Spots Global Cancer Trial Database for Phase Ⅱ Study of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage Ⅲ Nasopharyngeal Carcinoma
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Trial Identification
Brief Title: Phase Ⅱ Study of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage Ⅲ Nasopharyngeal Carcinoma
Official Title: Phase Ⅱ Study of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage Ⅲ Nasopharyngeal Carcinoma
Study ID: NCT00816855
Conditions
Interventions
Study Description
Brief Summary: The primary objective of this study is to determine the tolerance and overall survival in patients with stage Ⅲ NPC treated with neoadjuvant chemotherapy and concurrent chemoradiation. Secondary objectives of the study are to evaluate the distant metastases free survival, and disease-free survival of patients with stage Ⅲ treated with this regimen.
Detailed Description: Concurrent chemoradiation is the standard treatment for locally advanced NPC. The survival benefit gained from adding neoadjuvant chemotherapy to concurrent chemoradiation has never been defined. In the present trail, we hope to assess the tolerance and survival benefits of neoadjuvant chemotherapy followed by concurrent chemoradiation in patients with stage Ⅲ NPC.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Radiation Oncology, Cancer Hospital, Fudan University, Shanghai, , China
Contact Details
Name: Lin Kong, MD
Affiliation: Department of Radiation Oncology, Cancer Hospital, Fudan University
Role: PRINCIPAL_INVESTIGATOR
Name: Chaosu Hu, MD
Affiliation: Department of Radiation Oncology, Cancer Hospital, Fudan University
Role: PRINCIPAL_INVESTIGATOR
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