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Spots Global Cancer Trial Database for squamous cell carcinoma of the head and neck

Every month we try and update this database with for squamous cell carcinoma of the head and neck cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
C-TPF in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and NeckNCT00402545
Head and Neck N...
Cetuximab
Docetaxel
Cisplatin
5-Fluorouracil
18 Years - Dana-Farber Cancer Institute
Study Comparing RT With Cetuximab + Xevinapant to RT With Cetuximab-placebo in Patients With Head and Neck CancerNCT05930938
Squamous Cell C...
Xevinapant
Placebo
cetuximab
IMRT
18 Years - 79 YearsGroupe Oncologie Radiotherapie Tete et Cou
A Phase II Trial of Cetuximab and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck CancerNCT00409565
Head and Neck C...
Squamous Cell C...
Cetuximab
Bevacizumab
18 Years - 98 YearsNational Cancer Institute (NCI)
Sexual Behavior in Head and Neck Cancer PatientsNCT00662662
Oropharyngeal C...
Head and Neck C...
Squamous Cell C...
Questionnaire
18 Years - M.D. Anderson Cancer Center
Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL)NCT03946358
Squamous Cell C...
Anal Canal Canc...
Cervical Cancer
Blood sample co...
Tumor biopsies
CT scan
Atezolizumab
UCPVax
18 Years - 75 YearsCentre Hospitalier Universitaire de Besancon
Hyperbaric Radiation Sensitization of Head and Neck CancersNCT03843671
Squamous Cell C...
Hyperbaric oxyg...
Hyperbaric cham...
18 Years - National Baromedical Services
Brentuximab Vedotin With Pembrolizumab in Metastatic Solid TumorsNCT04609566
Melanoma
Non-small Cell ...
Squamous Cell C...
brentuximab ved...
pembrolizumab
18 Years - Seagen Inc.
Study of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101NCT04144140
Lymphoma
Advanced Solid ...
E7766
18 Years - Eisai Inc.
A Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsNCT03517488
Melanoma
Breast Carcinom...
Hepatocellular ...
Urothelial Carc...
Squamous Cell C...
Renal Cell Carc...
Colorectal Carc...
Non-small Cell ...
Gastric or Gast...
Endometrial Car...
Mesothelioma
Neuroendocrine ...
Cervical Cancer
Small Cell Lung...
Squamous Cell C...
Castration-Resi...
Nasopharyngeal ...
Cholangiocarcin...
Basal Cell Carc...
Ovarian Carcino...
Fallopian Tube ...
Thymoma
Thymic Carcinom...
Squamous Cell C...
Vulvar Carcinom...
Solid Tumors Wi...
Malignant Adnex...
Non-squamous Ce...
XmAb20717
18 Years - Xencor, Inc.
Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHNNCT02124707
Head and Neck C...
Squamous Cell C...
Cetuximab
Paclitaxel
Carboplatin
18 Years - UNC Lineberger Comprehensive Cancer Center
CTC Detection Rate in SCCHN With a in Vivo DeviceNCT03071900
Circulating Tum...
Squamous Cell C...
circulating tum...
20 Years - 90 YearsNanjing Tongren Hospital
Debio 1143-201 Dose-finding and Efficacy Phase I/II TrialNCT02022098
Squamous Cell C...
Cisplatin
Radiotherapy
Debio 1143
Placebo
18 Years - 75 YearsDebiopharm International SA
Nutrition and Life QUality Patients With Head and Neck CancersNCT02510859
Squamous Cell C...
Systematic nutr...
18 Years - University Hospital, Caen
Patient Reported Outcomes Study Using Electronic Monitoring System for Advanced or Metastatic Solid CancerNCT05931445
Breast Cancer
Lung Cancer
Colorectal Canc...
Liver Cancer
Stomach Cancer
Endometrial Can...
Ovarian Cancer
Squamous Cell C...
e-PRO monitorin...
18 Years - Comprehensive Support Project for Oncology Research
Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL)NCT03946358
Squamous Cell C...
Anal Canal Canc...
Cervical Cancer
Blood sample co...
