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Spots Global Cancer Trial Database for Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Official Title: A Phase III Double Blind Trial of Oral Duloxetine for Treatment of Pain Associated With Chemotherapy-Induced Peripheral Neuropathy

Study ID: NCT00489411

Study Description

Brief Summary: RATIONALE: Duloxetine may lessen peripheral neuropathy caused by chemotherapy. It is not yet known whether duloxetine is more effective than a placebo in treating peripheral neuropathy caused by chemotherapy. PURPOSE: This randomized phase III trial is studying duloxetine to see how well it works compared with a placebo in treating peripheral neuropathy caused by chemotherapy in patients with cancer.

Detailed Description: OBJECTIVES: Primary * Determine the efficacy of duloxetine hydrochloride in cancer patients with painful chemotherapy-induced (taxane or platinum agent) peripheral neuropathy. Secondary * Determine the influence of this drug on peripheral neuropathy-related functional status and quality of life of these patients. * Describe the differences in duloxetine hydrochloride efficacy when used to treat pain caused by chemotherapy-induced peripheral neuropathy based on the neurotoxic drug and class. OUTLINE: This is a randomized, double-blind, placebo-controlled, crossover study. Patients are stratified according to prior neurotoxic agent (paclitaxel vs oxaliplatin vs other taxane agents without paclitaxel vs platinum agents \[cisplatin\] without oxaliplatin) and high risk for developing painful chemotherapy-induced peripheral neuropathy (no vs yes). Patients are randomized to 1 of 2 treatment arms. * Arm I: Patients receive oral duloxetine hydrochloride once or twice daily in weeks 1-6. After a 1-week rest period, patients cross over to receive an oral placebo once or twice daily in weeks 8-13. * Arm II: Patients receive an oral placebo once or twice daily in weeks 1-6. After a 1-week rest period, patients cross over to receive oral duloxetine hydrochloride once or twice daily in weeks 8-13. Patients complete pain and quality of life questionnaires, including the BPI-SF once weekly and FACT/GOG-NTX and EORTC QLQ-C30 questionnaires, in weeks 1, 6, 8, and 13. After completion of study treatment, patients are followed for 2 weeks.

Eligibility

Minimum Age: 25 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Kaiser Permanente - Deer Valley, Antioch, California, United States

Alta Bates Summit Comprehensive Cancer Center, Berkeley, California, United States

Peninsula Medical Center, Burlingame, California, United States

East Bay Radiation Oncology Center, Castro Valley, California, United States

Valley Medical Oncology Consultants - Castro Valley, Castro Valley, California, United States

Cancer Care Center at John Muir Health - Concord Campus, Concord, California, United States

Kaiser Permanente - Fremont, Fremont, California, United States

Valley Medical Oncology, Fremont, California, United States

Glendale Memorial Hospital Comprehensive Cancer Center, Glendale, California, United States

Kaiser Permanente Medical Center - Hayward, Hayward, California, United States

Rebecca and John Moores UCSD Cancer Center, La Jolla, California, United States

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

Contra Costa Regional Medical Center, Martinez, California, United States

Camino Medical Group - Treatment Center, Mountain View, California, United States

El Camino Hospital Cancer Center, Mountain View, California, United States

Highland General Hospital, Oakland, California, United States

Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States

Bay Area Breast Surgeons, Incorporated, Oakland, California, United States

CCOP - Bay Area Tumor Institute, Oakland, California, United States

Larry G Strieff MD Medical Corporation, Oakland, California, United States

Tom K Lee, Incorporated, Oakland, California, United States

Kaiser Permanente - Division of Research - Oakland, Oakland, California, United States

Kaiser Permanente Medical Center - Oakland, Oakland, California, United States

Palo Alto Medical Foundation, Palo Alto, California, United States

, Pismo Beach, California, United States

Kaiser Permanente Medical Center - Rancho Cordova, Rancho Cardova, California, United States

Kaiser Permanente Medical Center - Redwood City, Redwood City, California, United States

Kaiser Permanente Medical Center - Richmond, Richmond, California, United States

Rohnert Park Cancer Center, Rohnert Park, California, United States

Kaiser Permanente Medical Center - Roseville, Roseville, California, United States

Sutter Cancer Center at Roseville Medical Center, Roseville, California, United States

Sutter Cancer Center, Sacramento, California, United States

South Sacramento Cancer Center, Sacramento, California, United States

South Sacramento Kaiser-Permanente Medical Center, Sacramento, California, United States

Kaiser Permanente Medical Center - Sacramento, Sacramento, California, United States

Kaiser Permanente Medical Office -Vandever Medical Office, San Diego, California, United States

Kaiser Permanente Medical Center - San Francisco Geary Campus, San Francisco, California, United States

