerque, , France
CH Grenoble, Grenoble, , France
CH La Roche sur yon, La Roche sur yon, , France
CH Laval, Laval, , France
Le Mans Victor Hugo, Le Mans, , France
Hôpital Claude Huriez, Lille, , France
Centre Hospitalier Yves Le Foll de Saint Brieuc - Service d'Hématologie, Saint Brieuc, , France
CHU Toulouse Purpan, Toulouse, , France
CHU Toulouse Rangueil, Toulouse, , France
Service d'Hématologie - Hôpital de Brabois, Vandoeuvre, , France
Contact Details
Name: Olivier DECAUX, MD
Affiliation: Rennes University Hospital
Role: PRINCIPAL_INVESTIGATOR
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