Spots Global Cancer Trial Database for colorectal
Every month we try and update this database with for colorectal cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Phase I Platinum Based Chemotherapy Plus Indomethacin | NCT01719926 | Colorectal Neop... Esophageal Neop... Ovarian Neoplas... | Indomethacin | 18 Years - | UMC Utrecht | |
| A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours | NCT05605522 | Pancreatic Duct... Squamous Cell C... Colorectal Canc... Gastric Cancer Ewing Sarcoma NTSR1 Expressin... Neuroendocrine ... | [225]-FPI-2059 [111In]-FPI-205... | 18 Years - | Fusion Pharmaceuticals Inc. | |
| De-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colorectal Cancer | NCT02842580 | Colorectal Neop... | 5 FLUOROURACYL acide folinique irinotecan Oxaliplatin capécitabine bevacizumab | 18 Years - | Federation Francophone de Cancerologie Digestive | |
| A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver | NCT01098422 | Colorectal Neop... Liver Neoplasms | Yttrium-90 Radi... | 18 Years - | University of California, San Diego | |
| A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI | NCT04247256 | Metastatic Colo... | FOLFIRI Protoco... SCO-101 | 18 Years - | Scandion Oncology A/S | |
| Radiosensitization of AVASTIN® (Bevacizumab) With Stereotactic Body Radiotherapy for Colorectal Liver Metastasis | NCT01569984 | Colorectal Canc... | Stereotactic bo... | 18 Years - | Sunnybrook Health Sciences Centre | |
| TACE With Irinotecan Drug-eluting Beads and Intravenous (IV) Cetuximab in Refractory Colorectal Cancer | NCT01060423 | Colorectal Canc... | Cetuximab Irinotecan Irinotecan elut... | 18 Years - | Martin-Luther-Universität Halle-Wittenberg | |
| Colorectal Cancer Screening Intervention for Family Members of Colorectal Cancer Patients | NCT00582829 | Colorectal Cancer Screening Intervention | Generic Print I... Tailored Print ... Tailored print ... | 40 Years - | Memorial Sloan Kettering Cancer Center | |
| De-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colorectal Cancer | NCT02842580 | Colorectal Neop... | 5 FLUOROURACYL acide folinique irinotecan Oxaliplatin capécitabine bevacizumab | 18 Years - | Federation Francophone de Cancerologie Digestive | |
| Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers | NCT00001693 | Colorectal Neop... Hereditary Nonp... | Celecoxib (SC-5... | - | National Institutes of Health Clinical Center (CC) | |
| A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer | NCT01767857 | Metastatic Colo... | Xilonix Placebo | 18 Years - | Janssen Research & Development, LLC | |
| Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver | NCT02885753 | Colorectal Neop... | Oxaliplatin int... 5 FU bolus Folinic acid Oxaliplatin int... Panitumumab Bevacizumab 5 FU continuous Irinotecan | 18 Years - | Federation Francophone de Cancerologie Digestive | |
| Study of Oxaliplatin, Capecitabine, and Bevacizumab to Treat Older Patients With Colorectal Cancer | NCT00120172 | Colorectal Canc... Neoplasm Metast... | oxaliplatin, ca... | 65 Years - | Geriatric Oncology Consortium | |
| Tenovus Cancer Choirs Study: the Benefits of Singing for Those Affected by Cancer | NCT02756780 | Cancer | Tenovus Cancer ... | 18 Years - | Royal Marsden NHS Foundation Trust | |
| Validating M.D. Anderson Symptom Inventory (MDASI-GI) in GI Cancer Patients Under Chemotherapy | NCT00849979 | Gastrointestina... | Questionnaire Interview | 18 Years - | M.D. Anderson Cancer Center | |
| EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options | NCT03602885 | Metastatic Panc... Unresectable Pa... Metastatic Colo... | Usual chemother... Chemotherapy ed... | 21 Years - | Dana-Farber Cancer Institute | |
| Study of Efficacy and Safety of S 95005 (TAS-102) in Patients With Metastatic Colorectal Cancer Who Failed Standard Chemotherapies | NCT03274882 | Metastatic Colo... | S95005 | 18 Years - | Servier | |
| Mesalazine Effects in Sporadic Colorectal Adenoma Patients | NCT01894685 | Sporadic Colore... | Mesalazine Placebo | 50 Years - 75 Years | UMC Utrecht | |
| Vitamin D Supplementation Study | NCT05506696 | Colorectal Canc... Vitamin D Defic... | Fultium | 18 Years - 100 Years | University of Edinburgh | |