California Pacific Medical Center - California Campus, San Francisco, California, United States

Kaiser Permanente Medical Center - Santa Teresa, San Jose, California, United States

Doctors Medical Center - San Pablo Campus, San Pablo, California, United States

Kaiser Foundation Hospital - San Rafael, San Rafael, California, United States

Sutter Health - Western Division Cancer Research Group, San Rafael, California, United States

Kaiser Permanente Medical Center - Santa Clara Kiely Campus, Santa Clara, California, United States

, Santa Clara, California, United States

Kaiser Permanente Medical Center - Santa Rosa, Santa Rosa, California, United States

Kaiser Permanente Medical Center - South San Francisco, South San Francisco, California, United States

Kaiser Permanente Medical Facility - Stockton, Stockton, California, United States

Kaiser Permanente Medical Center - Vacaville, Vacaville, California, United States

Kaiser Permanente Medical Center - Vallejo, Vallejo, California, United States

Sutter Solano Medical Center, Vallejo, California, United States

Kaiser Permanente Medical Center - Walnut Creek, Walnut Creek, California, United States

John Muir/Mt. Diablo Comprehensive Cancer Center, Walnut Creek, California, United States

Aurora Presbyterian Hospital, Aurora, Colorado, United States

Boulder Community Hospital, Boulder, Colorado, United States

Penrose Cancer Center at Penrose Hospital, Colorado Springs, Colorado, United States

St. Anthony Central Hospital, Denver, Colorado, United States

Kaiser Permanente - Denver, Denver, Colorado, United States

Porter Adventist Hospital, Denver, Colorado, United States

Presbyterian - St. Luke's Medical Center, Denver, Colorado, United States

St. Joseph Hospital, Denver, Colorado, United States

Rose Medical Center, Denver, Colorado, United States

CCOP - Colorado Cancer Research Program, Denver, Colorado, United States

Swedish Medical Center, Englewood, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

Front Range Cancer Specialists, Fort Collins, Colorado, United States

St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center, Grand Junction, Colorado, United States

North Colorado Medical Center, Greeley, Colorado, United States

Kaiser Permanente - Lafayette, Lafayette, Colorado, United States

Sky Ridge Medical Center, Lone Tree, Colorado, United States

Hope Cancer Care Center at Longmont United Hospital, Longmont, Colorado, United States

McKee Medical Center, Loveland, Colorado, United States

St. Mary - Corwin Regional Medical Center, Pueblo, Colorado, United States

North Suburban Medical Center, Thornton, Colorado, United States

Exempla Lutheran Medical Center, Wheat Ridge, Colorado, United States

Bendheim Cancer Center at Greenwich Hospital, Greenwich, Connecticut, United States

Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center, Hartford, Connecticut, United States

Tunnell Cancer Center at Beebe Medical Center, Lewes, Delaware, United States

CCOP - Christiana Care Health Services, Newark, Delaware, United States

Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, District of Columbia, United States

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital, Fort Lauderdale, Florida, United States

Memorial Cancer Institute at Memorial Regional Hospital, Hollywood, Florida, United States

Ella Milbank Foshay Cancer Center at Jupiter Medical Center, Jupiter, Florida, United States

Lakeland Regional Cancer Center at Lakeland Regional Medical Center, Lakeland, Florida, United States

CCOP - Mount Sinai Medical Center, Miami Beach, Florida, United States

Florida Hospital Cancer Institute at Florida Hospital Orlando, Orlando, Florida, United States

Cleveland Clinic Florida - Weston, Weston, Florida, United States

Piedmont Hospital, Atlanta, Georgia, United States

Northside Hospital Cancer Center, Atlanta, Georgia, United States

Saint Joseph's Hospital of Atlanta, Atlanta, Georgia, United States

CCOP - Atlanta Regional, Atlanta, Georgia, United States

WellStar Cobb Hospital, Austell, Georgia, United States

John B. Amos Cancer Center, Columbus, Georgia, United States

Charles B. Eberhart Cancer Center at DeKalb Medical Center, Decatur, Georgia, United States

Northeast Georgia Medical Center, Gainesville, Georgia, United States

Gwinnett Medical Center, Lawrenceville, Georgia, United States

Kennestone Cancer Center at Wellstar Kennestone Hospital, Marietta, Georgia, United States

Southern Regional Medical Center, Riverdale, Georgia, United States

Harbin Clinic Cancer Center - Medical Oncology, Rome, Georgia, United States

Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler, Savannah, Georgia, United States

Kaiser Permanente - Moanalua Medical Center and Clinic, Honolulu, Hawaii, United States

Saint Anthony's Hospital at Saint Anthony's Health Center, Alton, Illinois, United States