Tumor biopsies
CT scan
Atezolizumab
UCPVax
18 Years - 75 YearsCentre Hospitalier Universitaire de Besancon
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid TumorsNCT03645928
Metastatic Mela...
Squamous Cell C...
Non-small Cell ...
Lifileucel
LN-145
Pembrolizumab
LN-145-S1
Ipilimumab
Nivolumab
12 Years - Iovance Biotherapeutics, Inc.
Pharmacodynamic Study to Assess the Anti-proliferative Activity of the PARP Inhibitor Olaparib in Patients With HPV Positive and HPV Negative HNSCCNCT02686008
Squamous Cell C...
Olaparib
18 Years - Yale University
Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell CarcinomaNCT02296684
Cancer of Head ...
Head and Neck C...
Neoplasms, Head...
Carcinoma, Squa...
Squamous Cell C...
Squamous Cell C...
MK-3475 (neoadj...
Surgery
Intensity modul...
Image-guided ra...
Cisplatin
MK-3475 (adjuva...
Peripheral bloo...
18 Years - Washington University School of Medicine
Study of Dalantercept in Patients With Squamous Cell Carcinoma of the Head and NeckNCT01458392
Squamous Cell C...
Dalantercept
18 Years - Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
Re-irradiation With Fractionated Stereotactic Radiosurgery Plus Cetuximab in Patients With Recurrent Squamous Cell Carcinoma of the Head and NeckNCT01104922
Squamous Cell C...
Cetuximab
Stereotactic ra...
18 Years - University of Pittsburgh
Cetuximab With Radiotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck in Chinese SubjectsNCT01012258
Squamous Cell C...
Cetuximab + con...
18 Years - Merck KGaA, Darmstadt, Germany
Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid TumorsNCT00625456
Melanoma
Lung Cancer
Renal Cell Carc...
Squamous Cell C...
Recombinant Vac...
18 Years - SillaJen, Inc.
A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck CancerNCT00210470
Squamous Cell C...
IRX-2
Cyclophosphamid...
Indomethacin
Zinc
Omeprazole
18 Years - 80 YearsBrooklyn ImmunoTherapeutics, LLC
Definitive Concurrent Hypofractionated Rth With Weekly Cisplatin in Locally Advanced SCCHNNCT03880396
Squamous Cell C...
hypofractionate...
18 Years - 75 YearsAssiut University
Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHNNCT01305772
Squamous Cell C...
Panitumumab
Surgery
Radiation Thera...
18 Years - Duke University
Study of TQB2450 in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck(R/M SCCHN)NCT03855384
Squamous Cell C...
TQB2450+cisplat...
placebo+cisplat...
18 Years - Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
GEN1046 Safety Trial in Patients With Malignant Solid TumorsNCT03917381
Solid Tumors
Non-small Cell ...
Urothelial Carc...
Endometrial Car...
Triple Negative...
Squamous Cell C...
Cervical Cancer
Acasunlimab
Acasunlimab in ...
Acasunlimab in ...
Acasunlimab in ...
18 Years - Genmab
Comparison of Two Concomitant Administration of RT With Cisplatin in Standard Infusion or Fractional InfusionNCT03330249
Squamous Cell C...
Split Cisplatin
Cisplatin
Radiotherapy
18 Years - 70 YearsGroupe Oncologie Radiotherapie Tete et Cou
A Phase I Study to Evaluate the Safety, Tolerability and Efficacy of MEDI4736 (Durvalumab) With Tremelimumab in Head and Neck CancerNCT02262741
Squamous Cell C...
MEDI4736
tremelimumab
18 Years - 99 YearsMedImmune LLC
Ficlatuzumab and Cetuximab in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)NCT02277197
Carcinoma, Squa...
Squamous Cell C...
Squamous Cell C...
Ficlatuzumab
Cetuximab
18 Years - University of Pittsburgh
0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and NeckNCT00257738
Squamous Cell C...
MAGE-A3
HPV-16 vaccine
18 Years - 80 YearsUniversity of Maryland, Baltimore
Mitomycin C in Patients With Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Standard TherapiesNCT02369458
Squamous Cell C...
