Spots Global Cancer Trial Database for monoclonal gammopathy of undetermined significance
Every month we try and update this database with for monoclonal gammopathy of undetermined significance cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The CHAPERONE Study | NCT05965115 | Multiple Myelom... Monoclonal Gamm... | Sample of Blood | 18 Years - | Shanghai Zhongshan Hospital | |
| Screening to Improve Survival in AL Amyloidosis | NCT04615572 | Smoldering Mult... Monoclonal Gamm... | 60 Years - | Tufts Medical Center | ||
| Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma | NCT04850846 | Monoclonal Gamm... Smoldering Mult... | Metformin XR Placebo | 18 Years - | Dana-Farber Cancer Institute | |
| A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) | NCT05640843 | Multiple Myelom... Monoclonal Gamm... | Whole Foods Pla... Algae omega 3 Placebo supplem... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| MGUS, SMM, and MM Patient Experience With Coronavirus 19 (COVID-19) Survey | NCT04727294 | Multiple Myelom... Smoldering Mult... Monoclonal Gamm... Coronavirus | Questionnaire | 18 Years - | HealthTree Foundation | |
| Screening to Improve Survival in AL Amyloidosis | NCT04615572 | Smoldering Mult... Monoclonal Gamm... | 60 Years - | Tufts Medical Center | ||
| Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma | NCT00942422 | Multiple Myelom... Precancerous Co... | defined green t... gene expression... protein analysi... laboratory biom... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Systemic Mastocytosis | NCT00132015 | Chronic Myelopr... Leukemia Lymphoma Nonneoplastic C... Precancerous Co... | tanespimycin | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Beta Alethine in Treating Patients With Myeloma | NCT00006466 | Multiple Myelom... Precancerous Co... | beta alethine | 18 Years - | National Cancer Institute (NCI) | |
| The Indiana Myeloma Registry | NCT03616483 | Plasma Cell Dys... | This is a non-i... | 18 Years - | Indiana University | |
| Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization | NCT04439006 | Aplastic Anemia Hematopoietic a... Malignant Solid... Monoclonal B-Ce... Monoclonal Gamm... Myelodysplastic... Symptomatic COV... | Best Practice Ibrutinib | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Sleep Apnea in Patients With MGUS and MM | NCT04114084 | Multiple Myelom... Monoclonal Gamm... | Bone Marrow Asp... | 18 Years - 99 Years | University of Iowa | |
| A Study Evaluating the Effects of Siltuximab on the Heart in Patients With Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma, or Indolent Multiple Myeloma | NCT01219010 | Monoclonal Gamm... Multiple Myelom... Plasma Cell Neo... | Siltuximab | 18 Years - | Janssen Research & Development, LLC | |
| Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma | NCT04850846 | Monoclonal Gamm... Smoldering Mult... | Metformin XR Placebo | 18 Years - | Dana-Farber Cancer Institute | |
| Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies | NCT05136807 | Monoclonal Gamm... Smoldering Plas... | Quality-of-Life... Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center | |
| S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS. | NCT00919139 | Multiple Myelom... Smoldering Myel... Waldenstrom's M... Monoclonal Gamm... Amyloidosis | biologic sample... | - | SWOG Cancer Research Network | |
| Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma | NCT04850846 | Monoclonal Gamm... Smoldering Mult... | Metformin XR Placebo | 18 Years - | Dana-Farber Cancer Institute | |
| PS-341 in Treating Patients With Advanced Cancer | NCT00006362 | Leukemia Lymphoma Multiple Myelom... Precancerous Co... Unspecified Adu... | bortezomib | 18 Years - | Mayo Clinic | |
| Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma | NCT00942422 | Multiple Myelom... Precancerous Co... | defined green t... gene expression... protein analysi... laboratory biom... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Prevention of Disease Progression in Early Stage Indolent B Cell Malignancies. (SMM) | NCT00899353 | Monoclonal Gamm... Smoldering Mult... Chronic Lymphoc... | Omega 3 Fatty A... | 18 Years - | Marshall University | |
| Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer | NCT04731844 | Prostate Cancer Multiple Myelom... Smoldering Mult... Monoclonal Gamm... | Curcumin plus P... | 18 Years - | University of Rochester | |
| Genomic and Psychosocial Effects of the 3RP on Patients With MGUS and Smoldering Multiple Myeloma | NCT01955395 | Monoclonal Gamm... Smoldering Mult... | Relaxation Resp... | 18 Years - | Massachusetts General Hospital | |
| Rituximab in Treating Patients With Peripheral Neuropathy Caused by Monoclonal Gammopathy of Undetermined Significance | NCT00588822 | Precancerous Co... | Rituximab | 21 Years - 90 Years | Mayo Clinic | |
| Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma | NCT03119883 | Monoclonal Gamm... Plasma Cell Mye... | 5-Carbon C 13-l... Biospecimen Col... Biospecimen Col... Uniformly-label... | 18 Years - | Mayo Clinic | |
| A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) | NCT05640843 | Multiple Myelom... Monoclonal Gamm... | Whole Foods Pla... Algae omega 3 Placebo supplem... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM. | NCT01079429 | Monoclonal Gamm... Smoldering Myel... | Genetic study o... | 18 Years - 70 Years | Rennes University Hospital | |
| Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma | NCT02726750 | Monoclonal Gamm... Smoldering Plas... | Biospecimen Col... Laboratory Biom... | 18 Years - | M.D. Anderson Cancer Center | |
| B-Cell Hematologic Malignancy Vaccination Registry | NCT02298816 | Monoclonal Gamm... Multiple Myelom... Waldenstrom Mac... Lymphocytosis Lymphoma, Non-H... B-Cell Chronic ... Hematological M... | - | Aurora Health Care | ||
| Promoting Diagnosis and Management of AL in Italy (ProDigALIty) | NCT06383143 | AL Amyloidosis Smoldering Mult... Monoclonal Gamm... | no intervention | 18 Years - 99 Years | IRCCS Policlinico S. Matteo | |
| A Study of a Plant-Based Diet in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) | NCT04920084 | Monoclonal Gamm... Smoldering Mult... | Plant based mea... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization | NCT04439006 | Aplastic Anemia Hematopoietic a... Malignant Solid... Monoclonal B-Ce... Monoclonal Gamm... Myelodysplastic... Symptomatic COV... | Best Practice Ibrutinib | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Screening to Improve Survival in AL Amyloidosis | NCT04615572 | Smoldering Mult... Monoclonal Gamm... | 60 Years - | Tufts Medical Center | ||
| The Indiana Myeloma Registry | NCT03616483 | Plasma Cell Dys... | This is a non-i... | 18 Years - | Indiana University | |
| B-Cell Hematologic Malignancy Vaccination Registry | NCT02298816 | Monoclonal Gamm... Multiple Myelom... Waldenstrom Mac... Lymphocytosis Lymphoma, Non-H... B-Cell Chronic ... Hematological M... | - | Aurora Health Care | ||
| Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM. | NCT01079429 | Monoclonal Gamm... Smoldering Myel... | Genetic study o... | 18 Years - 70 Years | Rennes University Hospital | |
| Promoting Diagnosis and Management of AL in Italy (ProDigALIty) | NCT06383143 | AL Amyloidosis Smoldering Mult... Monoclonal Gamm... | no intervention | 18 Years - 99 Years | IRCCS Policlinico S. Matteo | |
| Beta Alethine in Treating Patients With Myeloma | NCT00006466 | Multiple Myelom... Precancerous Co... | beta alethine | 18 Years - | National Cancer Institute (NCI) | |
