Spots Global Cancer Trial Database for A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
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Trial Identification
Brief Title: A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
Official Title: A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Therapy After Autologous Stem Cell Transplantation (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) (EXCALIBER-Maintenance)
Study ID: NCT05827016
Conditions
Study Description
Brief Summary: The purpose of this study is to compare the effectiveness of iberdomide maintenance to lenalidomide maintenance therapy after autologous stem cell transplantation (ASCT) in participants with newly diagnosed multiple myeloma (NDMM).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Rocky Mountain Cancer Centers, Aurora, Colorado, United States
Mayo Clinic Florida, Jacksonville, Florida, United States
Local Institution - 0308, Tampa, Florida, United States
Local Institution - 0192, Tampa, Florida, United States
Cleveland Clinic, Weston, Florida, United States
University Cancer Blood Ctr, Athens, Georgia, United States
The Winship Cancer Institute of Emory University, Atlanta, Georgia, United States
Augusta University - Georgia Cancer Center, Augusta, Georgia, United States
The University of Chicago Medical Center - Duchossois Center for Advanced Medicine, Chicago, Illinois, United States
University of Kansas Cancer Center - The Richard and Annette Bloch Cancer Care Pavilion, Westwood, Kansas, United States
Maryland Oncology Hematology, PA- Clinton, Clinton, Maryland, United States
Local Institution - 0279, Worcester, Massachusetts, United States
University of Michigan - Rogel Cancer Center, Ann Arbor, Michigan, United States
Henry Ford Health System - The Henry Ford Cancer Institute (HFCI) - Detroit, Detroit, Michigan, United States
Cancer & Hematology Centers of Western Michigan (CHCWM), Grand Rapids, Michigan, United States
Local Institution - 0303, Rochester, Minnesota, United States
Hattiesburg Clinic - Hematology & Oncology, Hattiesburg, Mississippi, United States
Midwest Oncology Associates - Kansas City, Kansas City, Missouri, United States
Morristown Medical Center, Morristown, New Jersey, United States
Perlmutter Cancer Center at NYU Langone Hematology Oncology Associates-Mineola, Mineola, New York, United States
NYU Langone Health, New York, New York, United States
Columbia University Medical Center - Herbert Irving Pavilion Location, New York, New York, United States
Clinical Research Alliance, Westbury, New York, United States
Novant Health Cancer Institute - Elizabeth, Charlotte, North Carolina, United States
Duke University Hospital, Durham, North Carolina, United States
Novant Health Cancer Institute Hematology - Forsyth, Winston-Salem, North Carolina, United States
Oncology Hematology Care, Inc. - Cincinnati - Galbraith Rd, Cincinnati, Ohio, United States
Cleveland Clinic - Fairview Hospital - Cancer Center (Moll Cancer Center), Cleveland, Ohio, United States
Cleveland Clinic, Cleveland, Ohio, United States
Cleveland Clinic - Hillcrest Hospital - Hillcrest Cancer Center, Mayfield Heights, Ohio, United States
Toledo Clinic Cancer Centers, Toledo, Ohio, United States
Wooster Milltown Specialty and Surgery Center, Wooster, Ohio, United States
Willamette Valley Cancer Institute, Eugene, Oregon, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Local Institution - 0011, Philadelphia, Pennsylvania, United States
University of Pittsburgh - Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
West Cancer Center, Germantown, Tennessee, United States
Tennessee Oncology, Nashville, Tennessee, United States
Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States
UT Southwestern-Harold C. Simmons Cancer Center, Dallas, Texas, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Local Institution - 0259, Mar del Plata, B, Argentina
Local Institution - 0267, Pilar, B, Argentina