| Safety/Efficacy Study of Imprime PGG With Cetuximab in Patients With Recurrent/Progressive Colorectal Carcinoma | NCT00545545 | Recurrent Color... Progressive Col... | Safety and effi... Safety and effi... | 18 Years - 75 Years | HiberCell, Inc. | |
| A Clinicobiological Database in Metastatic Digestive Cancers | NCT03978078 | Digestive Syste... | Biological coll... | 18 Years - | Institut du Cancer de Montpellier - Val d'Aurelle | |
| Geriatric Assessment and Intervention in Older Patients Undergoing Surgery for Colorectal Cancer | NCT03719573 | Colon Cancer Colon Neoplasm Frail Elderly S... Colorectal Canc... | Geriatric inter... | 65 Years - | Herlev and Gentofte Hospital | |
| Development of an IDEAL Framework to Standardise Cytoreductive Surgery for Colorectal Peritoneal Metastases | NCT03733184 | Colorectal Canc... Peritoneal Meta... | Cytoreduction a... | 18 Years - 90 Years | University of Manchester | |
| Enhancing Fitness With Preoperative Exercise in Colorectal Cancer Surgery | NCT03336229 | Colorectal Canc... | Exercise interv... | 18 Years - | NHS Greater Glasgow and Clyde | |
| "Cancersensor" Metastasis Resection | NCT01693848 | Metastatic Colo... | 18 Years - | Institut National de la Santé Et de la Recherche Médicale, France | ||
| Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC | NCT04104334 | Hyperthermia Colorectal Neop... Oxaliplatin | Remifentanil in... Remifentanil in... | 18 Years - | Ciusss de L'Est de l'Île de Montréal | |
| METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin | NCT03388190 | Colorectal Canc... | Nivolumab FLOX | 18 Years - | University Hospital, Akershus | |
| The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation | NCT03181334 | Colorectal Canc... | Branch I Branch II Branch III Branch IV Branch V | 50 Years - 74 Years | University of Texas Southwestern Medical Center | |
| Simvastatin in Colorectal Surgery | NCT00994903 | Intestinal Neop... Perioperative C... | Simvastatin Placebo | 18 Years - 90 Years | University of Auckland, New Zealand | |
| Expanded Cohort for Metastatic Colorectal Cancer (MCRC) Using Bevacizumab + Everolimus | NCT00597506 | Colorectal Aden... | Bevacizumab Everolimus | 18 Years - | Duke University | |
| Enhancing Fitness With Preoperative Exercise in Colorectal Cancer Surgery | NCT03336229 | Colorectal Canc... | Exercise interv... | 18 Years - | NHS Greater Glasgow and Clyde | |
| Enhancing Fitness With Preoperative Exercise in Colorectal Cancer Surgery | NCT03336229 | Colorectal Canc... | Exercise interv... | 18 Years - | NHS Greater Glasgow and Clyde | |
| Phase II Trial of Abraxane and Capecitabine in Metastatic Colon Cancer (COL 01) | NCT00625573 | Colorectal Canc... | Abraxane | 18 Years - 90 Years | Mt. Sinai Medical Center, Miami | |
| Study of Oxaliplatin, Capecitabine, and Bevacizumab to Treat Older Patients With Colorectal Cancer | NCT00120172 | Colorectal Canc... Neoplasm Metast... | oxaliplatin, ca... | 65 Years - | Geriatric Oncology Consortium | |
| A Study of Fruquintinib in Combination With Tislelizumab in Advanced Solid Tumors | NCT04577963 | Triple Negative... Endometrial Can... Solid Tumor, Un... Colorectal Canc... | Fruquintinib Tislelizumab | 18 Years - | Hutchmed | |
| Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours | NCT02804815 | Cancer Breast Cancer Prostate Cancer Colorectal Canc... Gastro-oesophag... | Aspirin 100mg Aspirin 300mg Placebo 100mg Placebo 300mg | 16 Years - | University College, London | |
| A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer | NCT04322539 | Metastatic Colo... Metastatic Colo... | Fruquintinib Placebo | 18 Years - | Hutchmed | |
| Abraxane in CIMP-High Colorectal and Small Bowel Adenocarcinomas | NCT01730586 | Colorectal Canc... Cancer of Gastr... | Abraxane | 18 Years - | M.D. Anderson Cancer Center | |
| A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver | NCT01098422 | Colorectal Neop... Liver Neoplasms | Yttrium-90 Radi... | 18 Years - | University of California, San Diego | |
| Exercise and Metformin in Colorectal and Breast Cancer Survivors | NCT01340300 | Colorectal Canc... Breast Cancer | Exercise traini... Metformin Educational inf... | 18 Years - | Dana-Farber Cancer Institute | |
