Spots Global Cancer Trial Database for Nalbuphine Versus Morphine for Perioperative Tumor Ablation
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Trial Identification
Brief Title: Nalbuphine Versus Morphine for Perioperative Tumor Ablation
Official Title: Analgesic Efficacy and Safety of Nalbuphine Versus Morphine for Perioperative Tumor Ablation: a Randomized, Control, Multicentre Trial
Study ID: NCT05073744
Study Description
Brief Summary: This randomized, positive control, multicentre trial is designed to compare the analgesic efficacy and safety of nalbuphine hydrochloride injection and morphine hydrochloride injection for perioperative tumor ablation.
Detailed Description: Sedation and analgesia use in tumor ablation is a necessary part of the procedure. However, the optimal medicine for sedation and analgesia for tumor ablation remains controversial. Currently, morphine is a traditional opioid used for pain control and anaesthesia. As no publications have compared the anaesthetic and analgesic effects between nalbuphine and morphine during tumor ablation, this trial aims to compare the analgesic efficacy and safety of nalbuphine and morphine for perioperative tumor ablation. In addition, other endpoints in term of perioperative analgesia indexes, such as ablation time, daily dose, analgesia satisfaction, quality of life, and safety, etc. will be compared.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Anhui Province Cancer Hospital, Hefei, Anhui, China
The Second Hospital of Anhui Medical University, Hefei, Anhui, China
The First Hospital of Lanzhou University, Lanzhou, Gansu, China
Guangxi Medical University Affiliated Tumor Hospita, Nanning, Guangxi, China
The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China
The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, Guizhou, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Henan Provincial People's Hospital, Zhengzhou, Henan, China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Jingmen NO.2People's Hospital, Jingmen, Hubei, China
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, China
Yichang Central People's Hospital, Yichang, Hubei, China
The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
Zhongda Hospital Southeast University, Nanjing, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China
The First Bethune Hospital of Jilin University, Changchun, Jilin, China
Shengjing Hospital of China Medical University, Shengyang, Liaoning, China
Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai, China
Shanghai Tenth People's Hospital, Shanghai, Shanghai, China
Lishui Municipal Central Hospital, Lishui, Zhejiang, China
Contact Details
Name: Gao-Jun Teng, MD
Affiliation: Zhongda Hospital
Role: PRINCIPAL_INVESTIGATOR
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