Squamous Cell C...
Mitomycin-C
Pegfilgrastim
18 Years - Washington University School of Medicine
Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck PatientsNCT02139020
Squamous Cell C...
Plasma samples
18 Years - Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Patritumab With Cetuximab and a Platinum Containing Therapy for Patients With Head and Neck CancerNCT02350712
Squamous Cell C...
Patritumab
Cetuximab
Cisplatin
Carboplatin
18 Years - Daiichi Sankyo
Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)NCT00652613
Squamous Cell C...
3 Dimensional R...
Intensity Modul...
18 Years - 65 YearsTata Memorial Hospital
Addition of SNS-301 to Checkpoint Inhibitor Treatment in Metastatic/Recurrent SCCHNNCT04034225
Squamous Cell C...
SNS-301
Pembrolizumab
18 Years - Sensei Biotherapeutics, Inc.
A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced CancersNCT05544929
Carcinoma, Non-...
Cutaneous Melan...
Carcinoma, Rena...
Carcinoma, Ovar...
Nasopharyngeal ...
Carcinoma, Thym...
Anal Cancer
Mesothelioma
Esophagogastric...
High Microsatel...
Squamous Cell C...
Triple Negative...
KFA115
pembrolizumab
18 Years - Novartis
The Addition of Pembrolizumab to Postoperative Radiotherapy in Cutaneous Squamous Cell Cancer of the Head and NeckNCT03057613
Squamous Cell C...
Pembrolizumab
IMRT 60-66Gy
18 Years - Case Comprehensive Cancer Center
Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior ImmunotherapyNCT04326257
Squamous Cell C...
Nivolumab+Relat...
Nivolumab+Ipili...
18 Years - University of Pittsburgh
Study of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101NCT04144140
Lymphoma
Advanced Solid ...
E7766
18 Years - Eisai Inc.
Valproic Acid Plus Cisplatin and Cetuximab in Recurrent and/or Metastatic Squamous Cell Carcinoma of Head and NeckNCT02624128
Squamous Cell C...
Valproic Acid
Cisplatin
Cetuximab
18 Years - National Cancer Institute, Naples
The Role of Chromoendoscopy in the Early Detection of Esophageal Cancer in Patients With Prior Head and Neck CancersNCT02435602
Esophageal Squa...
Squamous Cell C...
NBI endoscopy
Lugol chromoend...
18 Years - Maria Sklodowska-Curie National Research Institute of Oncology
Expansion Trial for Axitinib In Head And Neck CancerNCT02762513
Squamous Cell C...
Axitinib
18 Years - University of Michigan Rogel Cancer Center
Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.NCT03525392
Pancreatic Duct...
Colorectal Canc...
Gastric Cancer
Squamous Cell C...
Bone Cancer
Advanced Cancer
Recurrent Disea...
Metastatic Tumo...
177Lu-3BP-227 (...
18 Years - Ipsen
Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous TumorNCT00377247
Primary Advance...
Squamous Cell C...
autologous mono...
37 Years - University of Pittsburgh
Clinical Study of Pan-cancer DNA Methylation Test in PlasmaNCT05685524
Cancer
DNA methylation...
18 Years - 80 YearsWuhan Ammunition Life-tech Co., Ltd
Zalutumumab Pharmacokinetics (PK) in Squamous Cell Carcinoma of the Head and Neck (SCCHN)NCT01054625
Head and Neck C...
zalutumumab
18 Years - Genmab
Study of HLA-DR in Cell Cultures Isolated From Primary Squamous Cell CarcinomaNCT06041464
Squamous Cell C...
Cancer
cell culture
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study of Olaparib With Radiation Therapy and Cetuximab in Advanced Head and Neck Cancer With Heavy Smoking HistoryNCT01758731
Squamous Cell C...
Olaparib
Cetuximab
Radiation Thera...
18 Years - University of Colorado, Denver
Prevalence of Liver Fibrosis and Cirrhosis in Patients With Squamous Cell Carcinoma of the Head and NeckNCT03139058
Liver Fibroses
Liver Cirrhoses
Squamous Cell C...
