Spots Global Cancer Trial Database for elderly
Every month we try and update this database with for elderly cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Trial With Azacitidine in Newly Diagnosed Acute Myelogenous Leukemia (AML) Veterans Administration (VA) Elderly Patients Not Eligible for Standard Induction Therapy | NCT00728520 | Acute Myeloid L... Elderly | Azacitidine | 60 Years - | Kansas City Veteran Affairs Medical Center | |
| Geriatric Oncology Surgical Assessment and Functional rEcovery After Surgery | NCT03299270 | Elderly Solid Malignanc... | Questionnaires | 70 Years - | AUSL Romagna Rimini | |
| SArcopenia, Mobility, PHYsical Activity and Post-operative Risk of Bladder Carcinoma in the Elderly | NCT03362801 | Sarcopenia Bladder Cancer | sarcopenia and ... | 65 Years - | University Hospital, Caen | |
| Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery | NCT03335826 | Elderly Patient... Solid Organ Can... Surgical Resect... Epidural Anesth... Long-term Outco... | Combined epidur... General anesthe... | 60 Years - 90 Years | Peking University First Hospital | |
| Mortality Score in Elderly Patients With Colon Cancer | NCT04538404 | Mortality Surgery Colon Cancer | Colon Surgery | 80 Years - | University of Bologna | |
| Predictors for Low Rates of Surgical Resection in Elderly Patients With Resectable Pancreatic Ductal Adenocarcinoma | NCT06344299 | Pancreatic Duct... | potential predi... | 75 Years - 100 Years | Fudan University | |
| Ofatumumab In Older Patients With Untreated Low Or Intermediate Risk Indolent B-Cell Lymphomas | NCT01263418 | Lymphoma, Non-H... Lymphoma, Folli... Lymphoma, B-Cel... Lymphoma, Low-G... Lymphoma, Inter... | Ofatumumab | 70 Years - | UNC Lineberger Comprehensive Cancer Center | |
| A 3 Arm Randomized Study on Health-related QoL of Elderly Patients With Advanced Soft Tissue Sarcoma | NCT04780464 | Advanced Soft-t... | Doxorubicin Doxorubicin Cyclophosphamid... Prednisolone Prednisone | 65 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| CALC-1 (Cetuximab in Advanced Lung Cancer): Study of 2 Methods of Combining Cetuximab and Gemcitabine in Patients With Advanced Non Small-cell Lung Cancer | NCT00330746 | Advanced Non-Sm... | cetuximab gemcitabine gemcitabine cetuximab | 18 Years - | National Cancer Institute, Naples | |
| EWOC-1 Trial: Carboplatin +/- Paclitaxel in Vulnerable Elderly Patients With Stage III-IV Advanced Ovarian Cancer | NCT02001272 | Ovarian Cancer | Paclitaxel + Ca... Carboplatin mon... Weekly Paclitax... | 70 Years - | Hospices Civils de Lyon | |
| Impact of Surgery on the Treatment of Supratentorial Malignant Gliomas in Subjects Aged 70 and Over | NCT02892708 | Malignant Gliom... | Surgery radiotherapy | 70 Years - | Assistance Publique - Hôpitaux de Paris | |
| PREDICTive FactOR of Overall Survival Among Geriatric Assessment Tools and Disease Related Factors in Elderly Patients With High Risk Myelodysplastic Syndromes. | NCT02689622 | Myelodysplastic... | research of dis... research of com... physical perfor... | 70 Years - | University Hospital, Toulouse | |
| Effect of Geriatric Intervention in Frail Elderly Patients Receiving Chemotherapy for Colorectal Cancer | NCT02748811 | Colorectal Neop... | Intervention gr... | 70 Years - | University of Copenhagen | |
| Safety and Anti-Disease Activity of CHR-2797 (Tosedostat) in Elderly and/or Treatment Refractory Patients With Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM) | NCT00689000 | Acute Myeloid L... Myelodysplastic... Multiple Myelom... | CHR-2797 (tosed... | 18 Years - | Chroma Therapeutics | |