Local Institution - 0183, Ciudad Autonoma Buenos Aires, Caba, Argentina
Local Institution - 0227, Ciudad Autonoma Buenos Aires, Caba, Argentina
Local Institution - 0182, Córdoba, , Argentina
Local Institution - 0244, Waratah, New South Wales, Australia
Royal Adelaide Hospital, Adelaide, South Australia, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Local Institution - 0078, Clayton, Victoria, Australia
Ordensklinikum Linz Elisabethinen, Linz, , Austria
Universitätsklinikum St. Pölten, St. Pölten, , Austria
Medizinische Universitaet Wien - Universitaetsklinik fuer Augenheilkunde und Optometrie, Vienna, , Austria
Hanusch-Krankenhaus, Vienna, , Austria
Local Institution - 0035, Charleroi, WHT, Belgium
Local Institution - 0048, Kortrijk, , Belgium
Local Institution - 0245, Curitiba, PR, Brazil
Local Institution - 0214, Niterói, RJ, Brazil
Local Institution - 0082, Rio de Janeiro, RJ, Brazil
Local Institution - 0081, Ribeirão Preto, SP, Brazil
Local Institution - 0277, Sao Paulo, SP, Brazil
Local Institution - 0194, São Paulo, SP, Brazil
Local Institution - 0241, São Paulo, SP, Brazil
Local Institution - 0190, Barretos, , Brazil
Local Institution - 0083, Porto Alegre, , Brazil
Local Institution - 0096, Rio de Janeiro, , Brazil
Local Institution - 0098, Salvador, , Brazil
Cross Cancer Institute, Edmonton, Alberta, Canada
The Ottawa Hospital - General Campus, Ottawa, Ontario, Canada
Local Institution - 0307, Montreal, Quebec, Canada
CHUQ - The Hôtel-Dieu de Québec, Quebec, , Canada
Fundación Arturo López Pérez, Santiago, , Chile
Instituto Oncolologico del Sur, Temuco, , Chile
Clinica Alemana - Vitacura, Vitacura, , Chile
Anhui Provincial Hospital, Hefei, AH, China
Local Institution - 0100, Beijing Shi, Beijing, China
The Fifth Medical Center of People's Liberation Army General Hospital, Beijing, Beijing, China
Local Institution - 0242, Chongqing, Chongqing, China
Guangdong Provincial People's Hospital, Guangzhou Shi, Guangdong, China
Local Institution - 0079, Guangzhou, Guangdong, China
Local Institution - 0304, Guangzhou, Guangdong, China
Local Institution - 0256, Shenzhen, Guangdong, China
Henan Cancer Hospital, Zhengzhou City, Henan, China
Xiangya Hospital, Central South University, Changsha, Hunan, China
Local Institution - 0282, Changsha, Hunan, China
Local Institution - 0266, Nanjing, Jiangsu, China
Local Institution - 0239, Xuzhou, Jiangsu, China
The First Affiliated Hospital of Nanchang University - Donghu District, Nanchang, Jiangxi, China
Local Institution - 0091, Changchun, Jilin, China
Local Institution - 0094, Shenyang, Liaoning, China
Local Institution - 0265, Xi'an City, Shaanxi, China
Local Institution - 0240, Jinan, Shandong, China
Local Institution - 0271, Shanghai, Shanghai, China
Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China
The First Affiliated Hospital - Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Peking University People's Hospital, Beijing, , China
Local Institution - 0212, Binzhou, , China
Local Institution - 0234, Changsha, , China
Local Institution - 0273, Fuzhou, , China
Local Institution - 0231, Nanjing, , China
Local Institution - 0077, Qingdao, , China
Ruijin Hospital Affiliated to The Shanghai Jiao Tong University Medical School, Shanghai, , China
Local Institution - 0305, Suzhou Shi, , China
Wenzhou Medical University - The First Affiliated Hospital, Wenzhou Shi, , China
Local Institution - 0248, Wuhan Shi, , China
Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, , China
Local Institution - 0302, Monteria, Cordoba, Colombia
Local Institution - 0217, Bogota, , Colombia
Local Institution - 0211, Bogota, , Colombia
Local Institution - 0101, Floridablanca, , Colombia
Local Institution - 0179, Medellin, , Colombia
Local Institution - 0093, Valledupar, , Colombia
Fakultní Nemocnice Brno, Brno, , Czechia
Fakultní Nemocnice Olomouc, Olomouc, , Czechia
Fakultní nemocnice Královské Vinohrady, Prague, , Czechia
Všeobecná fakultní nemocnice v Praze, Praha, , Czechia
Odense Universitetshospital, Odense, , Denmark
