Spots Global Cancer Trial Database for Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy
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Trial Identification
Brief Title: Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy
Official Title: Phase III Randomized Trial of Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Monthly Carboplatin With Weekly Paclitaxel Chemotherapy
Study ID: NCT03977194
Conditions
Study Description
Brief Summary: Non Small Cell Lung Cancer (NSCLC) remains the leading cause of death by cancer in the world. Because of the increase in lung cancer incidence with age and the increase of life expectancy, about half of the patients are patients aged 70 or older. Several clinical trials have shown the interest of adding immunotherapy to standard 1st line chemotherapy in NSCLC. Although in these studies there was not necessarily a higher age limit, in fact the proportion of included patients aged 75 or older remains low (between 7 and 10%). It is therefore necessary to conduct a trial dedicated to these patients in order to determine whether immunotherapy is as effective and tolerated as in the general population.
Detailed Description:
Eligibility
Minimum Age: 70 Years
Eligible Ages: OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Abbeville - CH, Abbeville, , France
Aix-en-Provence - CH, Aix-en-Provence, , France
Annemasse - CH, Ambilly, , France
Metz - Thionville CHR, Ars-Laquenexy, , France
Auxerre - CH, Auxerre, , France
Avignon - Institut Sainte-Catherine, Avignon, , France
Avignon - CH, Avignon, , France
Bayonne - CH, Bayonne, , France
Besançon - CHU, Besançon, , France
Bobigny - APHP - Hôpital Avicenne, Bobigny, , France
Bordeaux - CHU Hôpital Haut-Lévèque, Bordeaux, , France
Bordeaux - Polyclinique Nord, Bordeaux, , France
Boulogne - Ambroise Paré, Boulogne-Billancourt, , France
Caen - CHU Côte de Nacre, Caen, , France
Cannes - CH, Cannes, , France
Carcassone - CH, Carcassonne, , France
Centre Hospitalier de Chambéry, Chambéry, , France
Chauny - Centre Hospitalier, Chauny, , France
Cholet - CH, Cholet, , France
Clamart - Hôpital Percy, Clamart, , France
Clermont Ferrand - CHU, Clermont Ferrand, , France
Colmar - CH, Colmar, , France
Cornebarrieu - Clinique des Cèdres, Cornebarrieu, , France
Dijon - Centre Georges-François Leclerc, Dijon, , France
Grenoble - CHU, Grenoble, , France
Le Mans - CHG, Le Mans, , France
Lille - GHICL, Lille, , France
Lille - Polyclinique de la Louvière, Lille, , France
Limoges - CHU, Limoges, , France
Lorient - CHBS, Lorient, , France
Lyon - Hôpital Jean Mermoz, Lyon, , France
Marseille - AP-HM Hôpital Nord, Marseille, , France
Marseille - Hôpital Européen, Marseille, , France
Marseille - Institut Paoli Calmette, Marseille, , France
Meaux - CH, Meaux, , France
Montauban - CH, Montauban, , France
Centre Hospitalier des Pays de Morlaix, Morlaix, , France
Mulhouse - GHRMSA, Mulhouse, , France
Nancy - Institut de Cancérologie de Lorraine, Nancy, , France
Nantes - CHU Hôpital Laënnec, Nantes, , France
Nice - CRLCC, Nice, , France
Orléans - CH, Orléans, , France
Paris - Hôpital Saint Joseph, Paris, , France
Paris - APHP - Hopital Tenon, Paris, , France
Paris - APHP Bichat, Paris, , France
Paris - Curie, Paris, , France
Paris - Hôpital Cochin, Paris, , France
Pau - CHG, Pau, , France
Lyon - URCOT, Pierre-Bénite, , France
Quint-Fonsegrives - Clinique de la Croix du Sud, Quint-Fonsegrives, , France
Rodez - CH, Rodez, , France
Saint-Cloud - Centre René Huguenin, Saint-Cloud, , France
La Réunion - CHU (site Félix GUYON), Saint-Denis, , France
Centre Hospitalier Mémorial de Saint-Lô, Saint-Lô, , France
Saint- Mandé - HIA Begin, Saint-Mandé, , France
La Réunion - CHU (Site Sud), Saint-Pierre, , France
Saint-Priest - Institut de Cancérologie de la Loire, Saint-priest En Jarez, , France
Saint-Etienne - CHU, Saint-Étienne, , France
Sens - CH, Sens, , France
Strasbourg - Nouvel Hôpital Civil, Strasbourg, , France
Suresnes - Hopital Foch, Suresnes, , France
Toulon - CHI, Toulon, , France
Toulon - HIA, Toulon, , France
Toulouse - CHU, Toulouse, , France
Tours - CHU, Tours, , France
Valence - CH, Valence, , France
Valenciennes - Clinique, Valenciennes, , France
Villefranche-Sur-Saône - Hôpital Nord-Ouest, Villefranche-Sur-Saône, , France
Contact Details
Name: Elisabeth QUOIX
Affiliation: Strasbourg - NHC
Role: STUDY_CHAIR
Name: Céline MASCAUX
Affiliation: Strasbourg - NHC
Role: STUDY_CHAIR
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