Spots Global Cancer Trial Database for HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study
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Trial Identification
Brief Title: HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study
Official Title: HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study
Study ID: NCT04694495
Interventions
Study Description
Brief Summary: The purpose of this study to access the relations between genital microecology, HPV infection and cervical intraepithelial neoplasia of childbearing-age female in China
Detailed Description: The volunteers will be recruited from the women who come to the hospital to do the thinprep cytologic test. After being informed about the potential risks, each volunteer giving written informed consent will be asked to complete a questionnaire. Then, cervical and vaginal swabs and cervical exfoliated cells will be taken from each volunteer to perform 16S rRNA gene sequencing microecology assessment on cervical secretions and detection and genotyping of HPV and pathogens of sexually transmitted diseases. If there is something abnormal with the diagnostic outcomes in the previous examinations, according to the doctor's judgement, those volunteer will be asked to undergo a vaginoscope and a cervical biopsy to evaluate the grade of cervical intraepithelial neoplasia. After six months since the entry, each volunteer will be asked to go back to each research center to do the same sampling and examination as previously did in entry.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Locations
The First Affiliated Hospital of USTC, Hefei, Anhui, China
The First Hospital of Lanzhou University, Lanzhou, Gansu, China
Chaozhou Central Hospital, Chaozhou, Guangdong, China
Dongguan People's Hospital, Dongguan, Guangdong, China
Guangdong Provincial Hospital of Intergrated Traditional Chinese and Western Medicine, Foshan, Guangdong, China
Zhujiang Hospital, Guangzhou, Guangdong, China
Nanfang Hospital, Guangzhou, Guangdong, China
Taihe Branch of Nanfang Hospital, Guangzhou, Guangdong, China
The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China
The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China
Huizhou Municipal Central Hospital, Huizhou, Guangdong, China
Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China
Shenzhen Luohu Hospital Group Luohu People's Hospital, Shenzhen, Guangdong, China
The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China
The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China
Xiaolan People's Hospital of Zhongshan, Zhongshan, Guangdong, China
The First Affiliated Hospital, Sun Yat-Sen Univeristy, Guangzhou, Guangzhou, China
Zhuhai Women and Children's Hospital, Zhuhai, Guangzhou, China
The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
The First People's Hospital of Zunyi, Zunyi, Guizhou, China
Yue Bei People's Hospital, Shaoguan, Gunagdong, China
Hainan General Hospital, Haikou, Hainan, China
The Second Hospital of Hebei Medical University, Shijia Zhuang, Hebei, China
The First Hospital fo Qiqihar, Qiqihar, Hei Longjiang, China
The Second People's Hospital of Lianyungang, Lianyungang, Jiangsu, China
Jilin Central General Hospital, Jilin, Jilin, China
General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China
Qinghai Red Cross Hospital, Xining, Qinghai, China
Jinan Central Hospital, Jinan, Shandong, China
Obstetrics&Gynecology Hospital of Fudan University, Shanghai, Shanghai, China
Changzhi People's Hospital, Changzhi, Shanxi, China
The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China
The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China
Tibet Autonomous Region People's Hospital, Lasa, Tibet, China
Yan'an Hospital of Kunming City, Kunming, Yunnan, China
Sir Run Run Shaw Hospital, Hanzhou, Zhejiang, China
Changsha Central Hospital, Changsha, , China
The Third Affiliated Hospital of CQMU, Chongqing, , China
The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, , China
Shanghai East Hospital Tongji University, Shanghai, , China
Contact Details
Name: Hongwei Zhou, Doctor
Affiliation: Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University
Role: PRINCIPAL_INVESTIGATOR
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