Spots Global Cancer Trial Database for Oncological and Functional Outcomes in Lower Limb Osteosarcoma Pediatric Patient
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Trial Identification
Brief Title: Oncological and Functional Outcomes in Lower Limb Osteosarcoma Pediatric Patient
Official Title: Department of Orthopedic Oncology, The First Affiliated Hospital of Sun Yat-sen University
Study ID: NCT06162962
Interventions
Study Description
Brief Summary: Retrospective analysis of specific characteristics of complications and long-term oncological and function outcomes in lower-limb osteosarcoma pediatric patients.
Detailed Description: Clinical and functional outcomes were compared based on age groups, surgical methods, type of prosthesis, and primary tumor location. Patients were divided into the Low-age group (≤10 years old) and the High-age group (\>10 years old). Overall Survival rate (OS), Progression-Free Survival rate (PFS), and prosthesis survival rate were assessed using Kaplan-Meier curves, and non-parametric survival analysis (log-rank test) was used for comparison. The incidence of complications, local relapse rate (LRR), metastasis rate, final limb-salvage and amputation rate, and Musculoskeletal Tumor Society (MSTS) score of different independent groups were further evaluated using χ2 test or Fisher's exact test, and t-test was employed to evaluate the measurement data.
Keywords
Eligibility
Minimum Age: 4 Years
Eligible Ages: CHILD
Sex: ALL
Healthy Volunteers: No
Locations
Changye Zou, Guangzhou, Guangdong, China
Contact Details
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