Spots Global Cancer Trial Database for Feasibility of Intratumoral Washing Fluid for Detecting EGFR Mutations in Lung Cancer

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Trial Identification

Brief Title: Feasibility of Intratumoral Washing Fluid for Detecting EGFR Mutations in Lung Cancer

Official Title: Feasibility of Intratumoral Washing Fluid for Detecting EGFR Mutations in Advanced Non-small Cell Lung Cancer

Study ID: NCT05517083

Conditions

Non Small Cell Lung Cancer

EGFR Gene Mutation

Interventions

Ultarthin bronchoscopy with intratumoral washing

Study Description

Brief Summary: The purpose of this study is to evaluate the relevance of intratumoral washing for detection of EGFR mutation (including T790M positivity).

Detailed Description: This is a prospective, single-arm, open-label study to assess evaluate the relevance of intratumoral washing by ultrathin bronchoscopy (outer diameter; 3mm) for detection of EGFR mutation (including T790M positivity) using cobas real-time PCR and droplet digital PCR (DDPCR) in patients with NSCLC.