| Colorectal Cancer Prehabilitation in Changi General Hospital | NCT05169528 | Colorectal Canc... | Colorectal Canc... | 21 Years - 99 Years | Changi General Hospital | |
| Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Bevacizumab With FOLFOX or FOLFIRI. | NCT01858649 | Metastatic Colo... | Metastases rese... Bevacizumab 5 FU Oxaliplatin Irinotecan | 18 Years - | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
| Study to Evaluate the Effects of Panitumumab if Combined With Chemotherapy for 2nd Treatment of Colorectal Cancer | NCT00950820 | Colorectal Neop... | Oxaliplatin, Ca... Oxaliplatin, Ca... | 18 Years - | AIO-Studien-gGmbH | |
| Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors | NCT04902872 | Solid Tumor, Ad... Epithelial Ovar... Small Cell Lung... Breast Cancer Colorectal Canc... Pancreas Cancer Appendix Cancer Non-small Cell ... Gastric Cancer Esophagus Cance... Urothelial Carc... Sarcoma | CBX-12 | 18 Years - | Cybrexa Therapeutics | |
| Acupuncture for Enhanced Recovery After Surgery in Patients Undergoing Laparoscopic Colorectal Cancer Resection | NCT02388256 | Colorectal Canc... | acupuncture early recovery ... | 18 Years - 75 Years | Korean Medicine Hospital of Pusan National University | |
| XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib | NCT00920868 | Solid Tumor Metastatic Colo... | dasatinib bevacizumab Oxaliplatin Capecitabine | 18 Years - | Duke University | |
| CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer | NCT05210283 | Colorectal Canc... | MRD | 18 Years - | Exact Sciences Corporation | |
| EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options | NCT03602885 | Metastatic Panc... Unresectable Pa... Metastatic Colo... | Usual chemother... Chemotherapy ed... | 21 Years - | Dana-Farber Cancer Institute | |
| A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors, Colorectal, and Breast Cancer | NCT03251378 | Advanced Solid ... Metastatic Colo... Metastatic Brea... Triple Negative... HER2-negative B... Hormone Recepto... Rectal Cancer | Fruquintinib (H... | 18 Years - | Hutchmed | |
| Tenovus Cancer Choirs Study: the Benefits of Singing for Those Affected by Cancer | NCT02756780 | Cancer | Tenovus Cancer ... | 18 Years - | Royal Marsden NHS Foundation Trust | |
| Study to Evaluate the Efficacy and Safety of FOLFOX-4 Plus Cetuximab Versus UFOX Plus Cetuximab. | NCT00439517 | Previously Untr... | UFOX + Cetuxima... FOLFOX4 + Cetux... | 18 Years - | Merck KGaA, Darmstadt, Germany | |
| A Study to Assess PV-10 Chemoablation of Cancer of the Liver | NCT00986661 | Cancer Metastat... Hepatocellular ... Metastatic Mela... Metastatic Ocul... Metastatic Uvea... Metastatic Lung... Metastatic Colo... Metastatic Colo... Metastatic Brea... Metastatic Panc... | PV-10 (10% rose... | 18 Years - | Provectus Pharmaceuticals | |
| XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib | NCT00920868 | Solid Tumor Metastatic Colo... | dasatinib bevacizumab Oxaliplatin Capecitabine | 18 Years - | Duke University | |
| A Phase II Study of Bevacizumab, Irinotecan and Capecitabine in Patients With Previously Untreated Metastatic Colorectal Cancer | NCT00483834 | Colorectal Canc... | Bevacizumab Irinotecan Capecitabine | 18 Years - | University Health Network, Toronto | |
| EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Cancers When First Given Cyclophosphamide | NCT00132522 | Ovarian Cancer Colorectal Canc... Carcinoma, Non-... Prostate Cancer | EMD 273066 | 18 Years - | EMD Serono | |
| Regorafenib and Nivolumab in Mismatch Repair (MMR) Refractory Colorectal Cancer | NCT03712943 | Colorectal Canc... Metastatic Colo... Colon Cancer | Regorafenib Nivolumab | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| A Phase I Study of ECO-4601 in Patients With Advanced Cancer | NCT00338026 | Tumors Glioma Colorectal Canc... Lung Cancer Breast Cancer Ovarian Cancer Pancreatic Canc... Prostate Cancer | ECO-4601 | 18 Years - | Thallion Pharmaceuticals | |
| Colorectal Cancer Screening Intervention for Family Members of Colorectal Cancer Patients | NCT00582829 | Colorectal Cancer Screening Intervention | Generic Print I... Tailored Print ... Tailored print ... | 40 Years - | Memorial Sloan Kettering Cancer Center | |
| Preoperative Panitumumab and Radiotherapy in Rectal Cancer | NCT00973193 | Rectal Cancer | panitumumab | 18 Years - | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
| The Effect of Fish Oils on Human Hepatic Colorectal Metastases | NCT00942292 | Colorectal Live... | Lipidem- fish o... Digital Contras... | 18 Years - 80 Years | University Hospitals, Leicester | |
| Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers | NCT00001693 | Colorectal Neop... Hereditary Nonp... | Celecoxib (SC-5... | - | National Institutes of Health Clinical Center (CC) | |
| Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer | NCT03659448 | Colorectal Neop... | SGM-101 | 18 Years - | Surgimab | |
| Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours | NCT02804815 | Cancer Breast Cancer Prostate Cancer Colorectal Canc... Gastro-oesophag... | Aspirin 100mg Aspirin 300mg Placebo 100mg Placebo 300mg | 16 Years - | University College, London | |
| EPO906 Therapy in Patients With Advanced Colorectal Cancer | NCT00035087 | Colorectal Neop... Colonic Neoplas... | epothilone b | 18 Years - 85 Years | Novartis | |
| Local Consolidative Therapy in Colorectal Cancer | NCT05062720 | Colorectal Canc... | Local consolida... | 18 Years - | Fox Chase Cancer Center | |
| A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal Cancer | NCT00500292 | Colorectal Cancer | Vandetanib FOLFOX regimen=... | 18 Years - | Sanofi | |
| Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer | NCT02045030 | Metastatic Colo... | aflibercept + F... | 18 Years - | CR-CSSS Champlain-Charles-Le Moyne | |
| Adjuvant Aflibercept for Metastatic Colorectal Cancer | NCT01669720 | Metastatic Colo... | Aflibercept | 18 Years - | Brown University | |
| A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal Cancer | NCT00500292 | Colorectal Cancer | Vandetanib FOLFOX regimen=... | 18 Years - | Sanofi | |
| Tarceva, Capecitabine and Oxaliplatin for Metastatic Colorectal Cancer | NCT00123851 | Colorectal Canc... Neoplasm Metast... | Tarceva (OSI-77... Capecitabine Oxaliplatin | 18 Years - | Dana-Farber Cancer Institute | |
| Expanded Cohort for Metastatic Colorectal Cancer (MCRC) Using Bevacizumab + Everolimus | NCT00597506 | Colorectal Aden... | Bevacizumab Everolimus | 18 Years - | Duke University | |
| Microwave Ablation Versus Resection for Resectable Colorectal Liver Metastases | NCT02642185 | Neoplasm Metast... | Microwave ablat... Resection | 18 Years - 90 Years | Karolinska Institutet | |
| Development of an IDEAL Framework to Standardise Cytoreductive Surgery for Colorectal Peritoneal Metastases | NCT03733184 | Colorectal Canc... Peritoneal Meta... | Cytoreduction a... | 18 Years - 90 Years | University of Manchester | |
| CITRuS Stage 1; Feasibility | NCT04697394 | Colorectal Canc... | 18 Years - | Royal Surrey County Hospital NHS Foundation Trust | ||
| NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors | NCT04332653 | Any Advanced So... Triple Negative... Non Small Cell ... Small Cell Lung... Microsatellite ... Pancreatic Canc... Ovarian Cancer | NT-I7 pembrolizumab (... | 18 Years - | NeoImmuneTech | |
| "Cancersensor" Metastasis Resection | NCT01693848 | Metastatic Colo... | 18 Years - | Institut National de la Santé Et de la Recherche Médicale, France | ||
| Exercise Program for Colorectal Older Patients | NCT05448846 | Colorectal Neop... Aged | Enhanced Recove... Home-based mult... | 75 Years - | Hospital General Universitario Gregorio Marañon | |
| TREM-1 - a New Marker of Serious Infectious Complications in Colorectal Surgery? | NCT05933408 | Colorectal (Col... | TREM-1 | 18 Years - | Jagiellonian University | |
| A Study of Fruquintinib in Combination With Tislelizumab in Advanced Solid Tumors | NCT04577963 | Triple Negative... Endometrial Can... Solid Tumor, Un... Colorectal Canc... | Fruquintinib Tislelizumab | 18 Years - | Hutchmed | |
| Validating M.D. Anderson Symptom Inventory (MDASI-GI) in GI Cancer Patients Under Chemotherapy | NCT00849979 | Gastrointestina... | Questionnaire Interview | 18 Years - | M.D. Anderson Cancer Center |
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