| Isatuximab in Type I Cryoglobulinemia | NCT05114109 | Multiple Myelom... Monoclonal Gamm... Cryoglobulinemi... | Isatuximab Inje... | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma | NCT00942422 | Multiple Myelom... Precancerous Co... | defined green t... gene expression... protein analysi... laboratory biom... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM. | NCT01079429 | Monoclonal Gamm... Smoldering Myel... | Genetic study o... | 18 Years - 70 Years | Rennes University Hospital | |
| Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource | NCT01408225 | Plasma Cell Dys... Monoclonal Gamm... AL Amyloidosis Multiple Myelom... | tissue banking | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Celecoxib in Preventing Multiple Myeloma in Patients With Monoclonal Gammopathy or Smoldering Myeloma | NCT00099047 | Monoclonal Gamm... Multiple Myelom... Smoldering Mult... | celecoxib placebo laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer | NCT04731844 | Prostate Cancer Multiple Myelom... Smoldering Mult... Monoclonal Gamm... | Curcumin plus P... | 18 Years - | University of Rochester | |
| Genomic and Psychosocial Effects of the 3RP on Patients With MGUS and Smoldering Multiple Myeloma | NCT01955395 | Monoclonal Gamm... Smoldering Mult... | Relaxation Resp... | 18 Years - | Massachusetts General Hospital | |
| Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program | NCT05831358 | Multiple Myelom... Monoclonal Gamm... Smoldering Mult... | Multiple Myelom... Multiple Myelom... | 50 Years - | Case Comprehensive Cancer Center | |
| Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma | NCT04850846 | Monoclonal Gamm... Smoldering Mult... | Metformin XR Placebo | 18 Years - | Dana-Farber Cancer Institute | |
| S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS. | NCT00919139 | Multiple Myelom... Smoldering Myel... Waldenstrom's M... Monoclonal Gamm... Amyloidosis | biologic sample... | - | SWOG Cancer Research Network | |
| Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program | NCT05831358 | Multiple Myelom... Monoclonal Gamm... Smoldering Mult... | Multiple Myelom... Multiple Myelom... | 50 Years - | Case Comprehensive Cancer Center | |
| Rituximab in Treating Patients With Peripheral Neuropathy Caused by Monoclonal Gammopathy of Undetermined Significance | NCT00588822 | Precancerous Co... | Rituximab | 21 Years - 90 Years | Mayo Clinic | |
| Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma | NCT02726750 | Monoclonal Gamm... Smoldering Plas... | Biospecimen Col... Laboratory Biom... | 18 Years - | M.D. Anderson Cancer Center | |
| Proteases in Patients With Prostate Cancer That Has Spread to the Bone | NCT00899665 | Anemia Metastatic Canc... Myelodysplastic... Precancerous Co... Prostate Cancer | fluorescence in... microarray anal... molecular diagn... immunohistochem... laboratory biom... biopsy immunoscintigra... | 40 Years - | Barbara Ann Karmanos Cancer Institute | |
| Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma | NCT03119883 | Monoclonal Gamm... Plasma Cell Mye... | 5-Carbon C 13-l... Biospecimen Col... Biospecimen Col... Uniformly-label... | 18 Years - | Mayo Clinic | |
| Iceland Screens, Treats or Prevents Multiple Myeloma | NCT03327597 | Monoclonal Gamm... | Clinical follow... Mental Health a... Standard follow... Clinical follow... Clinical follow... Clinical follow... | 40 Years - | University of Iceland | |
| Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions | NCT05361694 | Multiple Myelom... Smoldering Mult... Monoclonal Gamm... | 18 Years - | University of Miami | ||
| Rituximab in Treating Patients With Peripheral Neuropathy Caused by Monoclonal Gammopathy of Undetermined Significance | NCT00588822 | Precancerous Co... | Rituximab | 21 Years - 90 Years | Mayo Clinic | |
| Natural History Study of Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Myeloma (SMM) | NCT01109407 | Smoldering Myel... Monoclonal Gamm... | 18 Years - | National Institutes of Health Clinical Center (CC) |
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