Rush-Copley Cancer Care Center, Aurora, Illinois, United States

Illinois CancerCare - Bloomington, Bloomington, Illinois, United States

St. Joseph Medical Center, Bloomington, Illinois, United States

Graham Hospital, Canton, Illinois, United States

Illinois CancerCare - Canton, Canton, Illinois, United States

Illinois CancerCare - Carthage, Carthage, Illinois, United States

Memorial Hospital, Carthage, Illinois, United States

John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, United States

Resurrection Medical Center, Chicago, Illinois, United States

University of Chicago Cancer Research Center, Chicago, Illinois, United States

Decatur Memorial Hospital Cancer Care Institute, Decatur, Illinois, United States

Elmhurst Memorial Hospital, Elmhurst, Illinois, United States

Eureka Community Hospital, Eureka, Illinois, United States

Illinois CancerCare - Eureka, Eureka, Illinois, United States

Galesburg Clinic, PC, Galesburg, Illinois, United States

Illinois CancerCare - Galesburg, Galesburg, Illinois, United States

Illinois CancerCare - Havana, Havana, Illinois, United States

Mason District Hospital, Havana, Illinois, United States

Joliet Oncology-Hematology Associates, Limited - West, Joliet, Illinois, United States

Illinois CancerCare - Kewanee Clinic, Kewanee, Illinois, United States

La Grange Memorial Hospital, La Grange, Illinois, United States

Illinois CancerCare - Macomb, Macomb, Illinois, United States

McDonough District Hospital, Macomb, Illinois, United States

Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood, Illinois, United States

Trinity Cancer Center at Trinity Medical Center - 7th Street Campus, Moline, Illinois, United States

, Moline, Illinois, United States

Illinois CancerCare - Monmouth, Monmouth, Illinois, United States

OSF Holy Family Medical Center, Monmouth, Illinois, United States

Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States

BroMenn Regional Medical Center, Normal, Illinois, United States

Community Cancer Center, Normal, Illinois, United States

Illinois CancerCare - Community Cancer Center, Normal, Illinois, United States

Community Hospital of Ottawa, Ottawa, Illinois, United States

Oncology Hematology Associates of Central Illinois, PC - Ottawa, Ottawa, Illinois, United States

Cancer Treatment Center at Pekin Hospital, Pekin, Illinois, United States

Illinois CancerCare - Pekin, Pekin, Illinois, United States

Proctor Hospital, Peoria, Illinois, United States

CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States

Oncology Hematology Associates of Central Illinois, PC - Peoria, Peoria, Illinois, United States

Methodist Medical Center of Illinois, Peoria, Illinois, United States

OSF St. Francis Medical Center, Peoria, Illinois, United States

Illinois CancerCare - Peru, Peru, Illinois, United States

Illinois Valley Community Hospital, Peru, Illinois, United States

Illinois CancerCare - Princeton, Princeton, Illinois, United States

Perry Memorial Hospital, Princeton, Illinois, United States

Swedish-American Regional Cancer Center, Rockford, Illinois, United States

Illinois CancerCare - Spring Valley, Spring Valley, Illinois, United States

Regional Cancer Center at Memorial Medical Center, Springfield, Illinois, United States

CCOP - Carle Cancer Center, Urbana, Illinois, United States

Central Dupage Cancer Center, Warrenville, Illinois, United States

St. Francis Hospital and Health Centers - Beech Grove Campus, Beech Grove, Indiana, United States

Elkhart Clinic, LLC, Elkhart, Indiana, United States

Michiana Hematology-Oncology, PC - Elkhart, Elkhart, Indiana, United States

Elkhart General Hospital, Elkhart, Indiana, United States

Howard Community Hospital, Kokomo, Indiana, United States

Center for Cancer Therapy at LaPorte Hospital and Health Services, La Porte, Indiana, United States

Saint Anthony Memorial Health Centers, Michigan City, Indiana, United States

Michiana Hematology-Oncology, PC - South Bend, Mishawaka, Indiana, United States

Saint Joseph Regional Medical Center, Mishawaka, Indiana, United States

Michiana Hematology Oncology PC - Plymouth, Plymouth, Indiana, United States

Reid Hospital & Health Care Services, Richmond, Indiana, United States

CCOP - Northern Indiana CR Consortium, South Bend, Indiana, United States

Memorial Hospital of South Bend, South Bend, Indiana, United States

South Bend Clinic, South Bend, Indiana, United States

Michiana Hematology Oncology PC - La Porte, Westville, Indiana, United States

McFarland Clinic, PC, Ames, Iowa, United States

, Bettendorf, Iowa, United States

Iowa Blood and Cancer Care, Cedar Rapids, Iowa, United States

St. Luke's Hospital, Cedar Rapids, Iowa, United States

Cedar Rapids Oncology Associates, Cedar Rapids, Iowa, United States

Mercy Regional Cancer Center at Mercy Medical Center, Cedar Rapids, Iowa, United States

