The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Brief Title: Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome
Official Title: Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome
Study ID: NCT02943291
Brief Summary: The primary aim of this trial is to investigate adipose tissue function in women with and without polycystic ovary syndrome (PCOS). PCOS is a common endocrine disorder in young women. The pathogenesis behind PCOS is complex and only partly understood, and deeper mechanistic insight is needed. Insulin resistance is a central feature of PCOS, and recent studies have suggested that this is linked to aberrant adipose tissue function. Exercise training has been found to improve the symptoms in PCOS, but we need more knowledge about why. While processes involved in skeletal muscle oxidative remodeling are well described, it is to a large extent unknown whether the oxidative capacity of human adipose tissue is modified by endurance training. The women included in this study will be matched (for body mass index, body weight, and age) to participants in another study. This will enable the investigators to do a comparison between cases (women with PCOS) and controls (women without PCOS) at baseline, and to assess the responses to exercise training in adipose tissue.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: No
Centre of Exercise and Nutrition, Mary MacKillop Institute for Health Research, AUC, Melbourne, , Australia
Department of circulation and medical imaging , NTNU, Trondheim, , Norway
Name: Jorunn L Helbostad, phd prof
Affiliation: Norwegian University of Science and Technology
Role: STUDY_DIRECTOR