Spots Global Cancer Trial Database for Trial of Chemotherapy in Ovarian, Fallopian Tube and Peritoneal Carcinoma
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Trial Identification
Brief Title: Trial of Chemotherapy in Ovarian, Fallopian Tube and Peritoneal Carcinoma
Official Title: Neoadjuvant Platinum-based Chemotherapy in Advanced Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma Trial Protocol
Study ID: NCT01519869
Interventions
Study Description
Brief Summary: This is a prospective study to evaluate the hypothesis that platinum-based neoadjuvant chemotherapy followed by interval surgical debulking with platinum-based adjuvant chemotherapy is associated with improved maximal surgical cytoreduction rates, comparable survival, decreased morbidity, and increased quality of life in patients with International Federation of Gynecologic Oncology stages IIIC and IV ovarian, primary peritoneal, or fallopian tube cancer when compared to historical controls and to evaluate the hypothesis that cancer induced inflammation is a predictor of poor prognosis and response to therapy in this group of ovarian cancer patients.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Kentucky Markey Cancer Center, Lexington, Kentucky, United States
Contact Details
Name: Rachel Miller, MD
Affiliation: Lucille P. Markey Cancer Center at University of Kentucky
Role: PRINCIPAL_INVESTIGATOR
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