Medical Oncology and Hematology Associates - West Des Moines, Clive, Iowa, United States

CCOP - Iowa Oncology Research Association, Des Moines, Iowa, United States

John Stoddard Cancer Center at Iowa Methodist Medical Center, Des Moines, Iowa, United States

Medical Oncology and Hematology Associates at John Stoddard Cancer Center, Des Moines, Iowa, United States

Medical Oncology and Hematology Associates at Mercy Cancer Center, Des Moines, Iowa, United States

Mercy Cancer Center at Mercy Medical Center - Des Moines, Des Moines, Iowa, United States

John Stoddard Cancer Center at Iowa Lutheran Hospital, Des Moines, Iowa, United States

McCreery Cancer Center at Ottumwa Regional, Ottumwa, Iowa, United States

Siouxland Hematology-Oncology Associates, LLP, Sioux City, Iowa, United States

Mercy Medical Center - Sioux City, Sioux City, Iowa, United States

St. Luke's Regional Medical Center, Sioux City, Iowa, United States

Cancer Center of Kansas, PA - Chanute, Chanute, Kansas, United States

Cancer Center of Kansas, PA - Dodge City, Dodge City, Kansas, United States

Cancer Center of Kansas, PA - El Dorado, El Dorado, Kansas, United States

Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, United States

Cancer Center of Kansas-Independence, Independence, Kansas, United States

Cancer Center of Kansas, PA - Kingman, Kingman, Kansas, United States

Lawrence Memorial Hospital, Lawrence, Kansas, United States

Cancer Center of Kansas, PA - Liberal, Liberal, Kansas, United States

Cancer Center of Kansas, PA - Newton, Newton, Kansas, United States

Cancer Center of Kansas, PA - Parsons, Parsons, Kansas, United States

Cancer Center of Kansas, PA - Pratt, Pratt, Kansas, United States

Cancer Center of Kansas, PA - Salina, Salina, Kansas, United States

Cotton-O'Neil Cancer Center, Topeka, Kansas, United States

Cancer Center of Kansas, PA - Wellington, Wellington, Kansas, United States

Associates in Womens Health, PA - North Review, Wichita, Kansas, United States

Cancer Center of Kansas, PA - Medical Arts Tower, Wichita, Kansas, United States

Cancer Center of Kansas, PA - Wichita, Wichita, Kansas, United States

CCOP - Wichita, Wichita, Kansas, United States

Via Christi Cancer Center at Via Christi Regional Medical Center, Wichita, Kansas, United States

Cancer Center of Kansas, PA - Winfield, Winfield, Kansas, United States

Cancer Resource Center at King's Daughters Medical Center, Ashland, Kentucky, United States

Central Baptist Hospital, Lexington, Kentucky, United States

Harold Alfond Center for Cancer Care, Augusta, Maine, United States

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, United States

Shore Regional Cancer Center at Memorial Hospital - Easton, Easton, Maryland, United States

Union Hospital Cancer Program at Union Hospital, Elkton MD, Maryland, United States

Sturdy Memorial Hospital, Attleboro, Massachusetts, United States

Hickman Cancer Center at Bixby Medical Center, Adrian, Michigan, United States

Saint Joseph Mercy Cancer Center, Ann Arbor, Michigan, United States

CCOP - Michigan Cancer Research Consortium, Ann Arbor, Michigan, United States

Oakwood Cancer Center at Oakwood Hospital and Medical Center, Dearborn, Michigan, United States

Green Bay Oncology, Limited - Escanaba, Escanaba, Michigan, United States

Genesys Hurley Cancer Institute, Flint, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

Great Lakes Cancer Institute at McLaren Regional Medical Center, Flint, Michigan, United States

Van Elslander Cancer Center at St. John Hospital and Medical Center, Grosse Pointe Woods, Michigan, United States

Dickinson County Healthcare System, Iron Mountain, Michigan, United States

Foote Memorial Hospital, Jackson, Michigan, United States

Borgess Medical Center, Kalamazoo, Michigan, United States

West Michigan Cancer Center, Kalamazoo, Michigan, United States

Bronson Methodist Hospital, Kalamazoo, Michigan, United States

Haematology-Oncology Associates of Ohio and Michigan, PC, Lambertville, Michigan, United States

Breslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan, United States

Sparrow Regional Cancer Center, Lansing, Michigan, United States

St. Mary Mercy Hospital, Livonia, Michigan, United States

Community Cancer Center of Monroe, Monroe, Michigan, United States

Mercy Memorial Hospital - Monroe, Monroe, Michigan, United States

Michiana Hematology Oncology PC - Niles, Niles, Michigan, United States

St. Joseph Mercy Oakland, Pontiac, Michigan, United States

Mercy Regional Cancer Center at Mercy Hospital, Port Huron, Michigan, United States

