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Spots Global Cancer Trial Database for Study Comparing Bevacizumab + Erlotinib vs Erlotinib Alone as First Line Treatment of Patients With EGFR Mutated Advanced Non Squamous Non Small Cell Lung Cancer

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Trial Identification

Brief Title: Study Comparing Bevacizumab + Erlotinib vs Erlotinib Alone as First Line Treatment of Patients With EGFR Mutated Advanced Non Squamous Non Small Cell Lung Cancer

Official Title: A Randomized Open-label Phase 3 Trial Comparing Bevacizumab + Erlotinib vs Erlotinib Alone as First Line Treatment of Patients With EGFR Mutated Advanced Non Squamous Non Small Cell Lung Cancer

Study ID: NCT02633189

Study Description

Brief Summary: The purpose of this study is to test whether the combination of bevacizumab and erlotinib can prolong progression free survival as compared with erlotinib alone as first-line treatment in patients with non small cell lung cancer (NSCLC) with activating mutation of EGFR.

Detailed Description: The co-primary objectives are to assess investigator-assess, and blinded independent centrally-reviewed progression-free survival .

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Ospedale Ramazzini, Day Hospital Oncologico, Carpi, MO, Italy

Casa di Cura La Maddalena S.p.A., Dipartimento Oncologico, Palermo, PA, Italy

Ospedale di Prato, Prato, PO, Italy

Ospedale S. Chiara, Trento, TN, Italy

Ospedale S. Bortolo ULSS 6, U.O. di Oncologia Medica, Vicenza, VI, Italy

A.S.O. SS Antonio e Biagio e Cesare Arrigo, Alessandria, , Italy

A.O. S. Giuseppe Moscati, Avellino, , Italy

Centro Riferimento Oncologico, Aviano, , Italy

AO G. Rummo, Benevento, , Italy

Ospedale Senatore Antonio Perrino, Brindisi, , Italy

Ospedale A. cardarelli, Campobasso, , Italy

U.L.S.S. 15 Veneto, Camposampiero, , Italy

A.O. Garibaldi Nesima, Catania, , Italy

Centro Clinico Diagnostico G.B. Morgagni, Catania, , Italy

Policlinico vittorio Emanuele, Catania, , Italy

Ospedale Civile per gli Infermi, Faenza, , Italy

Ospedale S. Croce, Fano, , Italy

A.O.U. Arcispedale Sant'Anna, Ferrara, , Italy

Ospedale Villa Scassi, Genova, , Italy

Ospedale di Guastalla, Guastalla, , Italy

A.O. Vito Fazzi, Lecce, , Italy

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, , Italy

Istituto Europeo di Oncologia, Milano, , Italy

Istituto Nazionale Tumori, Milano, , Italy

Ospedale San Paolo, Milano, , Italy

A.O. U.L.S.S. 13, Mirano, , Italy

A.O.U. Policlinico Modena, Modena, , Italy

Azienda Ospedaliera Cardarelli, Napoli, , Italy

A.O.U. Seconda Università di Napoli, Napoli, , Italy

AORN Ospedale dei Colli - Osp Monaldi, Napoli, , Italy

Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, , Italy

Istituto Sacro Cuore Don Calabria, Negrar, , Italy

A.O.U. Maggiore della Carità, Novara, , Italy

Istituto Oncologico Veneto, Padova, , Italy

Policlinico Giaccone, Palermo, , Italy

Fondazione Salvatore Maugeri, Pavia, , Italy

Osp. S. Maria della Misericordia, Perugia, , Italy

A.O. Ospedali Riuniti Marche Nord, Pesaro, , Italy

Ospedale Guglielmo da Saliceto, Piacenza, , Italy

A.O. San Carlo, Potenza, , Italy

Ospedale Santa Maria delle Croci - AUSL, Ravenna, , Italy

Ospedale Umberto I, Ravenna, , Italy

Ospedale degli Infermi Rimini - Ospedale Cervesi Cattolica, Rimini, , Italy

IRCCS Centro di Riferimento Oncologico Basilicata, Rionero in Vulture, , Italy

Istituto Regina Elena, Roma, , Italy

Ospedale Camillo Forlanini, Roma, , Italy

Ospedale S. Giovanni Calibita Fatebenefratelli, Roma, , Italy

Policlinico Universitario Campus Bio Medico, Roma, , Italy

Ospedale di Sondrio, Sondrio, , Italy

Ospedale Fabrizio Spaziani di Frosinone, Sora, , Italy

Ospedale Maggiore, Trieste, , Italy

Azienda Ospedaliero-Universitaria S.M. della Misericordia di Udine, Udine, , Italy

Ospedale S. Andrea, Vercelli, , Italy

A.O.U. Integrata, Verona, , Italy

ASL Viterbo - Ospedale Belcolle, Viterbo, , Italy

Contact Details

Name: Cesare Gridelli, M.D.

Affiliation: S.G.Moscati Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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