Spots Global Cancer Trial Database for A Trial Comparing a Prophylactic With a Therapeutic Platelet Transfusion Strategy in Two Groups
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Trial Identification
Brief Title: A Trial Comparing a Prophylactic With a Therapeutic Platelet Transfusion Strategy in Two Groups
Official Title: Prospective Randomized Trial Comparing a Prophylactic With a Therapeutic Platelet Transfusion Strategy in Two Groups: 1)in Patients With Acute Myeloid Leukemia After Intensive Chemotherapy and 2) After Autologous Blood Stem Cell Transplantation
Study ID: NCT00521664
Conditions
Study Description
Brief Summary: The purpose of this study is to show that a therapeutic platelet transfusion strategy (i.e. platelet transfusion only in case of bleeding) needs minimally a quarter less of transfusions compared to the standard prophylactic transfusion strategy (i.e. platelet transfusion without any sign of bleeding when the platelet count is below 10.000/µL). With the experimental transfusion strategy transfusions could be safely reduced when the study hypothesis can be proven. This is the first prospective randomized study on this topic.
Detailed Description:
Eligibility
Minimum Age: 16 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Klinikum Nürnberg Nord; Einheit für Knochenmarktransplantation; 5. Med. Klinik, Nürnberg, , Germany
Contact Details
Name: Gerhard Ehninger, Prof.
Affiliation: University Hospital Carl Gustav Carus Dresden
Role: PRINCIPAL_INVESTIGATOR
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