William Beaumont Hospital - Royal Oak Campus, Royal Oak, Michigan, United States

Seton Cancer Institute at Saint Mary's - Saginaw, Saginaw, Michigan, United States

Lakeside Cancer Specialists, PLLC, Saint Joseph, Michigan, United States

Lakeland Regional Cancer Care Center - St. Joseph, St. Joseph, Michigan, United States

St. John Macomb Hospital, Warren, Michigan, United States

MeritCare Bemidji, Bemidji, Minnesota, United States

Fairview Ridges Hospital, Burnsville, Minnesota, United States

Mercy and Unity Cancer Center at Mercy Hospital, Coon Rapids, Minnesota, United States

Duluth Clinic Cancer Center - Duluth, Duluth, Minnesota, United States

CCOP - Duluth, Duluth, Minnesota, United States

Miller - Dwan Medical Center, Duluth, Minnesota, United States

St. Luke's Hospital Cancer Care Center, Duluth, Minnesota, United States

Fairview Southdale Hospital, Edina, Minnesota, United States

Fergus Falls Medical Group, PA, Fergus Falls, Minnesota, United States

Mercy and Unity Cancer Center at Unity Hospital, Fridley, Minnesota, United States

Hutchinson Area Health Care, Hutchinson, Minnesota, United States

HealthEast Cancer Care at St. John's Hospital, Maplewood, Minnesota, United States

Minnesota Oncology Hematology, PA - Maplewood, Maplewood, Minnesota, United States

Virginia Piper Cancer Institute at Abbott - Northwestern Hospital, Minneapolis, Minnesota, United States

Hennepin County Medical Center - Minneapolis, Minneapolis, Minnesota, United States

Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center, Robbinsdale, Minnesota, United States

CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States

Park Nicollet Cancer Center, Saint Louis Park, Minnesota, United States

United Hospital, Saint Paul, Minnesota, United States

St. Francis Cancer Center at St. Francis Medical Center, Shakopee, Minnesota, United States

Regions Hospital Cancer Care Center, St. Paul, Minnesota, United States

Ridgeview Medical Center, Waconia, Minnesota, United States

Willmar Cancer Center at Rice Memorial Hospital, Willmar, Minnesota, United States

Minnesota Oncology Hematology, PA - Woodbury, Woodbury, Minnesota, United States

Saint Francis Medical Center, Cape Girardeau, Missouri, United States

Saint Luke's Hospital, Chesterfield, Missouri, United States

Ellis Fischel Cancer Center at University of Missouri - Columbia, Columbia, Missouri, United States

Midwest Hematology Oncology Group, Incorporated, Saint Louis, Missouri, United States

St. Anthony's Cancer Center, Saint Louis, Missouri, United States

Missouri Baptist Cancer Center, Saint Louis, Missouri, United States

Arch Medical Services, Incorporated at Center for Cancer Care and Research, Saint Louis, Missouri, United States

CCOP - St. Louis-Cape Girardeau, Saint Louis, Missouri, United States

Comprehensive Cancer Care, PC, Saint Louis, Missouri, United States

David C. Pratt Cancer Center at St. John's Mercy, Saint Louis, Missouri, United States

CCOP - Cancer Research for the Ozarks, Springfield, Missouri, United States

St. John's Regional Health Center, Springfield, Missouri, United States

Hulston Cancer Center at Cox Medical Center South, Springfield, Missouri, United States

CCOP - Montana Cancer Consortium, Billings, Montana, United States

Northern Rockies Radiation Oncology Center, Billings, Montana, United States

St. Vincent Healthcare Cancer Care Services, Billings, Montana, United States

Hematology-Oncology Centers of the Northern Rockies - Billings, Billings, Montana, United States

Billings Clinic - Downtown, Billings, Montana, United States

Bozeman Deaconess Cancer Center, Bozeman, Montana, United States

St. James Healthcare Cancer Care, Butte, Montana, United States

Big Sky Oncology, Great Falls, Montana, United States

Great Falls Clinic - Main Facility, Great Falls, Montana, United States

Sletten Cancer Institute at Benefis Healthcare, Great Falls, Montana, United States

Northern Montana Hospital, Havre, Montana, United States

St. Peter's Hospital, Helena, Montana, United States

Glacier Oncology, PLLC, Kalispell, Montana, United States

Kalispell Medical Oncology at KRMC, Kalispell, Montana, United States

Kalispell Regional Medical Center, Kalispell, Montana, United States

Montana Cancer Specialists at Montana Cancer Center, Missoula, Montana, United States

Montana Cancer Center at St. Patrick Hospital and Health Sciences Center, Missoula, Montana, United States

Cancer Resource Center - Lincoln, Lincoln, Nebraska, United States

CCOP - Missouri Valley Cancer Consortium, Omaha, Nebraska, United States

Immanuel Medical Center, Omaha, Nebraska, United States

Alegant Health Cancer Center at Bergan Mercy Medical Center, Omaha, Nebraska, United States

Creighton University Medical Center, Omaha, Nebraska, United States

University Medical Center of Southern Nevada, Las Vegas, Nevada, United States

CCOP - Nevada Cancer Research Foundation, Las Vegas, Nevada, United States

New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care, Concord, New Hampshire, United States

Center for Cancer Care at Exeter Hospital, Exeter, New Hampshire, United States

New Hampshire Oncology - Hematology, PA - Hooksett, Hooksett, New Hampshire, United States

Lakes Region General Hospital, Laconia, New Hampshire, United States

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States

Norris Cotton Cancer Center at Catholic Medical Center, Manchester, New Hampshire, United States

Hunterdon Regional Cancer Center at Hunterdon Medical Center, Flemington, New Jersey, United States

Saint Peter's University Hospital, New Brunswick, New Jersey, United States

Somerset Medical Center, Somerville, New Jersey, United States

Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare, Vineland, New Jersey, United States

Cancer Institute of New Jersey at Cooper - Voorhees, Voorhees, New Jersey, United States

New York Oncology Hematology, PC at Albany Regional Cancer Care, Albany, New York, United States

New York Oncology Hematology, PC at Albany Medical Center, Albany, New York, United States

Amsterdam Community Cancer Program, Amsterdam, New York, United States

Veterans Affairs Medical Center - Brooklyn, Brooklyn, New York, United States

CCOP - Hematology-Oncology Associates of Central New York, East Syracuse, New York, United States

Charles R. Wood Cancer Center at Glens Falls Hospital, Glens Falls, New York, United States

New York Oncology Hematology, PC - Hudson, Hudson, New York, United States

Queens Cancer Center of Queens Hospital, Jamaica, New York, United States

New York Oncology Hematology, PC - Latham, Latham, New York, United States

New York Weill Cornell Cancer Center at Cornell University, New York, New York, United States

Mount Sinai Medical Center, New York, New York, United States

Riverview Cancer Care Medical Associates, PC, Rexford, New York, United States

Nalitt Cancer Institute at Staten Island University Hospital, Staten Island, New York, United States

Veterans Affairs Medical Center - Syracuse, Syracuse, New York, United States

Samaritan Hospital at Northeast Health, Troy, New York, United States

Dickstein Cancer Treatment Center at White Plains Hospital Center, White Plains, New York, United States

Waverly Hematology Oncology, Cary, North Carolina, United States

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill, North Carolina, United States

Batte Cancer Center at Northeast Medical Center, Concord, North Carolina, United States

CaroMont Cancer Center at Gaston Memorial Hospital, Gastonia, North Carolina, United States

Wayne Memorial Hospital, Incorporated, Goldsboro, North Carolina, United States

Pardee Memorial Hospital, Hendersonville, North Carolina, United States

High Point Regional Hospital, High Point, North Carolina, United States

Emerywood Hematology/Oncology, High Point, North Carolina, United States

Kinston Medical Specialists, Kinston, North Carolina, United States

Iredell Memorial Hospital, Statesville, North Carolina, United States

Wake Forest University Comprehensive Cancer Center, Winston-Salem, North Carolina, United States

Bismarck Cancer Center, Bismarck, North Dakota, United States

Medcenter One Hospital Cancer Care Center, Bismarck, North Dakota, United States

Mid Dakota Clinic, PC, Bismarck, North Dakota, United States

St. Alexius Medical Center Cancer Center, Bismarck, North Dakota, United States

CCOP - MeritCare Hospital, Fargo, North Dakota, United States

MeritCare Broadway, Fargo, North Dakota, United States

Trinity CancerCare Center, Minot, North Dakota, United States

McDowell Cancer Center at Akron General Medical Center, Akron, Ohio, United States

Summa Center for Cancer Care at Akron City Hospital, Akron, Ohio, United States

Barberton Citizens Hospital, Barberton, Ohio, United States

Mary Rutan Hospital, Bellefontaine, Ohio, United States

Wood County Oncology Center, Bowling Green, Ohio, United States

Aultman Cancer Center at Aultman Hospital, Canton, Ohio, United States

Adena Regional Medical Center, Chillicothe, Ohio, United States

MetroHealth Cancer Care Center at MetroHealth Medical Center, Cleveland, Ohio, United States