| Study of Oxaliplatin, Capecitabine, and Bevacizumab to Treat Older Patients With Colorectal Cancer | NCT00120172 | Colorectal Canc... Neoplasm Metast... | oxaliplatin, ca... | 65 Years - | Geriatric Oncology Consortium | |
| Geriatric Oncology Screening of Older Patients With Solid Cancers | NCT04644874 | Solid Carcinoma Frailty Age Geriatrics Screening Cancer | Geriatric 8 modified Geriat... 30 second chair... Handgrip Streng... | 70 Years - | Odense University Hospital | |
| Exercise for Physical Health in Men With Prostate Cancer | NCT00660686 | Prostatic Neopl... Osteoporosis | Resistance Exer... Flexibility Tra... | 18 Years - 100 Years | OHSU Knight Cancer Institute | |
| Attenuated SOX as First-line Treatment in Elderly Patients With Relapsed or Metastatic Gastric Cancer | NCT00961077 | Elderly S-1 Oxaliplatin First-Line Gastric Cancer | S-1 (TS-1) and ... | 65 Years - 80 Years | Soonchunhyang University Hospital | |
| Nutritional Intervention in Geriatric Oncology | NCT00459589 | Cancer Undernutrition Aging | nutritional int... usual nutrition... | 70 Years - | University Hospital, Bordeaux | |
| MILES-3: Cisplatin in Combination With Gemcitabine for Elderly Patients With Lung Cancer | NCT01405586 | Non-small Cell ... Non-small Cell ... | Gemcitabine Gemcitabine Cisplatin | 70 Years - | National Cancer Institute, Naples | |
| Study of Voreloxin (Vosaroxin) in Older Patients With Untreated Acute Myeloid Leukemia | NCT00607997 | Leukemia Acute Disease Acute Myeloid L... Nonlymphocytic ... Myelodysplastic... | vosaroxin | 60 Years - | Sunesis Pharmaceuticals | |
| Evaluation of Programs of Coordinated Care and Disease Management | NCT00627029 | Congestive Hear... Diabetes Coronary Artery... Chronic Obstruc... Cancer Cerebrovascular... Alzheimer's Dis... Psychotic Disor... Major Depressio... | Care Coordinati... | - | Mathematica Policy Research, Inc. | |
| COVID-19-Study of Immune Responses Following Vaccination Against SARS-CoV-2 | NCT04836793 | Cancer Elderly Healthy Aging | Additional biol... | 18 Years - | Centre Hospitalier Universitaire de Besancon | |
| MILES-02: Study of Chemotherapy Treatment and Toxicity in Elderly Patients With Advanced Non Small Cell Lung Cancer | NCT00401492 | Non Small Cell ... | gemcitabine pro... cisplatin vinorelbine | 70 Years - | National Cancer Institute, Naples | |
| STI 571 (GLIVEC) in the Treatment of Adult Acute Lymphoblastic Leukemia | NCT00376467 | Acute Lymphobla... | Imatinib | 18 Years - | Gruppo Italiano Malattie EMatologiche dell'Adulto | |
| Daratumumab-bortezomib-dexamethasone (Dara-VCd) vs Bortezomib-Thalidomide-Dexamethasone (VTd), Then Maintenance With Ixazomib (IXA) or IXA-Dara | NCT03896737 | Multiple Myelom... | Daratumumab plu... Velcade Thalido... | 18 Years - 65 Years | Stichting European Myeloma Network | |
| Study of Prednisone, Vinblastine, Doxorubicin, and Gemcitabine in Elderly Patients With Advanced Stages Hodgkin's Lymphoma | NCT00147875 | Hodgkin's Disea... | Prednisone Vinblastine Doxorubicin (Ad... Gemcitabine | 60 Years - 75 Years | University of Cologne | |
| Elotuzumab in Patients With Multiple Myeloma Before and After Peripheral Stem Cell Autologous Graft | NCT03393273 | Multiple Myelom... | Elotuzumab | 66 Years - | Assistance Publique - Hôpitaux de Paris | |
