Spots Global Cancer Trial Database for Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT)
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT)
Official Title: Neoadjuvant Chemoimmunotherapy With Tislelizumab, Albumin-bound Paclitaxel, and Cisplatin in Locally Advanced Oral/Oropharyngeal Squamous Cell Carcinoma: A Prospective, Multicenter, Single-arm Study
Study ID: NCT06009861
Study Description
Brief Summary: Previous studies confirmed locally advanced oral/oropharyngeal squamous cell carcinoma (LA OSCC or OPSCC) patients with a pathological response had higher probability of survival in neoadjuvant settings. Several ongoing trials of neoadjuvant immunotherapy in head and neck cancer showed promising results. However, the optimal regimen remains unclear. This trial aimed to evaluate the efficacy and safety of neoadjuvant therapy with anti-programmed cell death 1 monoclonal antibody Tislelizumab and chemotherapy, followed by surgery and adjuvant radiotherapy or chemoradiotherapy plus Tislelizumab in LA OSCC or OPSCC.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Peking University School and Hospital Stomatology, Beijing, Beijing, China
Affiliated Hospital of Hebei University, Baoding, Hebei, China
Tangshan People's Hospital, Tangshan, Hebei, China
The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
Affiliated Hospital of Chifeng College, Chifeng, Inner Mongolia, China
The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, China
The Hospital of Stomatology of Jilin University, Changchun, Jilin, China
China Medical University School and Hospital Of Stomatology, Shenyang, Liaoning, China
Shandong Provincial Hospital, Jinan, Shandong, China
Shandong Provincial Hospital, Jinan, Shandong, China
The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China
First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
Shanxi Cancer hospital, Taiyuan, Shanxi, China
Tianjin First Central Hospital, Tianjin, Tianjin, China
Contact Details
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
