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Brief Title: Radiofrequency Ablation of Malignant Pulmonary Nodules
Official Title: Efficacy and Safety of Radiofrequency Ablation of Malignant Pulmonary Nodules
Study ID: NCT02629978
Brief Summary: The objective of this study is to evaluate the outcomes of radiofrequency ablation in the treatment of patients with malignant pulmonary nodules(not exceed 3cm )who are not suitable candidates for or refuse surgical resection.
Detailed Description: Percutaneous radiofrequency ablation (RFA) is a minimally invasive technique widely used to treat solid tumors. Patients with malignant pulmonary nodules will undergo a series of CT- guided percutaneous RFA procedures. During the procedures,percutaneous needles will be inserted into the target tissues under CT guidance,the needles deliver thermal energy and then destroy the tumors by causing coagulation necrosis via tissue heating. The purpose of this study is to assess the effectiveness and safety of RFA in pulmonary nodules (maximum tumor diameter ≦30 mm) was 10 mm apart from the big trachea, primary bronchi, esophagus, great vessels,heart and pleura. Preoperative and postoperative evaluations,including recent laboratory tests evaluated and imaging studies reviewed,will be performed both before and after the procedures.
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The Chinese PLA General Hospital, Beijing, , China
Name: Yueyong Xiao
Affiliation: The Chinese PLA General Hospital
Role: PRINCIPAL_INVESTIGATOR