Spots Global Cancer Trial Database for The Diagnosis of NPC Using the Probe-based Confocal Laser Endomicroscopy

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Trial Identification

Brief Title: The Diagnosis of NPC Using the Probe-based Confocal Laser Endomicroscopy

Official Title: The Diagnosis of the Squamous Cell Carcinoma in Head and Neck by Using the Probe-based Confocal Laser Endomicroscopy

Study ID: NCT03202173

Conditions

Nasopharyngeal Carcinoma

Squamous Cell Carcinoma of the Head and Neck

Interventions

10% fluorescein

Study Description

Brief Summary: To evaluate the use of probe-based confocal laser endomicroscopy (pCLE) in human nasopharyngeal mucosa for the differentiation of the nasopharyngeal squamous cell carcinomas.

Detailed Description: The aim of this study was to depict the applicability of pCLE examinations for diagnosing NPC in comparison to the gold standard of histopathological examination, as well as developed an easy-to-use and straightforward scoring system for the identification of NPC on the basis of morphological and architectural criteria in order to enable a valid and reproducible CLE assessment even for non-experts in their daily clinical practice.