Spots Global Cancer Trial Database for Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors
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Trial Identification
Brief Title: Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors
Official Title: Molecular and Immunohistochemical Profiling of Tumor From Patients With Parathyroid Tumors for Evaluation of Targeted Agents
Study ID: NCT03039439
Study Description
Brief Summary: This trial studies molecular and immunohistochemical profiling of tumors in patients with parathyroid tumors. Studying molecular and immunohistochemical profiling of tumors may help doctors avoid inconsistencies in diagnosis, unnecessary or incomplete surgery, surgical morbidity, psychological stress, and inadequate follow up.
Detailed Description: PRIMARY OBJECTIVES: I. To determine the differences in clinical behavior and immunohistochemical (IHC) biomarkers between parathyroid carcinoma (PC), atypical neoplasm (AN) and parathyroid adenoma (PA). II. To determine which potential genes can be used in patients with parathyroid tumors for diagnostic purposes. OUTLINE: Previously collected tumor tissue and blood samples are analyzed via immunohistochemical profiling for identifying potential genes showing molecular aberrations as other types of cancer.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
M D Anderson Cancer Center, Houston, Texas, United States
Contact Details
Name: Nancy Perrier
Affiliation: M.D. Anderson Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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