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Brief Title: A Randomized Phase III Trial Comparing Folfirinox to Gemcitabine in Locally Advanced Pancreatic Carcinoma
Official Title: A Randomized Phase III Trial Comparing Chemotherapy With Folfirinox to Gemcitabine in Locally Advanced Pancreatic Carcinoma
Study ID: NCT02539537
Brief Summary: French national multicentric phase III trial evaluating chemotherapy with Folfirinox or gemcitabine in locally advanced pancreatic carcinoma.
Detailed Description: Comparative interventional prospective phase 3, randomized, open-label, multicentric trial comparing chemotherapy with Folfirinox to Gemcitabine in locally advanced pancreatic carcinoma.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Centre Hospitalier Intercommunal Aix-Pertuis, Aix-en-Provence, , France
CHU Amiens - Hôpital Nord, Amiens, , France
CHU d'Angers, Angers, , France
Centre hospitalier d'Auxerre, Auxerre, , France
Centre hospitalier Henri Duffaut, Avignon, , France
Hôpital Avicenne, Bobigny, , France
Institut Bergonié, Bordeaux, , France
Polyclinique Bordeaux Nord, Bordeaux, , France
CH Boulogne sur Mer, Boulogne sur Mer, , France
CHU Côte de Nacre, Caen, , France
Centre François Baclesse, Caen, , France
Hôpital Trousseau, Chambray-les-tours, , France
Hôpitaux civils de Colmar, Colmar, , France
CH de Dijon, Dijon, , France
CHD Vendée, La Roche Sur Yon, , France
Centre Hospitalier de Laon, Laon, , France
Centre Oscar Lambret, Lille, , France
CHU de Limoges, Limoges, , France
Hôpital Edouard Herriot - Lyon, Lyon, , France
Hôpital Saint Joseph Saint Luc, Lyon, , France
Hôptal Européen, Marseille, , France
Hôpital De La Timone, Marseille, , France
Centre Hospitalier de Meaux, Meaux, , France
Groupe Hospitalier du Havre Jacques Monod, Montivilliers, , France
CHU Hotel Dieu, Nantes, , France
Centre Antoine Lacassagne, Nice, , France
CHR d'Orléans La Source, Orléans, , France
Hôpital Saint Antoine, Paris, , France
Groupe hospitalier Paris Saint Joseph, Paris, , France
Groupe hospitalier Pitié Salpétrière, Paris, , France
CH Annecy Genevois, Pringy, , France
CHU - Robert Debre, Reims, , France
CHU Rouen, Rouen, , France
Hôpital Privé des Côtes d'Armor, Saint Brieuc, , France
Centre Regional René Gauducheau, Saint Herblain, , France
Centre Hospitalier de Saint Malo, Saint Malo, , France
Institut de cancérologie Lucien Neuwirth, Saint Priest En Jarez, , France
CHI Elbeuf, Saint-Aubin-lès-Elbeuf, , France
Clinique mutualiste de l'Estuaire, Saint-Nazaire, , France
Hôpital privé Saint Claude, Saint-quentin, , France
Centre Hospitalier de Soissons, Soissons, , France
Centre Paul Strass, Strasbourg, , France
Polyclinique de l'Ormeau-GROP, Tarbes, , France
Centre Hospitalier de Rangueil, Toulouse, , France
Gustave Roussy, Villejuif, , France
Name: Michel DUCREUX, Professor
Affiliation: Gustave Roussy, Cancer Campus, Grand Paris
Role: PRINCIPAL_INVESTIGATOR