Evaluation of t...
18 Years - Centre Hospitalier Universitaire, Amiens
Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid TumorsNCT03006887
Solid Tumors
lenvatinib
pembrolizumab
20 Years - Eisai Inc.
Study of LN-145/LN-145-S1 Autologous Tumor Infiltrating Lymphocytes in the Treatment of Squamous Cell Carcinoma of the Head & NeckNCT03083873
Squamous Cell C...
LN-145
LN-145-S1
18 Years - Iovance Biotherapeutics, Inc.
GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer PatientsNCT02575404
Melanoma
Non-Small Cell ...
Squamous Cell C...
GR-MD-02
Pembrolizumab
18 Years - Providence Health & Services
Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors.NCT04152018
Squamous Cell C...
Renal Cell Carc...
Ovarian Cancer
Gastric Cancer
Esophageal Canc...
Lung Squamous C...
Pancreatic Canc...
Bile Duct Cance...
Endometrial Can...
Melanoma Cancer
Urothelial Canc...
PF-06940434
PF-06801591
18 Years - Pfizer
Study of Proxinium for Treating Patients With Squamous Cell Head and Neck CancerNCT00272181
Squamous Cell C...
Carcinoma, Squa...
Neoplasms, Squa...
Head and Neck N...
Mouth Neoplasms
Head and Neck C...
Proxinium
18 Years - Sesen Bio, Inc.
Chemotherapy With Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck CancerNCT01289522
Squamous Cell H...
Recurrent or Me...
cetuximab IV
Biopsies
18 Years - 70 YearsGroupe Oncologie Radiotherapie Tete et Cou
Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical ResectionNCT01927744
Head and Neck C...
Docetaxel
Erlotinib
Placebo
Questionnaires
Phone Call
Chemotherapy
18 Years - M.D. Anderson Cancer Center
Trial of 2 Cycles of Induction Chemo With Abraxane, Cetuximab, Cisplatin, & 5-FU for Advanced Head and Neck CancerNCT00736944
Squamous Cell C...
Abraxane
Cetuximab
Cetuximab
Cisplatin
5-FU
Radiation (Post...
Cisplatin
Cetuximab
18 Years - Washington University School of Medicine
A Study of SGN-PDL1V in Advanced Solid TumorsNCT05208762
Carcinoma, Non-...
Squamous Cell C...
Esophageal Squa...
Ovarian Neoplas...
Melanoma
Triple Negative...
Gastric Cancer
SGN-PDL1V
pembrolizumab
18 Years - Seagen Inc.
ERBITUX® Followed by Adjuvant Treatment With Chemoradiation and ERBITUX® for Locally Advanced Head and Neck Squamous Cell CarcinomaNCT01218048
Squamous Cell C...
Cetuximab
Surgery
Post-surgical r...
Cisplatin or ca...
18 Years - University of Pittsburgh
Definitive Concurrent Hypofractionated Rth With Weekly Cisplatin in Locally Advanced SCCHNNCT03880396
Squamous Cell C...
hypofractionate...
18 Years - 75 YearsAssiut University
Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck CancerNCT03733210
Squamous Cell C...
Carcinoma of th...
Panitumumab-IRD...
89-Zirconium (Z...
Pinpoint IR IR9...
SPY-PHI IR9000 ...
Explorer Air ca...
PDE-NEO II came...
FIS-00 fluoresc...
Da Vinci Firefl...
IGP-ELVIS-v4 Ma...
Vevo 3100 LAZR-...
Pearl Triology ...
Odyssey CLx Ima...
Leica fluoresce...
19 Years - Stanford University
SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene and/or PI-3 Kinase Pathway GenesNCT02644122
Metastatic Squa...
SF1126
18 Years - University of California, San Diego
Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck RegionNCT05482880
Cutaneous Squam...
Cutaneous Squam...
Squamous Cell C...
Squamous Cell C...
Squamous Cell C...
Squamous Cell C...
Skin Cancer
High-Risk Cance...
