Spots Global Cancer Trial Database for Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?
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Trial Identification
Brief Title: Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?
Official Title: A Phase III Multicenter, Open Label Randomized Controlled Trial of Cefoxitin Versus Piperacillin-Tazobactam as Surgical Antibiotic Prophylaxis in Patients Undergoing Pancreatoduodenectomy
Study ID: NCT03269994
Study Description
Brief Summary: The purpose of this study is to figure out which commonly used antibiotic, cefoxitin or piperacillin-tazobactam, is better at decreasing the rate of surgical site infections after pancreatoduodenectomy.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
UC Davis Comprehensive Cancer Center, Sacramento, California, United States
Emory University School of Medicine, Atlanta, Georgia, United States
Northwestern Medicine (Data Collection), Chicago, Illinois, United States
NorthShore University Health System, Evanston, Illinois, United States
Indiana University, Indianapolis, Indiana, United States
University of Iowa, Iowa City, Iowa, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
University of Washington School of Medicine, Saint Louis, Missouri, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
Memorial Sloan Kettering Basking Ridge (Consent only), Basking Ridge, New Jersey, United States
Hackensack Meridian Health / Hackensack University Medical Center Cancer Center, Hackensack, New Jersey, United States
Montefiore Health Systems (Montefiore Medical Center), Bronx, New York, United States
Memorial Sloan Kettering Commack (Consent only), Commack, New York, United States
Memoral Sloan Kettering Westchester (Consent only), Harrison, New York, United States
Mount Sinai Hospital, New York, New York, United States
Mount Sinai West, New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Duke University, Durham, North Carolina, United States
Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States
Ohio State University, Columbus, Ohio, United States
Providence Health & Services (Portland Med Ctr), Portland, Oregon, United States
Pennsylvania State Hershey, Hershey, Pennsylvania, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Baptist Memorial Healthcare, Memphis, Tennessee, United States
Baylor Scott & White Health, Dallas, Texas, United States
Intermountain Healthcare, Murray, Utah, United States
University of Utah, Salt Lake City, Utah, United States
Gundersen Lutheran Medical Foundation, La Crosse, Wisconsin, United States
University of Wisconsin, Madison, Wisconsin, United States
Hamilton Health Sciences Center (Juravinski Hospital), Hamilton, Ontario, Canada
Ottawa Hospital, Ottawa, Ontario, Canada
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Contact Details
Name: Michael D'Angelica, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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