| A Multi-centre Study of MBVD in Elderly and/or Cardiopathic Patients Affected by Hodgkin's Lymphoma (HL) | NCT01523847 | Hodgkin Lymphom... | MBVD (Myocet+BV... | 18 Years - | Fondazione Italiana Linfomi - ETS | |
| Existential Issues in Elderly People With Cancer | NCT01309815 | Cancer | 70 Years - | Sykehuset Innlandet HF | ||
| PROACTIVE Study Evaluation of the Impact of a Multidimensional Geriatric Intervention Program | NCT02216162 | Breast Cancer | Arm A: adapted ... No intervention | 70 Years - | Hospices Civils de Lyon | |
| Umbilical Cord Transplantation for the Elderly Population | NCT01484470 | Hematologic Mal... | StemEx | 55 Years - 73 Years | Loyola University | |
| Mortality Score in Elderly Patients With Colon Cancer | NCT04538404 | Mortality Surgery Colon Cancer | Colon Surgery | 80 Years - | University of Bologna | |
| Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma | NCT04284540 | Head and Neck S... | Adjuvant hypofr... Definitive Hypo... | 70 Years - | Icahn School of Medicine at Mount Sinai | |
| Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment | NCT00210249 | Lymphoma Digestive Syste... Ovarian Disease... Pulmonary Disea... Prostatic Disea... Bladder Disease | 70 Years - | Institut Bergonié | ||
| Randomized Trial of Docetaxel and Gemcitabine Versus Gemcitabine in Elderly Patients With NSCLC | NCT00442026 | Non-small-cell ... | Docetaxel Gemcitabine Gemcitabine | 70 Years - 85 Years | Hellenic Oncology Research Group | |
| Geriatric Core Dataset (G-CODE) for Clinical Research in Elderly Cancer Patients | NCT03976531 | Cancer | 18 Years - | Institut Bergonié | ||
| Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy | NCT05337631 | HNSCC Oral Cavity Can... Oropharynx Canc... Hypopharynx Can... Larynx Cancer | 65 Years - | University Hospital Freiburg | ||
| Study of Oxaliplatin, Capecitabine, and Bevacizumab to Treat Older Patients With Colorectal Cancer | NCT00120172 | Colorectal Canc... Neoplasm Metast... | oxaliplatin, ca... | 65 Years - | Geriatric Oncology Consortium | |
| Virtual Exercise on Elderly Breast Cancer Survivors | NCT06432426 | Breast Cancer | Virtual reality... Standard physic... | 60 Years - 80 Years | Pontificia Universidad Catolica de Chile | |
| Using Walk With Ease Walking Program With Men 65 and Older Being Treated for Prostate Cancer | NCT02139774 | Prostate Cancer | Walk with Ease | 65 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Capecitabine Plus Oxaliplatin Plus Bevacizumab as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer | NCT01024504 | Metastatic Colo... | Oxaliplatin Capecitabine Bevacizumab | 70 Years - | Hellenic Oncology Research Group | |
| Study of Gleevec and Weekly Paclitaxel in Patients Aged 70 or Older With Advanced Non-small Cell Lung Cancer | NCT01011075 | Non-small Cell ... | Imatinib mesyla... Paclitaxel | 70 Years - | New Mexico Cancer Care Alliance | |
| Temozolomide in Elderly Patients With KPS < 70 | NCT01242566 | Primary Brain T... Glioblastoma | Temozolomide | 70 Years - | Assistance Publique - Hôpitaux de Paris | |
| Effect of PEEP on Arterial Oxygen Partial Pressure in Elderly Patients With Lithotomy Position Using LMA Supreme™ | NCT03390127 | Urinary Bladder... Prostatic Neopl... | PEEP | 65 Years - 79 Years | Asan Medical Center | |
| Carboplatin Plus Gemcitabine for Elderly Patients With Stage IV NSCLC | NCT02175381 | NSCLC | Carboplatin Gemcitabine | 70 Years - | Hellenic Oncology Research Group | |
