Spots Global Cancer Trial Database for tumor biopsy
Every month we try and update this database with for tumor biopsy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) | NCT05634707 | Primary Brain T... Brain Tumor, Re... | Fluoxetine Temozolomide | 24 Years - | Duke University | |
| PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer | NCT01723774 | Breast Neoplasm... | PD0332991 Anastrozole Goserelin Surgery (standa... Tumor biopsy | 18 Years - | Washington University School of Medicine | |
| Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers | NCT00568490 | Head and Neck C... Lung Cancer Lip Cancer Lip Neoplasms Head and Neck C... | Tumor biopsy Phlebotomy | 18 Years - | Stanford University | |
| Minimal Residual Disease in Peripheral T-cell Lymphoma | NCT03297697 | Peripheral T Ce... | Tumor biopsy Peripheral bloo... Lymphotrack TCR... | 18 Years - | Washington University School of Medicine | |
| Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma | NCT04331041 | Pancreas Cancer Cancer of the P... Pancreas Adenoc... | Adaptive stereo... Defactinib Tumor biopsy Research blood ... | 18 Years - | Washington University School of Medicine | |
| Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers | NCT00568490 | Head and Neck C... Lung Cancer Lip Cancer Lip Neoplasms Head and Neck C... | Tumor biopsy Phlebotomy | 18 Years - | Stanford University | |
| BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer | NCT02608229 | Pancreatic Canc... Cancer of Pancr... Cancer of the P... Pancreas Cancer | BVD-523 Nab-paclitaxel Gemcitabine Tumor biopsy | 18 Years - | Washington University School of Medicine | |
| Variations of Immune Infiltrate and Cell Plasticity Markers in Treated Metastatic Melanoma Patients | NCT05029791 | Melanoma | Tumor biopsy Blood sample | 18 Years - | Hospices Civils de Lyon | |
| Long-term Follow-up of Subjects Treated With CARv3-TEAM-E T Cells | NCT05024175 | Glioblastoma Re... Newly Diagnosed... Recurrent Gliob... | Disease assessm... Tumor Biopsy Blood test | 18 Years - | Massachusetts General Hospital | |
| Tumor Phenotypes and Correlation to Clinical Outcomes in Cancer | NCT00283530 | Cancer | Tumor biopsy | 18 Years - | Kentuckiana Cancer Institute | |
| Changes in Phenotype and Genotype of Breast Cancers During the Metastatic Process and Optimization of Therapeutic Targeting (ESOPE) | NCT01956552 | Metastatic Brea... | biopsy or cytop... | 18 Years - | Institut Curie | |
| Study of Sunitinib in Subjects With High Risk Renal Cell Carcinoma | NCT01070186 | Renal Cell Carc... | Sunitinib Tumor biopsy Nephrectomy Biomarkers | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Consistency Between Treatment Responses in PDO Models and Clinical Outcomes in Gastric Cancer | NCT05203549 | Gastric Cancer | Tumor biopsy | 18 Years - 70 Years | D1 Medical Technology (Shanghai) Co., Ltd, China | |
| Biopsies of Cancer Patients for Tumor Molecular Characterization | NCT01061944 | Cancer Metastatic Canc... | 18 Years - | Massachusetts General Hospital | ||
| PS-341 in Treating Patients With Metastatic Kidney Cancer | NCT00025376 | Kidney Cancer | PS-341 Tumor Biopsy | 18 Years - | University of Chicago | |
| Immune Resistance Interrogation Study | NCT04243720 | Cancer Solid Tumor Metastatic Canc... Immune Resistan... | 18 Years - | University Health Network, Toronto | ||
| Biopsies of Cancer Patients for Tumor Molecular Characterization | NCT01061944 | Cancer Metastatic Canc... | 18 Years - | Massachusetts General Hospital | ||
| SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients | NCT04067115 | Ewing Sarcoma | Trabectedin 1 M... Irinotecan tumor biopsy 3'-Deoxy-3'-18F... | 6 Years - 99 Years | Sarcoma Alliance for Research through Collaboration | |
| Long-term Follow-up of Subjects Treated With CARv3-TEAM-E T Cells | NCT05024175 | Glioblastoma Re... Newly Diagnosed... Recurrent Gliob... | Disease assessm... Tumor Biopsy Blood test | 18 Years - | Massachusetts General Hospital | |
| Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies. | NCT01636908 | Cancer Advanced Solid ... | Sunitinib Sorafenib Erlotinib Everolimus Lapatinib Dasatinib Pazopanib Vemurafenib tumor biopsy skin biopsy (op... | 18 Years - | Amsterdam UMC, location VUmc | |
| Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy | NCT03655444 | Head and Neck S... | Abemaciclib Nivolumab Tumor biopsy Peripheral bloo... EORTC QLQ-30 | 18 Years - | Washington University School of Medicine | |
| ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer | NCT03449901 | Soft Tissue Sar... | pegylated argin... Gemcitabine Docetaxel Tumor biopsy Research blood ... | 10 Years - | Washington University School of Medicine | |
| Prospective Collection of Tumor Biopsy and Plasma Samples From Cancer Patients Treated With Molecular Targeted Therapies or Immunotherapy | NCT03835520 | Cancer | Immunotherapeut... Molecular Targe... | 18 Years - | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
| Consistency Between Treatment Responses in PDO Models and Clinical Outcomes in Gastric Cancer | NCT05203549 | Gastric Cancer | Tumor biopsy | 18 Years - 70 Years | D1 Medical Technology (Shanghai) Co., Ltd, China | |
| Neratinib +/- Fulvestrant in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer | NCT01670877 | Breast Neoplasm... | Neratinib Fulvestrant Trastuzumab Tumor biopsy Research blood ... | 18 Years - | Washington University School of Medicine | |
| IL2 Imaging in Metastatic Melanoma | NCT02922283 | Melanoma | IL2-PET scan Tumor biopsy CT scan Biopsy of non-t... | 18 Years - | University Medical Center Groningen | |
| Autoguide Positioning Device for Multiple Stereotactic Biopsies | NCT06306118 | Multiple Stereo... | Multiple stereo... | 18 Years - 80 Years | Medical University of Graz | |
| Identification of Individual Histological and Blood Markers in Patients With Recurrent or Metastatic Upper Aerodigestive Tract Squamous Cell Carcinoma in Response to Immunotherapies | NCT06061705 | Squamous Cell C... | Tumor Biopsy | 18 Years - | Fondation Hôpital Saint-Joseph | |
| Safety and Tolerability of Intravenous Administration of ICVB-1042 | NCT05904236 | Patients With A... | Treatment with ... | 18 Years - | IconOVir Bio | |
| The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) | NCT06146738 | Glioblastoma Glioblastoma Mu... Glioblastoma, I... Glioblastoma Mu... | Palliative Care Tumor biopsy Tumor resection | 18 Years - 90 Years | Erasmus Medical Center | |
| Safety and Tolerability of Intravenous Administration of ICVB-1042 | NCT05904236 | Patients With A... | Treatment with ... | 18 Years - | IconOVir Bio | |
| ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer | NCT03449901 | Soft Tissue Sar... | pegylated argin... Gemcitabine Docetaxel Tumor biopsy Research blood ... | 10 Years - | Washington University School of Medicine | |
| Chemotherapy and Maximal Tumor Debulking of Multi-organ Colorectal Cancer Metastases | NCT01792934 | Multi-organ Met... | XELOX regimen a... FOLFOX regimen ... Surgery radiofrequency ... transarterial c... stereotactic bo... Bevacizumab tumor biopsy | 18 Years - | Radboud University Medical Center | |
| Neoadjuvant Nivolumab and Chemotherapy in Patients With Localized Triple-negative Breast Cancer | NCT04331067 | Triple Negative... | Paclitaxel Carboplatin Nivolumab Cabiralizumab Tumor biopsy Bone marrow Blood draw | 18 Years - | Washington University School of Medicine | |
| The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) | NCT06146738 | Glioblastoma Glioblastoma Mu... Glioblastoma, I... Glioblastoma Mu... | Palliative Care Tumor biopsy Tumor resection | 18 Years - 90 Years | Erasmus Medical Center | |
| Copenhagen Prospective Personalized Oncology (CoPPO) | NCT02290522 | Unspecified Adu... | Tumor biopsy | 18 Years - | Rigshospitalet, Denmark | |
| BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer | NCT02608229 | Pancreatic Canc... Cancer of Pancr... Cancer of the P... Pancreas Cancer | BVD-523 Nab-paclitaxel Gemcitabine Tumor biopsy | 18 Years - | Washington University School of Medicine | |
| Innovation for Standard Identification of Insertional HPV Mutations and of Target Therapeutic Genes in Cervical Cancer: Towards Development of Personalized Biomarkers in Clinical Oncology | NCT02554565 | Cervical Cancer | Tumor biopsy Blood sampling | 18 Years - | Institut Curie | |
| Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers | NCT03134027 | Genito Urinary ... Bladder Cancer Kidney Cancer Prostate Cancer | Bone marrow bio... Tumor biopsy | 18 Years - | Duke University | |
| Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma | NCT04331041 | Pancreas Cancer Cancer of the P... Pancreas Adenoc... | Adaptive stereo... Defactinib Tumor biopsy Research blood ... | 18 Years - | Washington University School of Medicine | |
| Unusual Toxicity Induced by Radiotherapy | NCT03980977 | Cancer | skin biopsy tumor biopsy blood sample | 2 Years - | Institut de Cancérologie de Lorraine | |
| BATTLE Program: Umbrella Protocol for Patients With Non-Small Cell Lung Cancer (NSCLC) | NCT00409968 | Lung Cancer | Tumor Biopsy | 18 Years - | M.D. Anderson Cancer Center | |
| Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy | NCT03655444 | Head and Neck S... | Abemaciclib Nivolumab Tumor biopsy Peripheral bloo... EORTC QLQ-30 | 18 Years - | Washington University School of Medicine | |
| Copenhagen Prospective Personalized Oncology (CoPPO) | NCT02290522 | Unspecified Adu... | Tumor biopsy | 18 Years - | Rigshospitalet, Denmark | |
| Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy | NCT03655444 | Head and Neck S... | Abemaciclib Nivolumab Tumor biopsy Peripheral bloo... EORTC QLQ-30 | 18 Years - | Washington University School of Medicine | |
| ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer | NCT03449901 | Soft Tissue Sar... | pegylated argin... Gemcitabine Docetaxel Tumor biopsy Research blood ... | 10 Years - | Washington University School of Medicine | |
| Biopsy of Human Tumors for Cancer Stem Cell Characterization: a Feasibility Study | NCT00610415 | Head and Neck C... Head and Neck C... | tumor biopsy | 18 Years - | Stanford University | |
| The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) | NCT06146738 | Glioblastoma Glioblastoma Mu... Glioblastoma, I... Glioblastoma Mu... | Palliative Care Tumor biopsy Tumor resection | 18 Years - 90 Years | Erasmus Medical Center | |
| PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer | NCT01723774 | Breast Neoplasm... | PD0332991 Anastrozole Goserelin Surgery (standa... Tumor biopsy | 18 Years - | Washington University School of Medicine | |
| Los Tres Paso: Neoadjuvant Palbociclib Monotherapy, Concurrent Chemoradiation Therapy, Adjuvant Palbociclib Monotherapy in Patients With p16INK4a Negative, HPV-Unrelated Head and Neck Squamous Cell Carcinoma | NCT03389477 | Head and Neck S... | Palbociclib Cetuximab Cisplatin Intensity-Modul... Tumor biopsy Peripheral bloo... | 18 Years - | Washington University School of Medicine | |
| Study For Patients With Untreated Gastric Cancer Who Will Receive Capecitabine And Lapatinib | NCT00526669 | Neoplasms, Gast... | Lapatinib and C... | 18 Years - | GlaxoSmithKline | |
| Molecular Disease Characterization Initiative (MDCI) | NCT04772053 | Lung Cancer, No... Neoplasms | Tumor biopsy | 18 Years - | GlaxoSmithKline | |
| Celecoxib, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery | NCT00336960 | Colorectal Canc... | celecoxib fluorouracil conventional su... radiation thera... tumor biopsy laboratory biom... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Long-term Follow-up of Subjects Treated With CARv3-TEAM-E T Cells | NCT05024175 | Glioblastoma Re... Newly Diagnosed... Recurrent Gliob... | Disease assessm... Tumor Biopsy Blood test | 18 Years - | Massachusetts General Hospital | |
| The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202) | NCT06146725 | Glioblastoma Glioblastoma, I... Glioblastoma Mu... Glioblastoma Mu... Glioblastoma Mu... | Tumor resection Tumor biopsy | 18 Years - 90 Years | Erasmus Medical Center | |
| Translational Analysis In Longitudinal Series of Ovarian Cancer ORganoids | NCT04555473 | Organoids Epithelial Ovar... | Tumor biopsy | 18 Years - 75 Years | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
| Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer | NCT03532217 | Metastatic Horm... | PROSTVAC-V PROSTVAC-F Nivolumab Ipilimumab Neoantigen DNA ... TriGrid Deliver... Tumor biopsy Peripheral bloo... Fecal samples Leukapheresis | 18 Years - | Washington University School of Medicine |
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