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Brief Title: T-VEC in Non-melanoma Skin Cancer
Official Title: A Phase I, Open Label, Single Arm, Single Centre Study to Evaluate Mechanism of Action of Talimogene Laherparepvec (T-VEC) in Locally Advanced Non-melanoma Skin Cancer
Study ID: NCT03458117
Brief Summary: Evaluation of the mechanism of Action of talimogene laherparepvec (T-VEC) in patients with locally advanced non-melanoma skin cancer.
Detailed Description: This study evaluates the administration of T-VEC in non-melanoma skin cancer. The aim is to evaluate the effectiveness, safety and tolerability of T-VEC in patients with non-melanoma skin cancer through determination of local immune effects after repeated T-VEC injections.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Department of Dermatology, University Hospital Zurich, Zurich, , Switzerland
Name: Reinhard Dummer, Prof. Dr.
Affiliation: vice-director dermatology
Role: PRINCIPAL_INVESTIGATOR