North Coast Cancer Care - Clyde, Clyde, Ohio, United States

Riverside Methodist Hospital Cancer Care, Columbus, Ohio, United States

CCOP - Columbus, Columbus, Ohio, United States

Grant Medical Center Cancer Care, Columbus, Ohio, United States

Mount Carmel Health - West Hospital, Columbus, Ohio, United States

Doctors Hospital at Ohio Health, Columbus, Ohio, United States

Grandview Hospital, Dayton, Ohio, United States

Good Samaritan Hospital, Dayton, Ohio, United States

David L. Rike Cancer Center at Miami Valley Hospital, Dayton, Ohio, United States

Samaritan North Cancer Care Center, Dayton, Ohio, United States

CCOP - Dayton, Dayton, Ohio, United States

Grady Memorial Hospital, Delaware, Ohio, United States

Community Cancer Center, Elyria, Ohio, United States

Hematology Oncology Center, Elyria, Ohio, United States

Blanchard Valley Medical Associates, Findlay, Ohio, United States

Middletown Regional Hospital, Franklin, Ohio, United States

Wayne Hospital, Greenville, Ohio, United States

Charles F. Kettering Memorial Hospital, Kettering, Ohio, United States

Fairfield Medical Center, Lancaster, Ohio, United States

St. Rita's Medical Center, Lima, Ohio, United States

Lima Memorial Hospital, Lima, Ohio, United States

Strecker Cancer Center at Marietta Memorial Hospital, Marietta, Ohio, United States

Northwest Ohio Oncology Center, Maumee, Ohio, United States

St. Luke's Hospital, Maumee, Ohio, United States

Knox Community Hospital, Mount Vernon, Ohio, United States

Licking Memorial Cancer Care Program at Licking Memorial Hospital, Newark, Ohio, United States

Fisher-Titus Medical Center, Norwalk, Ohio, United States

St. Charles Mercy Hospital, Oregon, Ohio, United States

Toledo Clinic - Oregon, Oregon, Ohio, United States

North Coast Cancer Care, Incorporated, Sandusky, Ohio, United States

Community Hospital of Springfield and Clark County, Springfield, Ohio, United States

Flower Hospital Cancer Center, Sylvania, Ohio, United States

Mercy Hospital of Tiffin, Tiffin, Ohio, United States

Toledo Hospital, Toledo, Ohio, United States

St. Vincent Mercy Medical Center, Toledo, Ohio, United States

Medical University of Ohio Cancer Center, Toledo, Ohio, United States

CCOP - Toledo Community Hospital, Toledo, Ohio, United States

St. Anne Mercy Hospital, Toledo, Ohio, United States

Toledo Clinic, Incorporated - Main Clinic, Toledo, Ohio, United States

UVMC Cancer Care Center at Upper Valley Medical Center, Troy, Ohio, United States

Fulton County Health Center, Wauseon, Ohio, United States

Mount Carmel St. Ann's Cancer Center, Westerville, Ohio, United States

United States Air Force Medical Center - Wright-Patterson, Wright-Patterson Afb, Ohio, United States

Ruth G. McMillan Cancer Center at Greene Memorial Hospital, Xenia, Ohio, United States

Genesis - Good Samaritan Hospital, Zanesville, Ohio, United States

Bay Area Hospital, Coos Bay, Oregon, United States

Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest, Allentown, Pennsylvania, United States

Bryn Mawr Hospital, Bryn Mawr, Pennsylvania, United States

Geisinger Cancer Institute at Geisinger Health, Danville, Pennsylvania, United States

Doylestown Hospital Cancer Center, Doylestown, Pennsylvania, United States

Delaware County Regional Cancer Center at Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States

Geisinger Hazleton Cancer Center, Hazleton, Pennsylvania, United States

Cancer Center of Paoli Memorial Hospital, Paoli, Pennsylvania, United States

Cancer Center at Phoenixville Hospital, Phoenixville, Pennsylvania, United States

Pottstown Memorial Regional Cancer Center, Pottstown, Pennsylvania, United States

Geisinger Medical Group - Scenery Park, State College, Pennsylvania, United States

Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center, Wilkes-Barre, Pennsylvania, United States

CCOP - Main Line Health, Wynnewood, Pennsylvania, United States

Lankenau Cancer Center at Lankenau Hospital, Wynnewood, Pennsylvania, United States

Roper St. Francis Cancer Center at Roper Hospital, Charleston, South Carolina, United States

McLeod Regional Medical Center, Florence, South Carolina, United States

Bon Secours St. Francis Health System, Greenville, South Carolina, United States

Cancer Centers of the Carolinas - Faris Road, Greenville, South Carolina, United States

Cancer Centers of the Carolinas - Grove Commons, Greenville, South Carolina, United States

