Spots Global Cancer Trial Database for Target Volume Delineation After NACT in LA-NPCarcinoma Patients Treated With NACT+ CCRT
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Trial Identification
Brief Title: Target Volume Delineation After NACT in LA-NPCarcinoma Patients Treated With NACT+ CCRT
Official Title: Study on Delineation of the Target Volumes and Determination of the Irradiation Doses in Untreated Nasopharyngeal Carcinoma (NPC) Treated With Intensity Modulated Radiation Therapy (IMRT)
Study ID: NCT03283293
Conditions
Interventions
Study Description
Brief Summary: The gross tumor volumes of the primary site and the neck nodes (GTVnx and GTVnd) could be delineated according to the post-NACT tumor position and receive radical radiation dose, while the tumor disappear after NACT could be encompassed in the first clinical target volume (CTV1) and receive high preventive radiation dose. Through this method,it is more likely to achieve the ultimate goal that maximize the chance of cure while minimize the injury of surrounding normal tissues, maintaining organ function and life quality. Therefore, this stage II clinical trial was designed to study the prognosis and locoregional failure patterns of this target volume delineation method in LA-NPC treated with NACT plus CCRT.
Detailed Description:
Eligibility
Minimum Age: 14 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, China
Contact Details
Name: Chong Zhao
Affiliation: Sun Yat-sen University
Role: PRINCIPAL_INVESTIGATOR
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