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Spots Global Cancer Trial Database for EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Cancers When First Given Cyclophosphamide

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Trial Identification

Brief Title: EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Cancers When First Given Cyclophosphamide

Official Title: A Study to Find the Highest Dose of Biological Study Drug (EMD 273066) That Can Be Given Safely to Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-Small Cell Lung Cancers When First Given a Low Dose of Cyclophosphamide

Study ID: NCT00132522

Interventions

EMD 273066

Study Description

Brief Summary: This study is looking at the safety and tolerability of the experimental biological drug EMD 273066 when given with low dose cyclophosphamide to patients with recurring EpCAM positive ovarian, prostate, colorectal or non-small cell lung cancers. EMD 273066 is an experimental biological drug that may increase the immune response to certain cancers. Patients will be enrolled in groups of 3, with each successive group receiving a higher dose if the prior group adequately tolerates the study medication.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

City of Hope, Durate, California, United States

Dartmouth Medical School, Pharmacology & Toxicology Dept. of Medicine, Lebanon, New Hampshire, United States

Fox Chase Cancer Oncology Department of Medical Oncology, Philadelphia, Pennsylvania, United States

University of Wisconsin Division of Gynecologic Oncology, Madison, Wisconsin, United States

Centre pluridisciplinaire d'Oncologie, Lausanne, Rue du Bugnon, Switzerland

Contact Details

Name: Joseph O'Connor, MD

Affiliation: University of Wisconsin, Madison

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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