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Brief Title: Study For Patients With Untreated Gastric Cancer Who Will Receive Capecitabine And Lapatinib
Official Title: An Exploratory, Phase II Trial to Determine the Association of Lapatinib Induced Fluoropyrimidine Gene Changes With Efficacy Parameters of Lapatinib and Capecitabine in First Line Gastric Cancer
Study ID: NCT00526669
Brief Summary: The study will determine if changes in expression of markers involved in the 5-FU pathways are associated with response to treatment with the combination of lapatinib and capecitabine independent of tumor erbB2 status.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
GSK Investigational Site, Loma Linda, California, United States
GSK Investigational Site, Los Angeles, California, United States
GSK Investigational Site, Washington, District of Columbia, United States
GSK Investigational Site, Shreveport, Louisiana, United States
GSK Investigational Site, Ann Arbor, Michigan, United States
GSK Investigational Site, Southgate, Michigan, United States
GSK Investigational Site, Jefferson City, Missouri, United States
GSK Investigational Site, Dallas, Texas, United States
GSK Investigational Site, Montreal, Quebec, Canada
GSK Investigational Site, Hwasun, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Suwon, Gyeonggi-do, , Korea, Republic of
GSK Investigational Site, Mexico City, , Mexico
GSK Investigational Site, Astrakhan, , Russian Federation
GSK Investigational Site, Chelyabinsk, , Russian Federation
GSK Investigational Site, St. Petersburg, , Russian Federation
GSK Investigational Site, Ufa,, , Russian Federation
GSK Investigational Site, Changhua, , Taiwan
GSK Investigational Site, Taipei, , Taiwan
GSK Investigational Site, Taipei, , Taiwan
GSK Investigational Site, Taipei, , Taiwan
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR