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Brief Title: Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
Official Title: A Phase 1/2 Dose-Finding Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy
Study ID: NCT04068896
Brief Summary: Study of NGM120 in subjects with advanced solid tumors and and pancreatic cancer (Part 1 and 2) and metastatic castration resistant prostate cancer (Part 3).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
NGM Clinical Study Site, Tucson, Arizona, United States
NGM Clinical Study Site, Los Angeles, California, United States
NGM Clinical Study Site, Los Angeles, California, United States
NGM Clinical Study Site, Sacramento, California, United States
NGM Clinical Study Site, San Diego, California, United States
NGM Clinical Study Site, Santa Monica, California, United States
NGM Clinical Study Site, Aurora, Colorado, United States
NGM Clinical Study Site, Washington, District of Columbia, United States
NGM Clinical Study Site, Miami, Florida, United States
NGM Clinical Study Site, Chicago, Illinois, United States
NGM Clinical Study Site, Baltimore, Maryland, United States
NGM Clinical Study Site, Omaha, Nebraska, United States
NGM Clinical Study Site, Charlotte, North Carolina, United States
NGM Clinical Study Site, Cincinnati, Ohio, United States
NGM Clinical Study Site, Philadelphia, Pennsylvania, United States
NGM Clinical Study Site, Charleston, South Carolina, United States
NGM Clinical Study Site, Myrtle Beach, South Carolina, United States
NGM Clinical Study Site, Nashville, Tennessee, United States
NGM Clinical Study Site, Dallas, Texas, United States
NGM Clinical Study Site, Houston, Texas, United States
NGM Clinical Study Site, Seattle, Washington, United States
NGM Clinical Study Site, Milwaukee, Wisconsin, United States
Name: NGM Study Director
Affiliation: NGM Biopharmaceuticals, Inc
Role: STUDY_DIRECTOR