Quality of Life
Satisfaction, P...
Regular care wi...
18 Years - Maastricht University Medical Center
CIML NK Cell in Head & Neck CancerNCT04290546
Squamous Cell C...
Recurrent Head ...
Interleukin-15 ...
CIML NK cell In...
Ipilimumab
Cetuximab
18 Years - Dana-Farber Cancer Institute
A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay StudyNCT02841748
Head and Neck C...
Squamous Cell C...
Pembrolizumab
Placebo
18 Years - University of Chicago
Phase II Study of RAD001 Head and Neck CancerNCT01051791
Squamous Cell C...
Everolimus 10mg...
18 Years - 80 YearsUniversity of Pittsburgh
Hemopurifier Plus Pembrolizumab in Head and Neck CancerNCT04453046
Squamous Cell C...
Hemopurifier
Pembrolizumab 2...
18 Years - Aethlon Medical Inc.
Safety and Efficacy of Radiation/Cetuximab Plus EGFR Antisense DNA for Head and Neck Squamous Cell CarcinomaNCT00903461
Carcinoma, Squa...
Squamous Cell C...
Squamous Cell C...
EGFR Antisense ...
18 Years - University of Pittsburgh
A Study of SGN-PDL1V in Advanced Solid TumorsNCT05208762
Carcinoma, Non-...
Squamous Cell C...
Esophageal Squa...
Ovarian Neoplas...
Melanoma
Triple Negative...
Gastric Cancer
SGN-PDL1V
pembrolizumab
18 Years - Seagen Inc.
A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid TumorsNCT02452424
Melanoma
Non-small Cell ...
Squamous Cell C...
Gastrointestina...
Ovarian Cancer
PLX3397
Pembrolizumab
18 Years - Daiichi Sankyo
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid TumorsNCT03645928
Metastatic Mela...
Squamous Cell C...
Non-small Cell ...
Lifileucel
LN-145
Pembrolizumab
LN-145-S1
Ipilimumab
Nivolumab
12 Years - Iovance Biotherapeutics, Inc.
Needs and Preferences of Patients With Head-neck Cutaneous SCCNCT06046625
Cutaneous Squam...
Cutaneous Squam...
Squamous Cell C...
Squamous Cell C...
Squamous Cell C...
Skin Cancer
Patient Satisfa...
High-Risk Cance...
Preference, Pat...
Decision Making
Interview
Regular care wi...
18 Years - Maastricht University Medical Center
Immunotherapy Study of Evofosfamide in Combination With IpilimumabNCT03098160
Pancreatic Canc...
Melanoma
Squamous Cell C...
Prostate Cancer
Evofosfamide
Ipilimumab
18 Years - Threshold Pharmaceuticals
Stereotactic Body Radiotherapy for Head and Neck TumorsNCT01344356
Squamous Cell C...
Nasopharyngeal ...
Salivary Gland ...
Head and Neck S...
Paraganglioma o...
Chordoma of Hea...
Chondrosarcoma ...
Angiofibroma of...
stereotactic bo...
Stereotactic bo...
18 Years - Mercy Research
A Study of Duvelisib in Combination With Pembrolizumab in Head and Neck CancerNCT04193293
Head and Neck S...
Duvelisib
Pembrolizumab
18 Years - SecuraBio
Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and NeckNCT02158234
Squamous Cell C...
Cisplatin
Stereotactic Bo...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
C-TPF in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and NeckNCT00402545
Head and Neck N...
Cetuximab
Docetaxel
Cisplatin
5-Fluorouracil
18 Years - Dana-Farber Cancer Institute
IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid TumorsNCT03758781
Metastatic Canc...
Recurrent Cance...
Solid Tumor
Renal Cell Carc...
Urothelial Carc...
NSCLC
Squamous Cell C...
Non-Small Cell ...
Squamous Cell C...
IRX 2
Nivolumab
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Impact of Ribociclib on Head and Neck Squamous Cell CancerNCT03179956
Squamous Cell C...
Ribociclib
18 Years - Fox Chase Cancer Center
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