Helsingin Yliopistollinen Sairaala (HUS) - Syopakeskus (Comprehensive Cancer Center), Helsinki, , Finland
Kuopio University Hospital, Kuopio, , Finland
CHU Hôpital Sud, Amiens Cedex 1, , France
Institut d'Hématologie de Basse-Normandie (IHBN), Caen, , France
Local Institution - 0050, Creteil, , France
Local Institution - 0236, La Roche Sur Yon, , France
Centre Hospitalier Régional Universitaire de Lille (CHRU) - Hôpital Claude Huriez, Lille, , France
CHU Limoges - Hôpital Dupuytren, Limoges, , France
Centre Hospitalier Universitaire de Nantes (CHU de Nantes) - Hotel-Dieu, Nantes, , France
Local Institution - 0219, Paris, , France
Hopital Pitie-Salpetriere, Paris, , France
Local Institution - 0066, Pierre Benite, , France
Institut Universitaire du Cancer de Toulouse - Oncopole, Toulouse, , France
Local Institution - 0037, Berlin, BE, Germany
Universitätsklinikum Ulm, Ulm, BW, Germany
Local Institution - 0298, Erlangen, BY, Germany
Local Institution - 0297, Hamburg, , Germany
St. Barbara-Klinik Hamm-Heessen GmbH, Hamm, , Germany
Universitätsklinikum Jena, Jena, , Germany
Universitätsklinikum Tübingen, Tübingen, , Germany
"General Hospital of Thessaloniki ""G. Papanikolaou""", Thessaloniki, B, Greece
Local Institution - 0097, Rio, G, Greece
Local Institution - 0185, Athina, I, Greece
Alexandra General Hospital of Athens, Athens, , Greece
Local Institution - 0290, Larisa, , Greece
Theageneio Cancer Hospital of Thessaloniki, Thessaloniki, , Greece
Local Institution - 0250, Hong Kong, HK, Hong Kong
Local Institution - 0128, Chandigarh, CH, India
Local Institution - 0110, Bangalore, Karnataka, India
Local Institution - 0109, Cochin, KL, India
Local Institution - 0200, Kolhapur, MH, India
Local Institution - 0152, Nagpur, MH, India
Local Institution - 0123, Pune, MH, India
Local Institution - 0142, Pune, MH, India
Sparsh Hospitals & Critical Care, Bhubaneswar, Odisha, India
Local Institution - 0125, Kolkata, WB, India
Local Institution - 0135, Navi Mumbai, , India
Local Institution - 0057, Ashdod, , Israel
Assaf Harofeh Medical Center, Beer Ya'Aqov, , Israel
Hillel Yaffe Medical Center, Hadera, , Israel
Rambam Medical Center, Haifa, , Israel
Shaare Zedek Medical Center, Jerusalem, , Israel
Hadassah University Medical Center, Jerusalem, , Israel
Local Institution - 0108, Petah Tikva, , Israel
Local Institution - 0131, Ramat Gan, , Israel
Local Institution - 0136, Tel Aviv-Yafo, , Israel
Azienda Ospedaliero Universitaria Policlinico G. Rodolico San Marco - Ospedale San Marco, Catania, CT, Italy
Local Institution - 0306, Firenze, FL, Italy
Local Institution - 0115, Genova, GE, Italy
Local Institution - 0188, Milano, MI, Italy
Local Institution - 0071, Milano, MI, Italy
Azienda Ospedaliero Universitaria Pisana - Ospedale Santa Chiara, Pisa, PI, Italy
Fondazione Policlinico Universitario Agostino Gemelli, Roma, RM, Italy
Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino - Ospedale Molinette, Torino, TO, Italy
"Azienda Ospedaliera Universitaria ""Federico II""", Naples, , Italy
Local Institution - 0278, Pavia, , Italy
Local Institution - 0065, Rome, , Italy
Shonan Kamakura General Hospital, Kamakura-Shi, Kanagawa, Japan
Kumamoto University Hospital, Kumamoto-shi, Kumamoto, Japan
Chiba University Hospital, Chiba-shi, , Japan
Local Institution - 0118, Gifu-Shi, , Japan
Local Institution - 0133, Higashiibaraki-Gun, , Japan
Local Institution - 0112, Hiroshima-shi, , Japan
Tokai University Hospital, Isehara-shi, , Japan
Kagoshima University Hospital, Kagoshima-Shi, , Japan
Kanazawa University Hospital, Kanazawa-shi, , Japan
Local Institution - 0134, Kobe-Shi, , Japan
The Cancer Institute Hospital of Japanese Foundation for Cancer Research (JFCR), Koto-Ku, , Japan
Gunma University Hospital, Maebashi-Shi, , Japan
The Jikei University Hospital, Minato-ku, , Japan
The Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki-Shi, , Japan
Nagoya City University Hospital, Nagoya-Shi, , Japan