| Outcomes of Oncology Therapy in the Elderly: Trajectory of Functional Decline and Correlates of Change | NCT01006902 | Cancer | 65 Years - 90 Years | University of Vermont | ||
| Docetaxel Plus Bevacizumab for Elderly Patients With Stage IV NSCLC | NCT02179567 | NSCLC | Docetaxel Bevacizumab | 70 Years - | Hellenic Oncology Research Group | |
| A Study of Low Dose Lenalidomide and Dexamethasone in Relapsed/Refractory Myeloma in Patients at High Risk for Myelosuppression | NCT00482261 | Multiple Myelom... | Lenalidomide dexamethasone aspirin | 18 Years - | Peter MacCallum Cancer Centre, Australia | |
| The Effect of Walking on Fatigue After Chemotherapy in Patients 65 and Older | NCT02191982 | Cancer Geriatric Fatigue | Walk With Ease | 65 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation | NCT01607879 | Prostate Cancer | Standard of car... Standard of car... | 60 Years - | Medical College of Wisconsin | |
| Phase II Trial of Carboplatin, 5-FU and Cetuximab in Elderly Fit (no Frailty) Patients With Recurrent/Metastatic HNSCC | NCT01864772 | Metastatic or R... | Carbo, 5FU, Cet... | 70 Years - | Groupe Oncologie Radiotherapie Tete et Cou | |
| Study of Gleevec and Weekly Paclitaxel in Patients Aged 70 or Older With Advanced Non-small Cell Lung Cancer | NCT01011075 | Non-small Cell ... | Imatinib mesyla... Paclitaxel | 70 Years - | New Mexico Cancer Care Alliance | |
| Improving Quality of Life and Function for Older Cancer Patients Receiving Radiotherapy | NCT03071640 | Elderly Cancer Radiotherapy Si... | 65 Years - | Sykehuset Innlandet HF | ||
| Evaluation of Programs of Coordinated Care and Disease Management | NCT00627029 | Congestive Hear... Diabetes Coronary Artery... Chronic Obstruc... Cancer Cerebrovascular... Alzheimer's Dis... Psychotic Disor... Major Depressio... | Care Coordinati... | - | Mathematica Policy Research, Inc. | |
| Rituximab and Alemtuzumab in Treating Older Patients With Progressive Chronic Lymphocytic Leukemia | NCT01013961 | Chronic Lymphoc... | alemtuzumab rituximab | 65 Years - | Eastern Cooperative Oncology Group | |
| SArcopenia, Mobility, PHYsical Activity and Post-operative Risk of Bladder Carcinoma in the Elderly | NCT03362801 | Sarcopenia Bladder Cancer | sarcopenia and ... | 65 Years - | University Hospital, Caen | |
| Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium | NCT03012984 | Elderly Surgery Analgesia Dexmedetomidine Complication, P... Delirium | Dexmedetomidine... Morphine analge... | 65 Years - 90 Years | Peking University First Hospital | |
| A Prospective, Multicenter, Open-label 12 Week Neoadjuvant Phase II Trial Optimizing Taxane Therapy in Elderly Patients With Low Response | NCT02214381 | Early Primary B... | Myocet Cyclophosphamid... Paclitaxel | 70 Years - | West German Study Group | |
| Capecitabine Plus Oxaliplatin Plus Bevacizumab as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer | NCT01024504 | Metastatic Colo... | Oxaliplatin Capecitabine Bevacizumab | 70 Years - | Hellenic Oncology Research Group | |
| Elderly CAncer Patient | NCT02884375 | Hematologic Mal... Solid Cancer | Extensive GA | 70 Years - | Assistance Publique - Hôpitaux de Paris | |
| Geriatric Oncology Screening of Older Patients With Solid Cancers | NCT04644874 | Solid Carcinoma Frailty Age Geriatrics Screening Cancer | Geriatric 8 modified Geriat... 30 second chair... Handgrip Streng... | 70 Years - | Odense University Hospital | |
