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Brief Title: Study Assessing Safety and Tolerability of AZD8931 Alone or in Combination With Paclitaxel in Japanese Patients.
Official Title: A Phase I, Open-label, Multiple-dose, Dose-escalation Study To Assess the Safety and Tolerability of AZD8931 Monotherapy in Japanese Patients With Advanced Solid Malignancies and in Combination With Paclitaxel in Japanese Female Patients With Advanced Breast Cancer
Study ID: NCT01003158
Brief Summary: The main purpose of this study is to determine if AZD8931 can be safely administered in Japanese patients alone and in combination with weekly paclitaxel. The study will be conducted in two parts: a monotherapy and a combination part, where safe doses of study treatment will be determined.
Detailed Description:
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Osaka, , Japan
Name: Mary Stuart, Dr.
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR
Name: Takayasu Kurata, Dr.
Affiliation: Kinki University School of Medicine
Role: PRINCIPAL_INVESTIGATOR