Local Institution - 0268, Osakasayama-shi, , Japan
Jichi Medical University Saitama Medical Center, Saitama-shi, , Japan
Local Institution - 0105, Sapporo-shi, , Japan
National Hospital Organization Sendai Medical Center, Sendai-shi, , Japan
Local Institution - 0106, Shibukawa-shi, , Japan
Japanese Red Cross Medical Center, Shibuya-ku, , Japan
Local Institution - 0130, Shizuoka-shi, , Japan
Pusan National University Hospital, Busan, , Korea, Republic of
National Cancer Center, Goyang-si, , Korea, Republic of
Local Institution - 0293, Seongnam-si, Gyeonggi-do, , Korea, Republic of
Local Institution - 0295, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Ulsan University Hospital (UUH), Ulsan, , Korea, Republic of
Local Institution - 0127, Mexico, CMX, Mexico
Local Institution - 0146, Toluca De Lerdo, MEX, Mexico
Local Institution - 0283, Monterrey, NL, Mexico
Local Institution - 0107, Mexico city, , Mexico
Local Institution - 0129, Amsterdam, NH, Netherlands
Local Institution - 0149, Bydgoszcz, KP, Poland
Local Institution - 0059, Lodz, LD, Poland
Local Institution - 0195, Gdansk, PM, Poland
Local Institution - 0252, Gliwice, , Poland
Local Institution - 0039, Katowice, , Poland
Local Institution - 0044, Lublin, , Poland
Local Institution - 0119, Warsaw, , Poland
Unidade Local de Saude Braga, Braga, , Portugal
Local Institution - 0151, Coimbra, , Portugal
Instituto Português Oncologia do Porto Francisco Gentil, EPE, Porto, , Portugal
Institutul Clinic Fundeni, Bucureşti, B, Romania
Local Institution - 0043, Craiova, Dolj, Romania
Institutul Regional de Oncologie Iași, Iasi, IS, Romania
"Institutul Oncologic ""Prof. Dr. Ion Chiricuţă"" Cluj Napoca", Cluj-Napoca, Jud. Cluj, Romania
"Institutul Oncologic ""Prof. Dr. Ion Chiricuţă"" Cluj Napoca", Cluj-Napoca, , Romania
Local Institution - 0138, Singapore, , Singapore
Local Institution - 0187, Singapore, , Singapore
Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
Local Institution - 0226, Barcelona, B, Spain
Hospital San Pedro de Alcántara, Cáceres, CC, Spain
Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Las Palmas, Spain
Hospital Universitario Virgen Arrixaca, Murcia, MU, Spain
Hospital Universitari i Politècnic La Fe, Valencia, VC, Spain
Hospital Universitari Germans Trias i Pujol, Badalona, , Spain
Hospital Universitari Son Espases, Palma de Mallorca, , Spain
Local Institution - 0163, Pamplona, , Spain
Local Institution - 0171, Luleå, BD, Sweden
Södra Älvsborgs Sjukhus, Borås, , Sweden
Local Institution - 0291, Uddevalla, , Sweden
Local Institution - 0168, Aarau 1, , Switzerland
Local Institution - 0153, Kao-Hsiung, , Taiwan
E-DA Cancer Hospital, Kaohsiung, , Taiwan
Far Eastern Memorial Hospital, New Taipei City, , Taiwan
Local Institution - 0165, Tainan, , Taiwan
Local Institution - 0292, Taipei, , Taiwan
Local Institution - 0289, Taoyuan, , Taiwan
Local Institution - 0167, Ankara, , Turkey
Local Institution - 0287, Cankaya, , Turkey
Local Institution - 0052, Edirne, , Turkey
Local Institution - 0068, Istanbul, , Turkey
Local Institution - 0158, Izmir, , Turkey
Local Institution - 0073, Izmir, , Turkey
Local Institution - 0024, Kayseri, , Turkey
Local Institution - 0032, Yenimahalle, , Turkey
NHS Grampian - Aberdeen Royal Infirmary, Aberdeen, ABD, United Kingdom
GenesisCare -Windosr, Windsor, Berkshire, United Kingdom
University Hospitals of Derby and Burton NHS Foundation Trust - Royal Derby Hospital, Derby, DBY, United Kingdom
Local Institution - 0162, Bournemouth, DOR, United Kingdom
Local Institution - 0284, Portsmouth, HAM, United Kingdom
University Hospitals of North Midlands NHS Trust (UHNM) - Royal Stoke University Hospital, Stoke-on-Trent, Staffordshire, United Kingdom
NHS Lothian - Western General Hospital, Edinburgh, , United Kingdom
Barts Health NHS Trust - St Bartholomew's Hospital, London, , United Kingdom
GenesisCare-Oxford, Oxford, , United Kingdom
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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