| Phase II Trial of Carboplatin, 5-FU and Cetuximab in Elderly Fit (no Frailty) Patients With Recurrent/Metastatic HNSCC | NCT01864772 | Metastatic or R... | Carbo, 5FU, Cet... | 70 Years - | Groupe Oncologie Radiotherapie Tete et Cou | |
| Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM | NCT04195139 | Glioblastoma Mu... | Nivolumab Temozolomide | 65 Years - | University of Sydney | |
| Bendamustine + Rituximab in Older Patients With Previously Untreated Diffuse Large B-cell Lymphoma | NCT01234467 | Diffuse Large B... Lymphoma, Diffu... Diffuse Large-C... Lymphoma | Bendamustine Rituximab | 65 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Myocet Plus Endoxan for Older Patients With Breast Cancer | NCT01120171 | Breast Cancer | Cyclophosphamid... Liposomal-encap... | 18 Years - | Hellenic Oncology Research Group | |
| A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms | NCT02842229 | Myelodysplastic... Leukemia Myeloi... Multiple Myelom... Leukemia, Lymph... | 65 Years - | Celgene | ||
| Tolerance of Targeted Therapy Used in Metastatic Melanoma in Patients Aged Over 65 and 75-year-old | NCT03155217 | Metastatic Mela... | 18 Years - 110 Years | University Hospital, Montpellier | ||
| Effect of CGA for Frail Elderly Patients Operated for Colorectal Cancer - The CRC Frailty-study | NCT04358328 | Colorectal Neop... Frailty CGA | Comprehensive g... Standard care | 70 Years - | Sahlgrenska University Hospital, Sweden | |
| A Study of Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL) | NCT05144009 | Diffuse Large B... | Loncastuximab T... Rituximab | 80 Years - | ADC Therapeutics S.A. | |
| Quality of Life in Elderly Patients After Pancreatic Cancer Surgery | NCT06079229 | Pancreatic Canc... Surgery Elderly | Phone call | 70 Years - | Hospices Civils de Lyon | |
| Prospective Clinical Study of ZPR Regimen in Elderly Treatment-naive Diffuse Large B-cell Lymphoma | NCT05940064 | Diffuse Large B... | Zanubrutinib, P... | 60 Years - | Shanghai Zhongshan Hospital | |
| Older Cancer Caregiver Needs Post Hospital Discharge | NCT02099526 | Cancer Caregive... | 18 Years - | Duke University | ||
| Exercise for Physical Health in Men With Prostate Cancer | NCT00660686 | Prostatic Neopl... Osteoporosis | Resistance Exer... Flexibility Tra... | 18 Years - 100 Years | OHSU Knight Cancer Institute | |
| A Phase IV Study to Collect Data on the Efficacy and Safety of RIBociclib in Older Women With Breastcancer | NCT03956654 | Breast Cancer | Ribociclib | 70 Years - | Universitaire Ziekenhuizen KU Leuven | |
| Laparoscopic Intersphincteric Resection in Elderly Patients | NCT04673526 | Rectal Cancer | Laparoscopic in... Laparoscopic ab... | 70 Years - | ASL Verbano Cusio Ossola | |
| Immunotherapy After Radiotherapy in Elderly ESCC | NCT05791136 | Esophageal Squa... | Radiotherapy Toripalimab | 75 Years - | The Central Hospital of Lishui City | |
| Split-Dose R-CHOP for Older Adults With DLBCL | NCT03943901 | Diffuse Large B... DLBCL Cancer | Rituximab Cyclophosphamid... Doxorubicin Vincristine Prednisone Pegfilgrastim | 70 Years - | University of Wisconsin, Madison | |
| ZR2 Followed by Immunochemotherapy in Elderly Patients With Newly-diagnosed DLBCL | NCT05290090 | Diffuse Large B... | Rituximab, Lena... | 65 Years - 85 Years | Zhejiang Cancer Hospital | |
| Feasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy | NCT01789983 | Breast Cancer Colon Cancer Lung Cancer | Walk With Ease ... Collect Blood, ... | 60 Years - | UNC Lineberger Comprehensive Cancer Center |
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