Spots Global Cancer Trial Database for Measles Vaccine in Patients With Measles Virus-Positive, Advanced Non-Small Cell Lung Cancer

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Trial Identification

Brief Title: Measles Vaccine in Patients With Measles Virus-Positive, Advanced Non-Small Cell Lung Cancer

Official Title: A Single-Institution, Open-Label, Single-Arm phase1/2 Study of Measles Vaccine as Consolidation in Patients With Measles Virus-Positive, Stage 3B/4 Non-Small Cell Lung Cancer

Study ID: NCT00828022

Conditions

Non-Small Cell Lung Cancer

Measles

Interventions

attenuated measles vaccine

Study Description

Brief Summary: The objectives of the study are to assess the efficacy and safety of live, attenuated measles vaccine as consolidation therapy in patients with measles-positive, non-small cell lung cancer with locally-advanced (stage 3B with pleural effusion) or metastatic (stage 4) tumors in remission.

Detailed Description: This is a single-institution, non-randomized phase 1/2 study in patients with locally-advanced or metastatic NSCLC in remission after receiving standard systemic chemotherapy of four cycles of combination chemotherapy consisting of four cycles of cisplatin combined with vinorelbine.