Greenville Hospital Cancer Center, Greenville, South Carolina, United States

CCOP - Greenville, Greenville, South Carolina, United States

Self Regional Cancer Center at Self Regional Medical Center, Greenwood, South Carolina, United States

Cancer Centers of the Carolinas - Greer Medical Oncology, Greer, South Carolina, United States

Cancer Centers of the Carolinas - Seneca, Seneca, South Carolina, United States

Cancer Centers of the Carolinas - Spartanburg, Spartanburg, South Carolina, United States

Rapid City Regional Hospital, Rapid City, South Dakota, United States

Brooke Army Medical Center, Fort Sam Houston, Texas, United States

Martha Jefferson Hospital Cancer Care Center, Charlottesville, Virginia, United States

Danville Regional Medical Center, Danville, Virginia, United States

Fredericksburg Oncology, Incorporated, Fredericksburg, Virginia, United States

Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County, Martinsville, Virginia, United States

Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, United States

Schiffler Cancer Center at Wheeling Hospital, Wheeling, West Virginia, United States

Aurora Memorial Hospital of Burlington, Burlington, Wisconsin, United States

Marshfield Clinic - Chippewa Center, Chippewa Falls, Wisconsin, United States

Marshfield Clinic Cancer Care at Regional Cancer Center, Eau Claire, Wisconsin, United States

Vince Lombardi Cancer Center at Aurora Lakeland Medical Center - Elkhorn, Elkhorn, Wisconsin, United States

Oncology Alliance - Franklin, Franklin, Wisconsin, United States

Oncology Alliance, SC - Milwaukee - East, Glendale, Wisconsin, United States

Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center, Green Bay, Wisconsin, United States

Green Bay Oncology, Limited at St. Mary's Hospital, Green Bay, Wisconsin, United States

St. Mary's Hospital Medical Center - Green Bay, Green Bay, Wisconsin, United States

St. Vincent Hospital Regional Cancer Center, Green Bay, Wisconsin, United States

Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center, Green Bay, Wisconsin, United States

Mercy Regional Cancer Center, Janesville, Wisconsin, United States

Oncology Alliance - Kenosha South, Kenosha, Wisconsin, United States

Gundersen Lutheran Center for Cancer and Blood, La Crosse, Wisconsin, United States

Dean Medical Center - Madison, Madison, Wisconsin, United States

Holy Family Memorial Medical Center Cancer Care Center, Manitowoc, Wisconsin, United States

Bay Area Cancer Care Center at Bay Area Medical Center, Marinette, Wisconsin, United States

Vince Lombardi Cancer Clinic - Marinette, Marinette, Wisconsin, United States

Marshfield Clinic - Marshfield Center, Marshfield, Wisconsin, United States

Aurora Advanced Healthcare East Mequon Clinic, Mequon, Wisconsin, United States

Aurora Sinai Medical Center, Milwaukee, Wisconsin, United States

Medical Consultants, Limited, Milwaukee, Wisconsin, United States

Oncology Alliance, SC - Milwaukee - South, Milwaukee, Wisconsin, United States

Marshfield Clinic - Lakeland Center, Minocqua, Wisconsin, United States

Regional Cancer Center at Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States

Green Bay Oncology, Limited - Oconto Falls, Oconto Falls, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin, United States

Aurora Health Center - Racine, Racine, Wisconsin, United States

Ministry Medical Group at Saint Mary's Hospital, Rhinelander, Wisconsin, United States

Marshfield Clinic - Indianhead Center, Rice Lake, Wisconsin, United States

Vince Lombardi Cancer Clinic - Sheboygan, Sheboygan, Wisconsin, United States

Marshfield Clinic at Saint Michael's Hospital, Stevens Point, Wisconsin, United States

Green Bay Oncology, Limited - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States

Aurora Medical Center, Summit, Wisconsin, United States

Vince Lombardi Cancer Clinic - Two Rivers, Two Rivers, Wisconsin, United States

Aurora Health Center - Waukesha, Waukesha, Wisconsin, United States

Waukesha Memorial Hospital Regional Cancer Center, Waukesha, Wisconsin, United States

Marshfield Clinic - Wausau Center, Wausau, Wisconsin, United States

Oncology Alliance, SC - Milwaukee - West, Wauwatosa, Wisconsin, United States

Aurora Women's Pavilion of West Allis Memorial Hospital, West Allis, Wisconsin, United States

Marshfield Clinic - Weston Center, Weston, Wisconsin, United States

Marshfield Clinic - Wisconsin Rapids Center, Wisconsin Rapids, Wisconsin, United States

Rocky Mountain Oncology, Casper, Wyoming, United States

Welch Cancer Center at Sheridan Memorial Hospital, Sheridan, Wyoming, United States

Contact Details

Name: Ellen L. Smith, PhD, ARNP, AOCN

Affiliation: University of Michigan

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

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